Clinical notes contain valuable, context-rich information, but their unstructured format introduces several challenges, including unintended biases (e.g., gender or racial bias), and poor generalization across clinical settings (e.g., models trained on one EHR system may perform poorly on another due to format differences) and poor interpretability. To address these issues, we present ClinStructor, a pipeline that leverages large language models (LLMs) to convert clinical free-text into structured, task-specific question-answer pairs prior to predictive modeling. Our method substantially enhances transparency and controllability and only leads to a modest reduction in predictive performance (a 2-3% drop in AUC), compared to direct fine-tuning, on the ICU mortality prediction task. ClinStructor lays a strong foundation for building reliable, interpretable, and generalizable machine learning models in clinical environments.

Story understanding and analysis have long been challenging areas within Natural Language Understanding. Automated narrative analysis requires deep computational semantic representations along with syntactic processing. Moreover, the large volume of narrative data demands automated semantic analysis and computational learning rather than manual analytical approaches. In this paper, we propose a framework that analyzes the sentiment arcs of movie scripts and performs extended analysis related to the context of the characters involved. The framework enables the extraction of high-level and low-level concepts conveyed through the narrative. Using dictionary-based sentiment analysis, our approach applies a custom lexicon built with the LabMTsimple storylab module. The custom lexicon is based on the Valence, Arousal, and Dominance scores from the NRC-VAD dataset. Furthermore, the framework advances the analysis by clustering similar sentiment plots using Wards hierarchical clustering technique. Experimental evaluation on a movie dataset shows that the resulting analysis is helpful to consumers and readers when selecting a narrative or story.

Speech quality and intelligibility are significantly degraded in noisy environments. This paper presents a novel transformer-based learning framework to address the single-channel noise suppression problem for real-time applications. Although existing deep learning networks have shown remarkable improvements in handling stationary noise, their performance often diminishes in real-world environments characterized by non-stationary noise (e.g., dog barking, baby crying). The proposed dual-input acoustic-image feature fusion using a hybrid ViT framework effectively models both temporal and spectral dependencies in noisy signals. Designed for real-world audio environments, the proposed framework is computationally lightweight and suitable for implementation on embedded devices. T o evaluate its effectiveness, four standard and commonly used quality measurements, namely PESQ, STOI, Seg SNR, and LLR, are utilized. Experimental results obtained using the Librispeech dataset as the clean speech source and the Ur-banSound8K and Google Audioset datasets as the noise sources, demonstrate that the proposed method significantly improves noise reduction, speech intelligibility, and perceptual quality compared to the noisy input signal, achieving performance close to the clean reference.

Systematic logistics, conveyance amenities and facilities as well as warehousing information play a key role in fostering profitable development in a supply chain. The aim of transformation in industries is the improvement of the resiliency regarding the supply chain. The resiliency policies are required for companies to affect the collaboration with logistics service providers positively. The decrement of air pollutant emissions is a persistent advantage of the efficient management of logistics and transportation in supply chain. The management of shipment type is a significant factor in analyzing the sustainability of logistics and supply chain. An automatic approach to predict the shipment type, logistics delay and traffic status are required to improve the efficiency of the supply chain management. A hybrid graphsage network (H-GSN) is proposed in this paper for multi-task purpose of logistics management in a supply chain. The shipment type, shipment status, traffic status, logistics ID and logistics delay are the objectives in this article regarding three different databases including DataCo, Shipping and Smart Logistcis available on Kaggle as supply chain logistics databases. The average accuracy of 97.8% and 100% are acquired for 10 kinds of logistics ID and 3 types of traffic status prediction in Smart Logistics dataset. The average accuracy of 98.7% and 99.4% are obtained for shipment type prediction in DataCo and logistics delay in Shipping database, respectively. The evaluation metrics for different logistics scenarios confirm the efficiency of the proposed method to improve the resilience and sustainability of the supply chain.

Device-to-device variability in experimental noise critically impacts reproducibility, especially in automated, high-throughput systems like additive manufacturing farms. While manageable in small labs, such variability can escalate into serious risks at larger scales, such as architectural 3D printing, where noise may cause structural or economic failures. This contribution presents a noise-aware decision-making algorithm that quantifies and models device-specific noise profiles to manage variability adap-tively. It uses distributional analysis and pairwise divergence metrics with clustering to choose between single-device and robust multi-device Bayesian optimization strategies. Unlike conventional methods that assume homogeneous devices or generic robustness, this framework explicitly leverages inter-device differences to enhance performance, reproducibility, and efficiency. An experimental case study involving three nominally identical 3D printers (same brand, model, and close serial numbers) demonstrates reduced redundancy, lower resource usage, and improved reliability. Overall, this framework establishes a paradigm for precision-and resource-aware optimization in scalable, automated experimental platforms. Introduction Recent advances in automation technologies have revolutionized scientific research, particularly in fields that rely on high-throughput experimentation.

