Detecting multimodal misinformation on social media remains challenging due to inconsistencies between modalities, changes in temporal patterns, and substantial class imbalance. Many existing methods treat posts independently and fail to capture the event-level structure that connects them across time and modality. We propose E-CaTCH, an interpretable and scalable framework for robustly detecting misinformation. If needed, E-CaTCH clusters posts into pseudo-events based on textual similarity and temporal proximity, then processes each event independently. Within each event, textual and visual features are extracted using pre-trained BERT and ResNet encoders, refined via intra-modal self-attention, and aligned through bidirectional cross-modal attention. A soft gating mechanism fuses these representations to form contextualized, content-aware embeddings of each post. To model temporal evolution, E-CaTCH segments events into overlapping time windows and uses a trend-aware LSTM, enhanced with semantic shift and momentum signals, to encode narrative progression over time. Classification is performed at the event level, enabling better alignment with real-world misinformation dynamics. To address class imbalance and promote stable learning, the model integrates adaptive class weighting, temporal consistency regularization, and hard-example mining. The total loss is aggregated across all events. Extensive experiments on Fakeddit, IND, and COVID-19 MISINFOGRAPH demonstrate that E-CaTCH consistently outperforms state-of-the-art baselines. Cross-dataset evaluations further demonstrate its robustness, generalizability, and practical applicability across diverse misinformation scenarios.

Quantum Reservoir Computing (QRC) uses quantum dynamics to efficiently process temporal data. In this work, we investigate a QRC framework based on two coupled Kerr nonlinear oscillators, a system well-suited for time-series prediction tasks due to its complex nonlinear interactions and potentially high-dimensional state space. We explore how its performance in time-series prediction depends on key physical parameters: input drive strength, Kerr nonlinearity, and oscillator coupling, and analyze the role of entanglement in improving the reservoir's computational performance, focusing on its effect on predicting non-trivial time series. Using logarithmic negativity to quantify entanglement and normalized root mean square error (NRMSE) to evaluate predictive accuracy, our results suggest that entanglement provides a computational advantage on average-up to a threshold in the input frequency-that persists under some levels of dissipation and dephasing. In particular, we find that higher dissipation rates can enhance performance. While the entanglement advantage manifests as improvements in both average and worst-case performance, it does not lead to improvements in the best-case error. These findings contribute to the broader understanding of quantum reservoirs for high performance, efficient quantum machine learning and time-series forecasting.

The rapid expansion in the size of new datasets has created a need for fast and efficient parameter-learning techniques. Compressive learning is a framework that enables efficient processing by using random, non-linear features to project large-scale databases onto compact, information-preserving representations whose dimensionality is independent of the number of samples and can be easily stored, transferred, and processed. These database-level summaries are then used to decode parameters of interest from the underlying data distribution without requiring access to the original samples, offering an efficient and privacy-friendly learning framework. However, both the encoding and decoding techniques are typically randomized and data-independent, failing to exploit the underlying structure of the data. In this work, we propose a framework that meta-learns both the encoding and decoding stages of compressive learning methods by using neural networks that provide faster and more accurate systems than the current state-of-the-art approaches. To demonstrate the potential of the presented Compressive Meta-Learning framework, we explore multiple applications -- including neural network-based compressive PCA, compressive ridge regression, compressive k-means, and autoencoders.

Predictive coding, the term used in the legal industry for document classification using machine learning, presents additional challenges when the dataset comprises instant messages, due to their informal nature and smaller sizes. In this paper, we exploit a data management workflow to group messages into day chats, followed by feature selection and a logistic regression classifier to provide an economically feasible predictive coding solution. We also improve the solution's baseline model performance by dimensionality reduction, with focus on quantitative features. We test our methodology on an Instant Bloomberg dataset, rich in quantitative information. In parallel, we provide an example of the cost savings of our approach.

While progress has been made in identifying common genetic variants associated with human diseases, for most of common complex diseases, the identified genetic variants only account for a small proportion of heritability. Challenges remain in finding additional unknown genetic variants predisposing to complex diseases. With the advance in next-generation sequencing technologies, sequencing studies have become commonplace in genetic research. The ongoing exome-sequencing and whole-genome-sequencing studies generate a massive amount of sequencing variants and allow researchers to comprehensively investigate their role in human diseases. The discovery of new disease-associated variants can be enhanced by utilizing powerful and computationally efficient statistical methods. In this paper, we propose a functional analysis of variance (FANOVA) method for testing an association of sequence variants in a genomic region with a qualitative trait. The FANOVA has a number of advantages: (1) it tests for a joint effect of gene variants, including both common and rare; (2) it fully utilizes linkage disequilibrium and genetic position information; and (3) allows for either protective or risk-increasing causal variants. Through simulations, we show that FANOVA outperform two popularly used methods - SKAT and a previously proposed method based on functional linear models (FLM), - especially if a sample size of a study is small and/or sequence variants have low to moderate effects. We conduct an empirical study by applying three methods (FANOVA, SKAT and FLM) to sequencing data from Dallas Heart Study. While SKAT and FLM respectively detected ANGPTL 4 and ANGPTL 3 associated with obesity, FANOVA was able to identify both genes associated with obesity.

