This work examines how three different image-based methods, VGG16, ViT-B/16, and CoAtNet-Tiny, perform in identifying depression, schizophrenia, and healthy controls using daily actigraphy records. Wrist-worn activity signals from the Psykose and Depresjon datasets were converted into 30 48 images and evaluated through a three-fold subject-wise split. Although all methods fitted the training data well, their behaviour on unseen data differed. VGG16 improved steadily but often settled at lower accuracy. ViT-B/16 reached strong results in some runs, but its performance shifted noticeably from fold to fold. CoAtNet-Tiny stood out as the most reliable, recording the highest average accuracy and the most stable curves across folds. It also produced the strongest precision, recall, and F1-scores, particularly for the underrepresented depression and schizophrenia classes. Overall, the findings indicate that CoAtNet-Tiny performed most consistently on the actigraphy images, while VGG16 and ViT-B/16 yielded mixed results. These observations suggest that certain hybrid designs may be especially suited for mental-health work that relies on actigraphy-derived images. I. Introduction Mental health disorders such as depression and schizophrenia constitute a significant and growing global health challenge, with profound impacts on individuals, families, and healthcare systems worldwide. According to the World Health Organization, depression affects over 280 million people.

As COVID-19 transitions into an endemic disease that remains constantly present in the population at a stable level, monitoring its prevalence without invasive measures becomes increasingly important. In this paper, we present a deep neural network estimator for the COVID-19 daily case count based on wastewater surveillance data and other confounding factors. This work builds upon the study by Jiang, Kolozsvary, and Li (2024), which connects the COVID-19 case counts with testing data collected early in the pandemic. Using the COVID-19 testing data and the wastewater surveillance data during the period when both data were highly reliable, one can train an artificial neural network that learns the nonlinear relation between the COVID-19 daily case count and the wastewater viral RNA concentration. From a machine learning perspective, the main challenge lies in addressing temporal feature reliability, as the training data has different reliability over different time periods.

We propose SemImage, a novel method for representing a text document as a two-dimensional semantic image to be processed by convolutional neural networks (CNNs). In a SemImage, each word is represented as a pixel in a 2D image: rows correspond to sentences and an additional boundary row is inserted between sentences to mark semantic transitions. Each pixel is not a typical RGB value but a vector in a disentangled HSV color space, encoding different linguistic features: the Hue with two components H_cos and H_sin to account for circularity encodes the topic, Saturation encodes the sentiment, and Value encodes intensity or certainty. We enforce this disentanglement via a multi-task learning framework: a ColorMapper network maps each word embedding to the HSV space, and auxiliary supervision is applied to the Hue and Saturation channels to predict topic and sentiment labels, alongside the main task objective. The insertion of dynamically computed boundary rows between sentences yields sharp visual boundaries in the image when consecutive sentences are semantically dissimilar, effectively making paragraph breaks salient. We integrate SemImage with standard 2D CNNs (e.g., ResNet) for document classification. Experiments on multi-label datasets (with both topic and sentiment annotations) and single-label benchmarks demonstrate that SemImage can achieve competitive or better accuracy than strong text classification baselines (including BERT and hierarchical attention networks) while offering enhanced interpretability. An ablation study confirms the importance of the multi-channel HSV representation and the dynamic boundary rows. Finally, we present visualizations of SemImage that qualitatively reveal clear patterns corresponding to topic shifts and sentiment changes in the generated image, suggesting that our representation makes these linguistic features visible to both humans and machines.

In recent times, denoising diffusion probabilistic models (DPMs) have proven to show significant success in medical image generation and denoising, while also serving as powerful representation learners for downstream tasks such as segmentation. However, their effectiveness in segmentation is limited by the need for detailed pixel-wise annotations, which are expensive, time-consuming, and require expert knowledge--a significant bottleneck in real-world clinical applications. In order to mitigate this limitation of label-efficiency, we propose a fast and efficient model named FastTextDiff, a diffusion-based segmentation model that integrates medical text annotations to enhance semantic representations. Our approach leverages ModernBERT [3], a transformer-based language model capable of processing long medical text sequences, to establish a strong connection between textual annotations and semantic meaning in medical imaging. ModernBERT can efficiently encode clinical knowledge for directing segmentation tasks since it has been trained on both MIMIC-III [19] and MIMIC-IV. Label-efficient segmentation with enhanced performance is made possible by cross-modal attention processes, which enable smooth interaction between visual and textual modalities. This study validates ModernBERT as a quick and scalable substitute for Clinical BioBERT [4] in diffusion-based segmentation pipelines [2] and demonstrates the promise of multi-modal techniques for medical image analysis.

Accurate single cell detection in brightfield microscopy is crucial for biological research, yet data scarcity and annotation bottlenecks limit the progress of deep learning methods. We investigate the use of unconditional models to generate synthetic brightfield microscopy images and evaluate their impact on object detection performance. A U-Net based diffusion model was trained and used to create datasets with varying ratios of synthetic and real images. Experiments with YOLOv8, YOLOv9 and RT-DETR reveal that training with synthetic data can achieve improved detection accuracies (at minimal costs). A human expert survey demonstrates the high realism of generated images, with experts not capable to distinguish them from real microscopy images (accuracy 50%). Our findings suggest that diffusion-based synthetic data generation is a promising avenue for augmenting real datasets in microscopy image analysis, reducing the reliance on extensive manual annotation and potentially improving the robustness of cell detection models.

