Introduction. Dermoscopy aids melanoma triage, yet image-only AI often ignores patient metadata (age, sex, site) and the physical scale needed for geometric analysis. We present GraphDerm, a population-graph framework that fuses imaging, millimeter-scale calibration, and metadata for multiclass dermoscopic classification, to the best of our knowledge the first ISIC-scale application of GNNs to dermoscopy. Methods. We curate ISIC 2018/2019, synthesize ruler-embedded images with exact masks, and train U-Nets (SE-ResNet-18) for lesion and ruler segmentation. Pixels-per-millimeter are regressed from the ruler-mask two-point correlation via a lightweight 1D-CNN. From lesion masks we compute real-scale descriptors (area, perimeter, radius of gyration). Node features use EfficientNet-B3; edges encode metadata/geometry similarity (fully weighted or thresholded). A spectral GNN performs semi-supervised node classification; an image-only ANN is the baseline. Results. Ruler and lesion segmentation reach Dice 0.904 and 0.908; scale regression attains MAE 1.5 px (RMSE 6.6). The graph attains AUC 0.9812, with a thresholded variant using about 25% of edges preserving AUC 0.9788 (vs. 0.9440 for the image-only baseline); per-class AUCs typically fall in the 0.97-0.99 range. Conclusion. Unifying calibrated scale, lesion geometry, and metadata in a population graph yields substantial gains over image-only pipelines on ISIC-2019. Sparser graphs retain near-optimal accuracy, suggesting efficient deployment. Scale-aware, graph-based AI is a promising direction for dermoscopic decision support; future work will refine learned edge semantics and evaluate on broader curated benchmarks.

Controlling environmental conditions and monitoring plant status in greenhouses is critical to promptly making appropriate management decisions aimed at promoting crop production. The primary objective of this research study was to develop and test a smart aeroponic greenhouse on an experimental scale where the status of Geranium plant and environmental conditions are continuously monitored through the integration of the internet of things (IoT) and artificial intelligence (AI). An IoT-based platform was developed to control the environmental conditions of plants more efficiently and provide insights to users to make informed management decisions. In addition, we developed an AI-based disease detection framework using VGG-19, InceptionResNetV2, and InceptionV3 algorithms to analyze the images captured periodically after an intentional inoculation. The performance of the AI framework was compared with an expert's evaluation of disease status. Preliminary results showed that the IoT system implemented in the greenhouse environment is able to publish data such as temperature, humidity, water flow, and volume of charge tanks online continuously to users and adjust the controlled parameters to provide an optimal growth environment for the plants. Furthermore, the results of the AI framework demonstrate that the VGG-19 algorithm was able to identify drought stress and rust leaves from healthy leaves with the highest accuracy, 92% among the other algorithms.

The rise of large language models (LLMs) has made natural language-driven route planning an emerging research area that encompasses rich user objectives. Current research exhibits two distinct approaches: direct route planning using LLM-as-Agent and graph-based searching strategies. However, LLMs in the former approach struggle to handle extensive map data, while the latter shows limited capability in understanding natural language preferences. Additionally, a more critical challenge arises from the highly heterogeneous and unpredictable spatio-temporal distribution of users across the globe. In this paper, we introduce a novel LLM-Assisted route Planning (LLMAP) system that employs an LLM-as-Parser to comprehend natural language, identify tasks, and extract user preferences and recognize task dependencies, coupled with a Multi-Step Graph construction with iterative Search (MSGS) algorithm as the underlying solver for optimal route finding. Our multi-objective optimization approach adaptively tunes objective weights to maximize points of interest (POI) quality and task completion rate while minimizing route distance, subject to three key constraints: user time limits, POI opening hours, and task dependencies. We conduct extensive experiments using 1,000 routing prompts sampled with varying complexity across 14 countries and 27 cities worldwide. The results demonstrate that our approach achieves superior performance with guarantees across multiple constraints.

This work proposes a Variational Physics-Informed Neural Network (VPINN) framework that integrates the Petrov-Galerkin formulation with deep neural networks (DNNs) for solving one-dimensional singularly perturbed boundary value problems (BVPs) and parabolic partial differential equations (PDEs) involving one or two small parameters. The method adopts a nonlinear approximation in which the trial space is defined by neural network functions, while the test space is constructed from hat functions. The weak formulation is constructed using localized test functions, with interface penalty terms introduced to enhance numerical stability and accurately capture boundary layers. Dirichlet boundary conditions are imposed via hard constraints, and source terms are computed using automatic differentiation. Numerical experiments on benchmark problems demonstrate the effectiveness of the proposed method, showing significantly improved accuracy in both the $L_2$ and maximum norms compared to the standard VPINN approach for one-dimensional singularly perturbed differential equations (SPDEs).

This paper proposes the MT-DQN model, which integrates a Transformer, Temporal Graph Neural Network (TGNN), and Deep Q-Network (DQN) to address the challenges of predicting user behavior and optimizing recommendation strategies in short-video environments. Experiments demonstrated that MT-DQN consistently outperforms traditional concatenated models, such as Concat-Modal, achieving an average F1-score improvement of 10.97% and an average NDCG@5 improvement of 8.3%. Compared to the classic reinforcement learning model Vanilla-DQN, MT-DQN reduces MSE by 34.8% and MAE by 26.5%. Nonetheless, we also recognize challenges in deploying MT-DQN in real-world scenarios, such as its computational cost and latency sensitivity during online inference, which will be addressed through future architectural optimization.