Conformal prediction is a popular uncertainty quantification method that augments a base predictor with prediction sets with statistically valid coverage guarantees. However, current methods are often computationally expensive and data-intensive, as they require constructing an uncertainty model before calibration. Moreover, existing approaches typically represent the prediction sets with intervals, which limits their ability to capture dependencies in multi-dimensional outputs. We address these limitations by introducing zono-conformal prediction, a novel approach inspired by interval predictor models and reachset-conformant identification that constructs prediction zonotopes with assured coverage. By placing zono-topic uncertainty sets directly into the model of the base predictor, zono-conformal predictors can be identified via a single, data-efficient linear program. While we can apply zono-conformal prediction to arbitrary nonlinear base predictors, we focus on feed-forward neural networks in this work. Aside from regression tasks, we also construct optimal zono-conformal predictors in classification settings where the output of an uncertain predictor is a set of possible classes. We provide probabilistic coverage guarantees and present methods for detecting outliers in the identification data. In extensive numerical experiments, we show that zono-conformal predictors are less conservative than interval predictor models and standard conformal prediction methods, while achieving a similar coverage over the test data.

Text-to-image (T2I) models based on diffusion and transformer architectures advance rapidly. They are often pretrained on large corpora, and openly shared on a model platform, such as HuggingFace. Users can then build up AI applications, e.g., generating media contents, by adopting pretrained T2I models and fine-tuning them on the target dataset. While public pretrained T2I models facilitate the democratization of the models, users face a new challenge: which model can be best fine-tuned based on the target data domain? Model selection is well addressed in classification tasks, but little is known in (pretrained) T2I models and their performance indication on the target domain. In this paper, we propose the first model selection framework, M&C, which enables users to efficiently choose a pretrained T2I model from a model platform without exhaustively fine-tuning them all on the target dataset. The core of M&C is a matching graph, which consists of: (i) nodes of available models and profiled datasets, and (ii) edges of model-data and data-data pairs capturing the fine-tuning performance and data similarity, respectively. We then build a model that, based on the inputs of model/data feature, and, critically, the graph embedding feature, extracted from the matching graph, predicts the model achieving the best quality after fine-tuning for the target domain. We evaluate M&C on choosing across ten T2I models for 32 datasets against three baselines. Our results show that M&C successfully predicts the best model for fine-tuning in 61.3% of the cases and a closely performing model for the rest.

Posted with permission from KICS (Aug 7, 2025). The published version may differ. Abstract --Since the Fourth Industrial Revolution, AI technology has been widely used in many fields, but there are several limitations that need to be overcome, including overfitting/underfitting, class imbalance, and the limitations of representation (hypothesis space) due to the characteristics of different models. As a method to overcome these problems, ensemble, commonly known as model combining, is being extensively used in the field of machine learning. Among ensemble learning methods, voting ensembles have been studied with various weighting methods, showing performance improvements. However, the existing methods that reflect the pre-information of classifiers in weights consider only one evaluation criterion, which limits the reflection of various information that should be considered in a model realistically. Therefore, this paper proposes a method of making decisions considering various information through c ooperative games in multi -criteria situations. Using this method, various types of information known beforehand in classifiers can be simultaneously considered and reflected, leading to appropriate weight distribution and performance improvement. The machine learning algorithms were applied to the Open - ML -CC18 dataset and compared with existing ensemble weighting methods. The experimental results showed superior performance compared to other weighting methods. I NTRODUCTION ecently, artificial intelligence (AI) has been making significant strides in various fields, backed by advancements in diverse methodologies, hardware development, interdisciplinary research, and trials across different domains[1] - [5].

Allergens, typically proteins capable of triggering adverse immune responses, represent a significant public health challenge. To accurately identify allergen proteins, we introduce Applm (Allergen Prediction with Protein Language Models), a computational framework that leverages the 100-billion parameter xTrimoPGLM protein language model. We show that Applm consistently outperforms seven state-of-the-art methods in a diverse set of tasks that closely resemble difficult real-world scenarios. These include identifying novel allergens that lack similar examples in the training set, differentiating between allergens and non-allergens among homologs with high sequence similarity, and assessing functional consequences of mutations that create few changes to the protein sequences. Our analysis confirms that xTrimoPGLM, originally trained on one trillion tokens to capture general protein sequence characteristics, is crucial for Applm's performance by detecting important differences among protein sequences. In addition to providing Applm as open-source software, we also provide our carefully curated benchmark datasets to facilitate future research.

A local-valley (LV) centered approach to assessing the quality of sampling from Restricted Boltzmann Machines (RBMs) was applied to the latest generation of the D-Wave quantum annealer. D-Wave and Gibbs samples from a classically trained RBM were obtained at conditions relevant to the contrastive-divergence-based RBM learning. The samples were compared for the number of the LVs to which they belonged and the energy of the corresponding local minima. No significant (desirable) increase in the number of the LVs has been achieved by decreasing the D-Wave annealing time. At any training epoch, the states sampled by the D-Wave belonged to a somewhat higher number of LVs than in the Gibbs sampling. However, many of those LVs found by the two techniques differed. For high-probability sampled states, the two techniques were (unfavorably) less complementary and more overlapping. Nevertheless, many potentially "important" local minima, i.e., those having intermediate, even if not high, probability values, were found by only one of the two sampling techniques while missed by the other. The two techniques overlapped less at later than earlier training epochs, which is precisely the stage of the training when modest improvements to the sampling quality could make meaningful differences for the RBM trainability. The results of this work may explain the failure of previous investigations to achieve substantial (or any) improvement when using D-Wave-based sampling. However, the results reveal some potential for improvement, e.g., using a combined classical-quantum approach.