We propose a technique to assist in converting a reference layout of an analog circuit into the procedural layout generator by efficiently reusing available generators for sub-cell creation. The proposed convolutional neural network (CNN) model automatically detects sub-cells that can be generated by available generator scripts in the library, and suggests using them in the hierarchically correct places of the generator software. In experiments, the CNN model examined sub-cells of a high-speed wireline receiver that has a total of 4,885 sub-cell instances including different 145 sub-cell designs. The CNN model classified the sub-cell instances into 51 generatable and one not-generatable classes. One not-generatable class indicates that no available generator can generate the classified sub-cell. The CNN model achieved 99.3% precision in examining the 145 different sub-cell designs. The CNN model greatly reduced the examination time to 18 seconds from 88 minutes required in manual examination. Also, the proposed CNN model could correctly classify unfamiliar sub-cells that are very different from the training dataset.

Deep Neural Networks (DNNs) continue to grow in complexity with Large Language Models (LLMs) incorporating vast numbers of parameters. Handling these parameters efficiently in traditional accelerators is limited by data-transmission bottlenecks, motivating Compute-in-Memory (CiM) architectures that integrate computation within or near memory to reduce data movement. Recent work has explored CiM designs using Floating-Point (FP) and Integer (INT) operations. FP computations typically deliver higher output quality due to their wider dynamic range and precision, benefiting precision-sensitive Generative AI applications. These include models such as LLMs, thus driving advancements in FP-CiM accelerators. However, the vulnerability of FP-CiM to hardware faults remains underexplored, posing a major reliability concern in mission-critical settings. To address this gap, we systematically analyze hardware fault effects in FP-CiM by introducing bit-flip faults at key computational stages, including digital multipliers, CiM memory cells, and digital adder trees. Experiments with Convolutional Neural Networks (CNNs) such as AlexNet and state-of-the-art LLMs including LLaMA-3.2-1B and Qwen-0.3B-Base reveal how faults at each stage affect inference accuracy. Notably, a single adder fault can reduce LLM accuracy to 0%. Based on these insights, we propose a fault-resilient design, SafeCiM, that mitigates fault impact far better than a naive FP-CiM with a pre-alignment stage. For example, with 4096 MAC units, SafeCiM reduces accuracy degradation by up to 49x for a single adder fault compared to the baseline FP-CiM architecture.

Studying how embeddings are organized in space not only enhances model interpretability but also uncovers factors that drive downstream task performance. In this paper, we present a comprehensive analysis of topological and geometric measures across a wide set of text embedding models and datasets. We find a high degree of redundancy among these measures and observe that individual metrics often fail to sufficiently differentiate embedding spaces. Building on these insights, we introduce Unified Topological Signatures (UTS), a holistic framework for characterizing embedding spaces. We show that UTS can predict model-specific properties and reveal similarities driven by model architecture. Further, we demonstrate the utility of our method by linking topological structure to ranking effectiveness and accurately predicting document retrievability. We find that a holistic, multi-attribute perspective is essential to understanding and leveraging the geometry of text embeddings.

Large language model (LLM) inference often suffers from high decoding latency and limited scalability across heterogeneous edge-cloud environments. Existing speculative decoding (SD) techniques accelerate token generation but remain confined to single-node execution. We propose DSD, a distributed speculative decoding framework that extends SD to multi-device deployments through coordinated draft-target execution. Given the lack of prior work on simulating this paradigm, we first introduce DSD-Sim, a discrete-event simulator that captures network, batching, and scheduling dynamics. Building on insights from DSD-Sim, we further design an Adaptive Window Control (AWC) policy that dynamically adjusts speculation window size to optimize throughput. Experiments across diverse workloads show that DSD achieves up to 1.1x speedup and 9.7% higher throughput over existing SD baselines, enabling agile and scalable LLM serving across edge and cloud.

This study proposes Tool-RoCo, a novel benchmark for evaluating large language models (LLMs) in long-term multi-agent cooperation based on RoCo, a multi-robot cooperative benchmark. Recent research on LLM-based multi-agent systems has relied on predefined orchestration, while ignoring agent autonomy. Tool-RoCo treats other agents as tools and introduces cooperative tools, leveraging tool usage to evaluate multi-agent cooperation and self-organization. Tool usage means that each agent (LLM) selects a tool from a candidate set based on the current state, receives feedback, and adjusts its selection in subsequent rounds. To evaluate different autonomy levels, we propose four LLM paradigms: (1) centralized cooperation, where a single LLM allocates tools to all agents; (2) centralized self-organization, where a central LLM autonomously activates agents while keeping others inactive; (3) decentralized cooperation, where each agent has its own LLM and calls tools based on local information; and (4) self-organization, where a randomly chosen initial agent can request collaboration, activating additional agents via tool calls. Tool-RoCo includes three multi-robot tasks, SORT, P ACK, and CABINET, to measure format and parameter accuracy and agent coordination through tool usage. The results using several LLMs showed that cooperative tools accounted for only 7.09% of all tools, indicating that LLM-based agents rarely invoked others as assistants. Moreover, activation tools accounted for 96.42%, suggesting that current LLMs tend to maintain active agents while seldom deactivating them for adaptive coordination. Tool-RoCo provides a systematic benchmark to evaluate LLM autonomy and cooperation in multi-agent tasks.