Diagnosing the root causes of Quality of Experience (QoE) degradations in operational mobile networks is challenging due to complex cross-layer interactions among kernel performance indicators (KPIs) and the scarcity of reliable expert annotations. Although rule-based heuristics can generate labels at scale, they are noisy and coarse-grained, limiting the accuracy of purely data-driven approaches. To address this, we propose DK-Root, a joint data-and-knowledge-driven framework that unifies scalable weak supervision with precise expert guidance for robust root-cause analysis. DK-Root first pretrains an encoder via contrastive representation learning using abundant rule-based labels while explicitly denoising their noise through a supervised contrastive objective. To supply task-faithful data augmentation, we introduce a class-conditional diffusion model that generates KPIs sequences preserving root-cause semantics, and by controlling reverse diffusion steps, it produces weak and strong augmentations that improve intra-class compactness and inter-class separability. Finally, the encoder and the lightweight classifier are jointly fine-tuned with scarce expert-verified labels to sharpen decision boundaries. Extensive experiments on a real-world, operator-grade dataset demonstrate state-of-the-art accuracy, with DK-Root surpassing traditional ML and recent semi-supervised time-series methods. Ablations confirm the necessity of the conditional diffusion augmentation and the pretrain-finetune design, validating both representation quality and classification gains.

Effectively modeling multimodal spatial omics data is critical for understanding tissue complexity and underlying biological mechanisms. While spatial transcriptomics, proteomics, and epigenomics capture molecular features, they lack pathological morphological context. Integrating these omics with histopathological images is therefore essential for comprehensive disease tissue analysis. However, substantial heterogeneity across omics, imaging, and spatial modalities poses significant challenges. Naive fusion of semantically distinct sources often leads to ambiguous representations. Additionally, the resolution mismatch between high-resolution histology images and lower-resolution sequencing spots complicates spatial alignment. Biological perturbations during sample preparation further distort modality-specific signals, hindering accurate integration. To address these challenges, we propose Graph-guided Representation of Omics and Vision with Expert Regulation for Adaptive Spatial Multi-omics Fusion (GROVER), a novel framework for adaptive integration of spatial multi-omics data. GROVER leverages a Graph Convolutional Network encoder based on Kolmogorov-Arnold Networks to capture the nonlinear dependencies between each modality and its associated spatial structure, thereby producing expressive, modality-specific embeddings. To align these representations, we introduce a spot-feature-pair contrastive learning strategy that explicitly optimizes the correspondence across modalities at each spot. Furthermore, we design a dynamic expert routing mechanism that adaptively selects informative modalities for each spot while suppressing noisy or low-quality inputs. Experiments on real-world spatial omics datasets demonstrate that GROVER outperforms state-of-the-art baselines, providing a robust and reliable solution for multimodal integration.

Single-cell data analysis seeks to characterize cellular heterogeneity based on high-dimensional gene expression profiles. Conventional approaches represent each cell as a vector in Euclidean space, which limits their ability to capture intrinsic correlations and multiscale geometric structures. We propose a multiscale framework based on Grassmann manifolds that integrates machine learning with subspace geometry for single-cell data analysis. By generating embeddings under multiple representation scales, the framework combines their features from different geometric views into a unified Grassmann manifold. A power-based scale sampling function is introduced to control the selection of scales and balance in- formation across resolutions. Experiments on nine benchmark single-cell RNA-seq datasets demonstrate that the proposed approach effectively preserves meaningful structures and provides stable clustering performance, particularly for small to medium-sized datasets. These results suggest that Grassmann manifolds offer a coherent and informative foundation for analyzing single cell data.

Understanding 3D scene-level affordances from natural language instructions is essential for enabling embodied agents to interact meaningfully in complex environments. However, this task remains challenging due to the need for semantic reasoning and spatial grounding. Existing methods mainly focus on object-level affordances or merely lift 2D predictions to 3D, neglecting rich geometric structure information in point clouds and incurring high computational costs. To address these limitations, we introduce Task-Aware 3D Scene-level Affordance segmentation (T ASA), a novel geometry-optimized framework that jointly leverages 2D semantic cues and 3D geometric reasoning in a coarse-to-fine manner. To improve the affordance detection efficiency, T ASA features a task-aware 2D affordance detection module to identify manipulable points from language and visual inputs, guiding the selection of task-relevant views. To fully exploit 3D geometric information, a 3D affordance refinement module is proposed to integrate 2D semantic priors with local 3D geometry, resulting in accurate and spatially coherent 3D affor-dance masks. Experiments on SceneFun3D demonstrate that T ASA significantly outperforms the baselines in both accuracy and efficiency in scene-level affordance segmentation.

Pre-trained models have demonstrated exceptional generalization capabilities in time-series forecasting; however, adapting them to evolving data distributions remains a significant challenge. A key hurdle lies in accessing the original training data, as fine-tuning solely on new data often leads to catastrophic forgetting. To address this issue, we propose Replay Tuning (R-Tuning), a novel framework designed for the continual adaptation of pre-trained time-series models. R-Tuning constructs a unified latent space that captures both prior and current task knowledge through a frequency-aware replay strategy. Specifically, it augments model-generated samples via wavelet-based decomposition across multiple frequency bands, generating trend-preserving and fusion-enhanced variants to improve representation diversity and replay efficiency. To further reduce reliance on synthetic samples, R-Tuning introduces a latent consistency constraint that aligns new representations with the prior task space. This constraint guides joint optimization within a compact and semantically coherent latent space, ensuring robust knowledge retention and adaptation. Extensive experimental results demonstrate the superiority of R-Tuning, which reduces MAE and MSE by up to 46.9% and 46.8%, respectively, on new tasks, while preserving prior knowledge with gains of up to 5.7% and 6.0% on old tasks. Notably, under few-shot settings, R-Tuning outperforms all state-of-the-art baselines even when synthetic proxy samples account for only 5% of the new task dataset.