We introduce Genome-Factory, an integrated Python library for tuning, deploying, and interpreting genomic models. Our core contribution is to simplify and unify the workflow for genomic model development: data collection, model tuning, inference, benchmarking, and interpretability. For data collection, Genome-Factory offers an automated pipeline to download genomic sequences and preprocess them. It also includes quality control, such as GC content normalization. For model tuning, Genome-Factory supports three approaches: full-parameter, low-rank adaptation, and adapter-based fine-tuning. It is compatible with a wide range of genomic models. For inference, Genome-Factory enables both embedding extraction and DNA sequence generation. For benchmarking, we include two existing benchmarks and provide a flexible interface for users to incorporate additional benchmarks. For interpretability, Genome-Factory introduces the first open-source biological interpreter based on a sparse auto-encoder. This module disentangles embeddings into sparse, near-monosemantic latent units and links them to interpretable genomic features by regressing on external readouts. To improve accessibility, Genome-Factory features both a zero-code command-line interface and a user-friendly web interface. We validate the utility of Genome-Factory across three dimensions: (i) Compatibility with diverse models and fine-tuning methods; (ii) Benchmarking downstream performance using two open-source benchmarks; (iii) Biological interpretation of learned representations with DNABERT-2. These results highlight its end-to-end usability and practical value for real-world genomic analysis.

The simplicity Bias (SB) of neural networks, i.e.\ their tendency to represent simple functions, is a key factor in their generalization capabilities. Recent studies show that an excessive SB may harm performance on complex tasks, and the need for this bias varies across tasks. Many of these studies focus on simple models or synthetic tasks. It remains challenging to measure the SB in large models and little is known about the relevance of the SB to various image classification tasks. In this paper, we investigate the relationship between the SB in CLIP models and their performance across image classification tasks. First, we theoretically analyze the potential limitation of existing measures of complexity that have been used to characterize small models. To address this, we propose a frequency-aware measure capturing finer-grained SB differences. We validate this measure on CLIP models subjected to two recent SB-modulation methods, demonstrating that it is more informative and consistent than previous measures. Second, we examine the relation between the SB of those models and their performance across a range of image classification tasks, including zero-shot and fine-tuning settings. These experiments reveal a range of behaviors. For example, a stronger SB correlates with a better performance on OOD generalization than on adversarial robustness. These results highlight the benefits of aligning a model's inductive biases with the characteristics of the target task.

Large multimodal models (LMMs) encode universal physical laws observed during training, such as momentum conservation, as parametric knowledge. It allows LMMs to answer physical reasoning queries, such as the outcome of a potential collision event from visual input. However, since parametric knowledge includes only the physical laws seen during training, it is insufficient for reasoning when the inference scenario violates these physical laws. In contrast, humans possess the skill to adapt their physical reasoning to unseen physical environments from a few visual examples. This ability, which we refer to as inductive physical reasoning, is indispensable for LMMs if they are to replace human agents in safety-critical applications. Despite its importance, existing visual benchmarks evaluate only the parametric knowledge in LMMs, and not inductive physical reasoning. To this end, we propose InPhyRe, the first visual question answering benchmark to measure inductive physical reasoning in LMMs. InPhyRe evaluates LMMs on their ability to predict the outcome of collision events in algorithmically generated synthetic collision videos. By inspecting 13 LMMs, InPhyRe informs us that (1) LMMs struggle to apply their limited parametric knowledge about universal physical laws to reasoning, (2) inductive physical reasoning in LMMs is weak when demonstration samples violate universal physical laws, and (3) inductive physical reasoning in LMMs suffers from language bias and largely ignores the visual inputs, questioning the trustworthiness of LMMs regarding visual inputs.

The Quantum-Inspired Stacked Integrated Concept Graph Model (QISICGM) is an innovative machine learning framework that harnesses quantum-inspired techniques to predict diabetes risk with exceptional accuracy and efficiency. Utilizing the PIMA Indians Diabetes dataset augmented with 2,000 synthetic samples to mitigate class imbalance (total: 2,768 samples, 1,949 positives), QISICGM integrates a self-improving concept graph with a stacked ensemble comprising Random Forests (RF), Extra Trees (ET), transformers, convolutional neural networks (CNNs), and feed-forward neural networks (FFNNs). This approach achieves an out-of-fold (OOF) F1 score of 0.8933 and an AUC of 0.8699, outperforming traditional methods. Quantum inspired elements, such as phase feature mapping and neighborhood sequence modeling, enrich feature representations, enabling CPU-efficient inference at 8.5 rows per second. This paper presents a detailed architecture, theoretical foundations, code insights, and performance evaluations, including visualizations from the outputs subfolder. The open-source implementation (v1.0.0) is available at https://github.com/keninayoung/QISICGM, positioning QISICGM as a potential benchmark for AI-assisted clinical triage in diabetes and beyond. Ultimately, this work emphasizes trustworthy AI through calibration, interpretability, and open-source reproducibility.

Non-invasive glucose monitoring remains a long-standing challenge in biomedical sensing, with the potential to transform diabetes management by eliminating painful finger pricks, reducing consumable costs, and enabling real-time glucose tracking. Despite decades of research, no solution has matched the accuracy and reliability of invasive methods in real-world deployment. Near-infrared (NIR) spectroscopy -- leveraging glucose's absorption features in the 850-1150 nm range -- remains the most promising modality, but progress has stalled due to the problem's intrinsic complexity. At its core, non-invasive glucose monitoring is an ill-posed inverse problem. The NIR signal measured at the skin surface reflects a convoluted mixture of tissue scattering, overlapping spectral absorption from water, hemoglobin, and fat, and variations in skin thickness, perfusion, and melanin content. These physiological variables are compounded by hardware noise (e.g., ADC quantization, LED instability, photodiode dark current) and environmental drift (e.g., temperature, humidity, ambient light). In the field, these effects suppress glucose-NIR correlation to ρ 0.21, rendering many lab-trained models ineffective. 1