Colon cancer also known as Colorectal cancer, is one of the most malignant types of cancer worldwide. Early-stage detection of colon cancer is highly crucial to prevent its deterioration. This research presents a hybrid multi-scale deep learning architecture that synergizes capsule networks, graph attention mechanisms, transformer modules, and residual learning to advance colon cancer classification on the Lung and Colon Cancer Histopathological Image Dataset (LC25000) dataset. The proposed model in this paper utilizes the HG-TNet model that introduces a hybrid architecture that joins strength points in transformers and convolutional neural networks to capture multi-scale features in histopathological images. Mainly, a transformer branch extracts global contextual bonds by partitioning the image into patches by convolution-based patch embedding and then processing these patches through a transformer encoder. Analogously, a dedicated CNN branch captures fine-grained, local details through successive Incorporation these diverse features, combined with a self-supervised rotation prediction objective, produce a robust diagnostic representation that surpasses standard architectures in performance. Results show better performance not only in accuracy or loss function but also in these algorithms by utilizing capsule networks to preserve spatial orders and realize how each element individually combines and forms whole structures.

This study explores the deployment of three machine learning (ML) approaches for real-time prediction of glucose, lactate, and ammonium concentrations in cell culture processes, using Raman spectroscopy as input features. The research addresses challenges associated with limited data availability and process variability, providing a comparative analysis of pretrained models, just-in-time learning (JITL), and online learning algorithms. Two industrial case studies are presented to evaluate the impact of varying bioprocess conditions on model performance. The findings highlight the specific conditions under which pretrained models demonstrate superior predictive accuracy and identify scenarios where JITL or online learning approaches are more effective for adaptive process monitoring. This study also highlights the critical importance of updating the deployed models/agents with the latest offline analytical measurements during bioreactor operations to maintain the model performance against the changes in cell growth behaviours and operating conditions throughout the bioreactor run. Additionally, the study confirms the usefulness of a simple mixture-of-experts framework in achieving enhanced accuracy and robustness for real-time predictions of metabolite concentrations based on Raman spectral data. These insights contribute to the development of robust strategies for the efficient deployment of ML models in dynamic and changing biomanufacturing environments.

Class imbalance remains a fundamental challenge in machine learning, with traditional solutions often creating as many problems as they solve. We demonstrate that group-aware threshold calibration--setting different decision thresholds for different demographic groups--provides superior robustness compared to synthetic data generation methods. Through extensive experiments, we show that group-specific thresholds achieve 1.5-4% higher balanced accuracy than SMOTE and CT-GAN augmented models while improving worst-group balanced accuracy. Unlike single-threshold approaches that apply one cutoff across all groups, our group-aware method optimizes the Pareto frontier between balanced accuracy and worst-group balanced accuracy, enabling fine-grained control over group-level performance. Critically, we find that applying group thresholds to synthetically augmented data yields minimal additional benefit, suggesting these approaches are fundamentally redundant. Our results span seven model families including linear, tree-based, instance-based, and boosting methods, confirming that group-aware threshold calibration offers a simpler, more interpretable, and more effective solution to class imbalance.

We present a novel deep generative semi-supervised framework for credit card fraud detection, formulated as time series classification task. As financial transaction data streams grow in scale and complexity, traditional methods often require large labeled datasets, struggle with time series of irregular sampling frequencies and varying sequence lengths. To address these challenges, we extend conditional Generative Adversarial Networks (GANs) for targeted data augmentation, integrate Bayesian inference to obtain predictive distributions and quantify uncertainty, and leverage log-signatures for robust feature encoding of transaction histories. We introduce a novel Wasserstein distance-based loss to align generated and real unlabeled samples while simultaneously maximizing classification accuracy on labeled data. Our approach is evaluated on the BankSim dataset, a widely used simulator for credit card transaction data, under varying proportions of labeled samples, demonstrating consistent improvements over benchmarks in both global statistical and domain-specific metrics. These findings highlight the effectiveness of GAN-driven semi-supervised learning with log-signatures for irregularly sampled time series and emphasize the importance of uncertainty-aware predictions.

Time Series Anomaly Detection metrics serve as crucial tools for model evaluation. However, existing metrics suffer from several limitations: insufficient discriminative power, strong hyperparameter dependency, sensitivity to perturbations, and high computational overhead. This paper introduces Confidence-Consistency Evaluation (CCE), a novel evaluation metric that simultaneously measures prediction confidence and uncertainty consistency. By employing Bayesian estimation to quantify the uncertainty of anomaly scores, we construct both global and event-level confidence and consistency scores for model predictions, resulting in a concise CCE metric. Theoretically and experimentally, we demonstrate that CCE possesses strict boundedness, Lipschitz robustness against score perturbations, and linear time complexity $\mathcal{O}(n)$. Furthermore, we establish RankEval, a benchmark for comparing the ranking capabilities of various metrics. RankEval represents the first standardized and reproducible evaluation pipeline that enables objective comparison of evaluation metrics. Both CCE and RankEval implementations are fully open-source.

Mental disorders are clinically significant patterns of behavior that are associated with stress and/or impairment in social, occupational, or family activities. People suffering from such disorders are often misjudged and poorly diagnosed due to a lack of visible symptoms compared to other health complications. During emergency situations, identifying psychiatric issues is that's why challenging but highly required to save patients. In this paper, we have conducted research on how traditional machine learning and large language models (LLM) can assess these psychiatric patients based on their behavioral patterns to provide a diagnostic assessment. Data from emergency psychiatric patients were collected from a rescue station in Germany. Various machine learning models, including Llama 3.1, were used with rescue patient data to assess if the predictive capabilities of the models can serve as an efficient tool for identifying patients with unhealthy mental disorders, especially in rescue cases.

