This work proposes a wavelet-based physics-informed quantum neural network framework to efficiently address multiscale partial differential equations that involve sharp gradients, stiffness, rapid local variations, and highly oscillatory behavior. Traditional physics-informed neural networks (PINNs) have demonstrated substantial potential in solving differential equations, and their quantum counterparts, quantum-PINNs, exhibit enhanced representational capacity with fewer trainable parameters. However, both approaches face notable challenges in accurately solving the multiscale features. Furthermore, their reliance on automatic differentiation for constructing loss functions introduces considerable computational overhead, resulting in longer training times. To overcome these challenges, we developed a wavelet-accelerated physics-informed quantum neural network that eliminates the need for automatic differentiation, significantly reducing computational complexity. The proposed framework incorporates the multiresolution property of wavelets within the quantum neural network architecture, thereby enhancing the network's ability to effectively capture both local and global features of multiscale problems. Numerical experiments demonstrate that our proposed method achieves superior accuracy while requiring less than five percent of the trainable parameters compared to classical wavelet-based PINNs, resulting in faster convergence. Moreover, it offers three to five times speed-up compared to existing quantum PINNs, highlighting the potential of the proposed approach for solving challenging multiscale and oscillatory problems efficiently.

This paper presents a Spatiotemporal Tube (STT)-based control framework for general control-affine MIMO nonlinear pure-feedback systems with unknown dynamics to satisfy prescribed time reach-avoid-stay tasks under external disturbances. The STT is defined as a time-varying ball, whose center and radius are jointly approximated by a Physics-Informed Neural Network (PINN). The constraints governing the STT are first formulated as loss functions of the PINN, and a training algorithm is proposed to minimize the overall violation. The PINN being trained on certain collocation points, we propose a Lipschitz-based validity condition to formally verify that the learned PINN satisfies the conditions over the continuous time horizon. Building on the learned STT representation, an approximation-free closed-form controller is defined to guarantee satisfaction of the T-RAS specification. Finally, the effectiveness and scalability of the framework are validated through two case studies involving a mobile robot and an aerial vehicle navigating through cluttered environments.

A novel deep hybrid Residual-SwinCA-Net segmentation framework is proposed in the study for addressing such challenges by extracting locally correlated and robust features, incorporating residual CNN modules. Furthermore, for learning global dependencies, Swin Transformer blocks are customized using internal residual pathways, which reinforce gradient stability, refine local patterns, and facilitate global feature fusion. Formerly, for enhancing tissue continuity, ultrasound noise suppressions, and accentuating fine structural transitions Laplacian-of-Gaussian regional operator is applied, and for maintaining the morphological integrity of malignant lesion contours, a boundary-oriented operator has been incorporated. Subsequently, a contraction strategy was applied stage-wise by progressively reducing features-map progressively for capturing scale invariance and enhancing the robustness of structural variability. In addition, each decoder level prior augmentation integrates a new Multi-Scale Channel Attention and Squeezing (MSCAS) module. The MSCAS selectively emphasizes encoder salient maps, retains discriminative global context, and complementary local structures with minimal computational cost while suppressing redundant activations. Finally, the Pixel-Attention module encodes class-relevant spatial cues by adaptively weighing malignant lesion pixels while suppressing background interference. The Residual-SwinCA-Net and existing CNNs/ViTs techniques have been implemented on the publicly available BUSI dataset. The proposed Residual-SwinCA-Net framework outperformed and achieved 99.29% mean accuracy, 98.74% IoU, and 0.9041 Dice for breast lesion segmentation. The proposed Residual-SwinCA-Net framework improves the BUSI lesion diagnostic performance and strengthens timely clinical decision-making.

This paper presents a mathematically rigorous framework for brain-inspired representation learning founded on the interplay between persistent topological structures and cohomological flows. Neural computation is reformulated as the evolution of cochain maps over dynamic simplicial complexes, enabling representations that capture invariants across temporal, spatial, and functional brain states. The proposed architecture integrates algebraic topology with differential geometry to construct cohomological operators that generalize gradient-based learning within a homological landscape. Synthetic data with controlled topological signatures and real neural datasets are jointly analyzed using persistent homology, sheaf cohomology, and spectral Laplacians to quantify stability, continuity, and structural preservation. Empirical results demonstrate that the model achieves superior manifold consistency and noise resilience compared to graph neural and manifold-based deep architectures, establishing a coherent mathematical foundation for topology-driven representation learning.

Decoupled weight decay, solely responsible for the performance advantage of AdamW over Adam, has long been set to proportional to learning rate γ without questioning. To the contrary, we find that eliminating the contribution of the perpendicular component of the update to the weight norm leads to little change to the training dynamics. For adaptive gradient methods such as SGD with momentum (Sutskever et al., 2013) and Adam (Kingma & Ba, 2015), weight decay is no longer equivalent to L Nevertheless, Defazio (2025) presents experiments on Llama 3 architecture (Grattafiori et al., 2024) in which most layers are not immediately followed by normalization. It states that "we consider every linear layer as normalized, excluding the output layer of the network" for the purpose of applying such corrected weight decay, and AdamC results in more stable weight and gradient norms than the AdamW baseline regardless. Consider the "Renormalized" AdamW optimizer above (Algorithm 1) which eliminates the contribution of u We train a variant of ViT -S/16 based on the setup described in Beyer et al. (2022) on the ImageNet-1k dataset (Russakovsky et al., 2015) for 90 epochs and instead observe almost no differences in relevant metrics (Figure 1).

