The rapid proliferation of Internet of Medical Things (IoMT) devices in healthcare has introduced unique cybersecurity challenges, primarily due to the diverse communication protocols and critical nature of these devices This research aims to develop an advanced, real-time anomaly detection framework tailored for IoMT network traffic, leveraging AI/ML models and the CICIoMT2024 dataset By integrating multi-protocol (MQTT, WiFi), attack-specific (DoS, DDoS), time-series (active/idle states), and device-specific (Bluetooth) data, our study captures a comprehensive range of IoMT interactions As part of our data analysis, various machine learning techniques are employed which include an ensemble model using XGBoost for improved performance against specific attack types, sequential models comprised of LSTM and CNN-LSTM that leverage time dependencies, and unsupervised models such as Autoencoders and Isolation Forest that are good in general anomaly detection The results of the experiment prove with an ensemble model lowers false positive rates and reduced detections.

Agents in real-world scenarios like automated driving deal with uncertainty in their environment, in particular due to perceptual uncertainty. Although, reinforcement learning is dedicated to autonomous decision-making under uncertainty these algorithms are typically not informed about the uncertainty currently contained in their environment. On the other hand, uncertainty estimation for perception itself is typically directly evaluated in the perception domain, e.g., in terms of false positive detection rates or calibration errors based on camera images. Its use for deciding on goal-oriented actions remains largely unstudied. In this paper, we investigate how an agent's behavior is influenced by an uncertain perception and how this behavior changes if information about this uncertainty is available. Therefore, we consider a proxy task, where the agent is rewarded for driving a route as fast as possible without colliding with other road users. For controlled experiments, we introduce uncertainty in the observation space by perturbing the perception of the given agent while informing the latter. Our experiments show that an unreliable observation space modeled by a perturbed perception leads to a defensive driving behavior of the agent. Furthermore, when adding the information about the current uncertainty directly to the observation space, the agent adapts to the specific situation and in general accomplishes its task faster while, at the same time, accounting for risks.

Virus-like particles (VLPs) are valuable for vaccine development due to their immune-triggering properties. Understanding their stoichiometry, the number of protein subunits to form a VLP, is critical for vaccine optimisation. However, current experimental methods to determine stoichiometry are time-consuming and require highly purified proteins. To efficiently classify stoichiometry classes in proteins, we curate a new dataset and propose an interpretable, data-driven pipeline leveraging linear machine learning models. We also explore the impact of feature encoding on model performance and interpretability, as well as methods to identify key protein sequence features influencing classification. The evaluation of our pipeline demonstrates that it can classify stoichiometry while revealing protein features that possibly influence VLP assembly. The data and code used in this work are publicly available at https://github.com/Shef-AIRE/StoicIML.

Studying systematic weaknesses of DNNs has gained prominence in the last few years with the rising focus on building safe AI systems. Slice discovery methods (SDMs) are prominent algorithmic approaches for finding such systematic weaknesses. They identify top-k semantically coherent slices/subsets of data where a DNN-under-test has low performance. For being directly useful, e.g., as evidences in a safety argumentation, slices should be aligned with human-understandable (safety-relevant) dimensions, which, for example, are defined by safety and domain experts as parts of the operational design domain (ODD). While straightforward for structured data, the lack of semantic metadata makes these investigations challenging for unstructured data. Therefore, we propose a complete workflow which combines contemporary foundation models with algorithms for combinatorial search that consider structured data and DNN errors for finding systematic weaknesses in images. In contrast to existing approaches, ours identifies weak slices that are in line with predefined human-understandable dimensions. As the workflow includes foundation models, its intermediate and final results may not always be exact. Therefore, we build into our workflow an approach to address the impact of noisy metadata. We evaluate our approach w.r.t. its quality on four popular computer vision datasets, including autonomous driving datasets like Cityscapes, BDD100k, and RailSem19, while using multiple state-of-the-art models as DNNs-under-test.

Optical Coherence Tomography (OCT) provides high-resolution cross-sectional images useful for diagnosing various diseases, but their distinct characteristics from natural images raise questions about whether large-scale pre-training on datasets like ImageNet is always beneficial. In this paper, we investigate the impact of ImageNet-based pre-training on Vision Transformer (ViT) performance for OCT image classification across different dataset sizes. Our experiments cover four-category retinal pathologies (CNV, DME, Drusen, Normal). Results suggest that while pre-training can accelerate convergence and potentially offer better performance in smaller datasets, training from scratch may achieve comparable or even superior accuracy when sufficient OCT data is available. Our findings highlight the importance of matching domain characteristics in pre-training and call for further study on large-scale OCT-specific pre-training.