Industrial-scale battery management involves various types of tasks, such as estimation, prediction, and system-level diagnostics. Each task employs distinct data across temporal scales, sensor resolutions, and data channels. Building task-specific methods requires a great deal of data and engineering effort, which limits the scalability of intelligent battery management. Here we present the Flexible Masked Autoencoder (FMAE), a flexible pretraining framework that can learn with missing battery data channels and capture inter-correlations across data snippets. FMAE learns unified battery representations from heterogeneous data and can be adopted by different tasks with minimal data and engineering efforts. Experimentally, FMAE consistently outperforms all task-specific methods across five battery management tasks with eleven battery datasets. On remaining life prediction tasks, FMAE uses 50 times less inference data while maintaining state-of-the-art results. Moreover, when real-world data lack certain information, such as system voltage, FMAE can still be applied with marginal performance impact, achieving comparable results with the best hand-crafted features. FMAE demonstrates a practical route to a flexible, data-efficient model that simplifies real-world multi-task management of dynamical systems.

Vehicle safety assessment is crucial for consumer information and regulatory oversight. The New Car Assessment Program (NCAP) assigns standardized safety ratings, which traditionally emphasize passive safety measures but now include active safety technologies such as Advanced Driver-Assistance Systems (ADAS). It is crucial to understand how these various systems interact empirically. This study explores whether particular ADAS features like Forward Collision Warning, Lane Departure Warning, Crash Imminent Braking, and Blind Spot Detection, together with established vehicle attributes (e.g., Curb Weight, Model Year, Vehicle Type, Drive Train), can reliably predict a vehicle's likelihood of earning the highest (5-star) overall NCAP rating. Using a publicly available dataset derived from NCAP reports that contain approximately 5,128 vehicle variants spanning model years 2011-2025, we compared four different machine learning models: logistic regression, random forest, gradient boosting, and support vector classifier (SVC) using a 5-fold stratified cross-validation approach. The two best-performing algorithms (random forest and gradient boost) were hyperparameter optimized using RandomizedSearchCV. Analysis of feature importance showed that basic vehicle characteristics, specifically curb weight and model year, dominated predictive capability, contributing more than 55% of the feature relevance of the Random Forest model. However, the inclusion of ADAS features also provided meaningful predictive contributions. The optimized Random Forest model achieved robust results on a held-out test set, with an accuracy of 89.18% and a ROC AUC of 0.9586. This research reveals the use of machine learning to analyze large-scale NCAP data and highlights the combined predictive importance of both established vehicle parameters and modern ADAS features to achieve top safety ratings.

--T alent identification plays a critical role in promoting student development. However, traditional approaches often rely on manual processes or focus narrowly on academic achievement, and typically delaying intervention until the higher education stage. This oversight overlooks diverse non-academic talents and misses opportunities for early intervention. T o address this gap, this study introduces T alentPredictor, a novel semi-supervised multi-modal neural network that combines Transformer, LSTM, and ANN architectures. This model is designed to predict seven different talent types--academic, sport, art, leadership, service, technology, and others--in secondary school students within an offline educational setting. Drawing on existing offline educational data from 1,041 local secondary students, T alentPredictor overcomes the limitations of traditional talent identification methods. By clustering various award records into talent categories and extracting features from students' diverse learning behaviors, it achieves high prediction accuracy (0.908 classification accuracy, 0.908 ROCAUC). This demonstrates the potential of machine learning to identify diverse talents early in student development. ALENT is a critical component in human society. It is indispensable to the development of societies and the competitiveness of countries. Last but not least, talent is always in high demand. Thus, nurturing talent is the top priority for every part of the earth, and in it, talent identification is the foundation, as you must have a target individual to nurture talent. Traditional talent identification aims to give students tests that exceed their current level. For example, give grade eight students college admissions tests and use the result of the tough test as a talent score.

Semi-structured tables, widely used in real-world applications (e.g., financial reports, medical records, transactional orders), often involve flexible and complex layouts (e.g., hierarchical headers and merged cells). These tables generally rely on human analysts to interpret table layouts and answer relevant natural language questions, which is costly and inefficient. To automate the procedure, existing methods face significant challenges. First, methods like NL2SQL require converting semi-structured tables into structured ones, which often causes substantial information loss. Second, methods like NL2Code and multi-modal LLM QA struggle to understand the complex layouts of semi-structured tables and cannot accurately answer corresponding questions. To this end, we propose ST-Raptor, a tree-based framework for semi-structured table question answering using large language models. First, we introduce the Hierarchical Orthogonal Tree (HO-Tree), a structural model that captures complex semi-structured table layouts, along with an effective algorithm for constructing the tree. Second, we define a set of basic tree operations to guide LLMs in executing common QA tasks. Given a user question, ST-Raptor decomposes it into simpler sub-questions, generates corresponding tree operation pipelines, and conducts operation-table alignment for accurate pipeline execution. Third, we incorporate a two-stage verification mechanism: forward validation checks the correctness of execution steps, while backward validation evaluates answer reliability by reconstructing queries from predicted answers. To benchmark the performance, we present SSTQA, a dataset of 764 questions over 102 real-world semi-structured tables. Experiments show that ST-Raptor outperforms nine baselines by up to 20% in answer accuracy. The code is available at https://github.com/weAIDB/ST-Raptor.