Mobile phones are the most ubiquitous end devices, generating vast amounts of human-authored data and serving as the primary platform for end-side applications. As high-quality public data for large language models (LLMs) approaches exhaustion, on-device fine-tuning provides an opportunity to leverage private user data while preserving privacy. However, existing approaches are predominantly simulation-based or rely on IoT devices and PCs, leaving commodity mobile phones largely unexplored. A key gap is the absence of an open-source framework that enables practical LLM fine-tuning on mobile phones. We present MobileFineTuner, a unified open-source framework that enables end-to-end LLM fine-tuning directly on commodity mobile phones. MobileFineTuner is designed for efficiency, scalability, and usability, supporting full-parameters fine-tuning (Full-FT) and parameter-efficient fine-tuning (PEFT). To address the memory and energy limitations inherent to mobile phones, we introduce system-level optimizations including parameter sharding, gradient accumulation, and energy-aware computation scheduling. We demonstrate the practicality of MobileFineTuner by fine-tuning GPT-2, Gemma 3, and Qwen 2.5 on real mobile phones. Extensive experiments and ablation studies validate the effectiveness of the proposed optimizations and establish MobileFineTuner as a viable foundation for future research on on-device LLM training.

We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles. Our system effectively increases access to structured clinical trial data by 83.8% compared to relying on ClinicalTrials.gov alone, with potential to make access easier for patients, clinicians, researchers, and policymakers, advancing evidence-based medicine. ClinicalTrialsHub uses large language models such as GPT-5.1 and Gemini-3-Pro to enhance accessibility. The platform automatically parses full-text research articles to extract structured trial information, translates user queries into structured database searches, and provides an attributed question-answering system that generates evidence-grounded answers linked to specific source sentences. We demonstrate its utility through a user study involving clinicians, clinical researchers, and PhD students of pharmaceutical sciences and nursing, and a systematic automatic evaluation of its information extraction and question answering capabilities.

Medical Large Language Models (LLMs) are increasingly deployed for clinical decision support across diverse specialties, yet systematic evaluation of their robustness to adversarial misuse and privacy leakage remains inaccessible to most researchers. Existing security benchmarks require GPU clusters, commercial API access, or protected health data -- barriers that limit community participation in this critical research area. We propose a practical, fully reproducible framework for evaluating medical AI security under realistic resource constraints. Our framework design covers multiple medical specialties stratified by clinical risk -- from high-risk domains such as emergency medicine and psychiatry to general practice -- addressing jailbreaking attacks (role-playing, authority impersonation, multi-turn manipulation) and privacy extraction attacks. All evaluation utilizes synthetic patient records requiring no IRB approval. The framework is designed to run entirely on consumer CPU hardware using freely available models, eliminating cost barriers. We present the framework specification including threat models, data generation methodology, evaluation protocols, and scoring rubrics. This proposal establishes a foundation for comparative security assessment of medical-specialist models and defense mechanisms, advancing the broader goal of ensuring safe and trustworthy medical AI systems.

In our prior work, LayerPipe, we had introduced an approach to accelerate training of convolutional, fully connected, and spiking neural networks by overlapping forward and backward computation. However, despite empirical success, a principled understanding of how much gradient delay needs to be introduced at each layer to achieve desired level of pipelining was not addressed. This paper, LayerPipe2, fills that gap by formally deriving LayerPipe using variable delayed gradient adaptation and retiming. We identify where delays may be legally inserted and show that the required amount of delay follows directly from the network structure where inner layers require fewer delays and outer layers require longer delays. When pipelining is applied at every layer, the amount of delay depends only on the number of remaining downstream stages. When layers are pipelined in groups, all layers in the group share the same assignment of delays. These insights not only explain previously observed scheduling patterns but also expose an often overlooked challenge that pipelining implicitly requires storage of historical weights. We overcome this storage bottleneck by developing a pipeline--aware moving average that reconstructs the required past states rather than storing them explicitly. This reduces memory cost without sacrificing the accuracy guarantees that makes pipelined learning viable. The result is a principled framework that illustrates how to construct LayerPipe architectures, predicts their delay requirements, and mitigates their storage burden, thereby enabling scalable pipelined training with controlled communication computation tradeoffs.

The future of UAV interaction systems is evolving from engineer-driven to user-driven, aiming to replace traditional predefined Human-UAV Interaction designs. This shift focuses on enabling more personalized task planning and design, thereby achieving a higher quality of interaction experience and greater flexibility, which can be used in many fileds, such as agriculture, aerial photography, logistics, and environmental monitoring. However, due to the lack of a common language between users and the UAVs, such interactions are often difficult to be achieved. The developments of Large Language Models possess the ability to understand nature languages and Robots' (UAVs') behaviors, marking the possibility of personalized Human-UAV Interaction. Recently, some HUI frameworks based on LLMs have been proposed, but they commonly suffer from difficulties in mixed task planning and execution, leading to low adaptability in complex scenarios. In this paper, we propose a novel dual-agent HUI framework. This framework constructs two independent LLM agents (a task planning agent, and an execution agent) and applies different Prompt Engineering to separately handle the understanding, planning, and execution of tasks. To verify the effectiveness and performance of the framework, we have built a task database covering four typical application scenarios of UAVs and quantified the performance of the HUI framework using three independent metrics. Meanwhile different LLM models are selected to control the UAVs with compared performance. Our user study experimental results demonstrate that the framework improves the smoothness of HUI and the flexibility of task execution in the tasks scenario we set up, effectively meeting users' personalized needs.