The rapid growth of the Internet of Things (IoT) has revolutionized industries, enabling unprecedented connectivity and functionality. However, this expansion also increases vulnerabilities, exposing IoT networks to increasingly sophisticated cyberattacks. Intrusion Detection Systems (IDS) are crucial for mitigating these threats, and recent advancements in Machine Learning (ML) offer promising avenues for improvement. This research explores a hybrid approach, combining several standalone ML models such as Random Forest (RF), XGBoost, K-Nearest Neighbors (KNN), and AdaBoost, in a voting-based hybrid classifier for effective IoT intrusion detection. This ensemble method leverages the strengths of individual algorithms to enhance accuracy and address challenges related to data complexity and scalability. Using the widely-cited IoT-23 dataset, a prominent benchmark in IoT cybersecurity research, we evaluate our hybrid classifiers for both binary and multi-class intrusion detection problems, ensuring a fair comparison with existing literature. Results demonstrate that our proposed hybrid models, designed for robustness and scalability, outperform standalone approaches in IoT environments. This work contributes to the development of advanced, intelligent IDS frameworks capable of addressing evolving cyber threats.

Speech foundation models trained at a massive scale, both in terms of model and data size, result in robust systems capable of performing multiple speech tasks, including automatic speech recognition (ASR). These models transcend language and domain barriers, yet effectively measuring their performance remains a challenge. Traditional metrics like word error rate (WER) and character error rate (CER) are commonly used to evaluate ASR performance but often fail to reflect transcription quality in critical contexts, particularly when detecting fabricated outputs. This phenomenon, known as hallucination, is especially concerning in high-stakes domains such as healthcare, legal, and aviation, where errors can have severe consequences. In our work, we address this gap by investigating hallucination in ASR models. We examine how factors such as distribution shifts, model size, and model architecture influence the hallucination error rate (HER), a metric we introduce to quantify hallucinations. Our analysis of 20 ASR models reveals \numinsights~key insights: (1) High WERs can mask low hallucination rates, while low WERs may conceal dangerous hallucinations. (2) Synthetic noise, both adversarial and common perturbations like white noise, pitch shift, and time stretching, increase HER. (3) Distribution shift correlates strongly with HER ($\alpha = 0.91$). Our findings highlight the importance of incorporating HER alongside traditional metrics like WER to better assess ASR model performance, particularly in high-stakes domains.

Drug discovery is crucial for identifying candidate drugs for various diseases.However, its low success rate often results in a scarcity of annotations, posing a few-shot learning problem. Existing methods primarily focus on single-scale features, overlooking the hierarchical molecular structures that determine different molecular properties. To address these issues, we introduce Universal Matching Networks (UniMatch), a dual matching framework that integrates explicit hierarchical molecular matching with implicit task-level matching via meta-learning, bridging multi-level molecular representations and task-level generalization. Specifically, our approach explicitly captures structural features across multiple levels, such as atoms, substructures, and molecules, via hierarchical pooling and matching, facilitating precise molecular representation and comparison. Additionally, we employ a meta-learning strategy for implicit task-level matching, allowing the model to capture shared patterns across tasks and quickly adapt to new ones. This unified matching framework ensures effective molecular alignment while leveraging shared meta-knowledge for fast adaptation. Our experimental results demonstrate that UniMatch outperforms state-of-the-art methods on the MoleculeNet and FS-Mol benchmarks, achieving improvements of 2.87% in AUROC and 6.52% in delta AUPRC. UniMatch also shows excellent generalization ability on the Meta-MolNet benchmark.

The classical kernel ridge regression problem aims to find the best fit for the output $Y$ as a function of the input data $X\in \mathbb{R}^d$, with a fixed choice of regularization term imposed by a given choice of a reproducing kernel Hilbert space, such as a Sobolev space. Here we consider a generalization of the kernel ridge regression problem, by introducing an extra matrix parameter $U$, which aims to detect the scale parameters and the feature variables in the data, and thereby improve the efficiency of kernel ridge regression. This naturally leads to a nonlinear variational problem to optimize the choice of $U$. We study various foundational mathematical aspects of this variational problem, and in particular how this behaves in the presence of multiscale structures in the data.

Surface anomaly classification is critical for manufacturing system fault diagnosis and quality control. However, the following challenges always hinder accurate anomaly classification in practice: (i) Anomaly patterns exhibit intra-class variation and inter-class similarity, presenting challenges in the accurate classification of each sample. (ii) Despite the predefined classes, new types of anomalies can occur during production that require to be detected accurately. (iii) Anomalous data is rare in manufacturing processes, leading to limited data for model learning. To tackle the above challenges simultaneously, this paper proposes a novel deep subspace learning-based 3D anomaly classification model. Specifically, starting from a lightweight encoder to extract the latent representations, we model each class as a subspace to account for the intra-class variation, while promoting distinct subspaces of different classes to tackle the inter-class similarity. Moreover, the explicit modeling of subspaces offers the capability to detect out-of-distribution samples, i.e., new types of anomalies, and the regularization effect with much fewer learnable parameters of our proposed subspace classifier, compared to the popular Multi-Layer Perceptions (MLPs). Extensive numerical experiments demonstrate our method achieves better anomaly classification results than benchmark methods, and can effectively identify the new types of anomalies.