The solution of inverse problems is of fundamental interest in medical and astronomical imaging, geophysics as well as engineering and life sciences. Recent advances were made by using methods from machine learning, in particular deep neural networks. Most of these methods require a huge amount of (paired) data and computer capacity to train the networks, which often may not be available. Our paper addresses the issue of learning from small data sets by taking patches of very few images into account. We focus on the combination of model-based and data-driven methods by approximating just the image prior, also known as regularizer in the variational model. We review two methodically different approaches, namely optimizing the maximum log-likelihood of the patch distribution, and penalizing Wasserstein-like discrepancies of whole empirical patch distributions. From the point of view of Bayesian inverse problems, we show how we can achieve uncertainty quantification by approximating the posterior using Langevin Monte Carlo methods. We demonstrate the power of the methods in computed tomography, image super-resolution, and inpainting. Indeed, the approach provides also high-quality results in zero-shot super-resolution, where only a low-resolution image is available. The paper is accompanied by a GitHub repository containing implementations of all methods as well as data examples so that the reader can get their own insight into the performance.

Multi-access Edge Computing (MEC) can be implemented together with Open Radio Access Network (O-RAN) over commodity platforms to offer low-cost deployment and bring the services closer to end-users. In this paper, a joint O-RAN/MEC orchestration using a Bayesian deep reinforcement learning (RL)-based framework is proposed that jointly controls the O-RAN functional splits, the allocated resources and hosting locations of the O-RAN/MEC services across geo-distributed platforms, and the routing for each O-RAN/MEC data flow. The goal is to minimize the long-term overall network operation cost and maximize the MEC performance criterion while adapting possibly time-varying O-RAN/MEC demands and resource availability. This orchestration problem is formulated as Markov decision process (MDP). However, the system consists of multiple BSs that share the same resources and serve heterogeneous demands, where their parameters have non-trivial relations. Consequently, finding the exact model of the underlying system is impractical, and the formulated MDP renders in a large state space with multi-dimensional discrete action. To address such modeling and dimensionality issues, a novel model-free RL agent is proposed for our solution framework. The agent is built from Double Deep Q-network (DDQN) that tackles the large state space and is then incorporated with action branching, an action decomposition method that effectively addresses the multi-dimensional discrete action with linear increase complexity. Further, an efficient exploration-exploitation strategy under a Bayesian framework using Thomson sampling is proposed to improve the learning performance and expedite its convergence. Trace-driven simulations are performed using an O-RAN-compliant model. The results show that our approach is data-efficient (i.e., converges faster) and increases the returned reward by 32\% than its non-Bayesian version.

Machine learning and data mining techniques are utiized for enhancement of the security of any network. Researchers used machine learning for pattern detection, anomaly detection, dynamic policy setting, etc. The methods allow the program to learn from data and make decisions without human intervention, consuming a huge training period and computation power. This paper discusses a novel technique to predict an upcoming attack in a network based on several data parameters. The dataset is continuous in real-time implementation. The proposed model comprises dataset pre-processing, and training, followed by the testing phase. Based on the results of the testing phase, the best model is selected using which, event class which may lead to an attack is extracted. The event statistics are used for attack

The challenge of producing accurate statistics while respecting the privacy of the individuals in a sample is an important area of research. We study minimax lower bounds for classes of differentially private estimators. In particular, we show how to characterize the power of a statistical test under differential privacy in a plug-and-play fashion by solving an appropriate transport problem. With specific coupling constructions, this observation allows us to derive Le Cam-type and Fano-type inequalities not only for regular definitions of differential privacy but also for those based on Renyi divergence. We then proceed to illustrate our results on three simple, fully worked out examples. In particular, we show that the problem class has a huge importance on the provable degradation of utility due to privacy. In certain scenarios, we show that maintaining privacy results in a noticeable reduction in performance only when the level of privacy protection is very high. Conversely, for other problems, even a modest level of privacy protection can lead to a significant decrease in performance. Finally, we demonstrate that the DP-SGLD algorithm, a private convex solver, can be employed for maximum likelihood estimation with a high degree of confidence, as it provides near-optimal results with respect to both the size of the sample and the level of privacy protection. This algorithm is applicable to a broad range of parametric estimation procedures, including exponential families.

In the domain of medical imaging, many supervised learning based methods for segmentation face several challenges such as high variability in annotations from multiple experts, paucity of labelled data and class imbalanced datasets. These issues may result in segmentations that lack the requisite precision for clinical analysis and can be misleadingly overconfident without associated uncertainty quantification. We propose the PULASki for biomedical image segmentation that accurately captures variability in expert annotations, even in small datasets. Our approach makes use of an improved loss function based on statistical distances in a conditional variational autoencoder structure (Probabilistic UNet), which improves learning of the conditional decoder compared to the standard cross-entropy particularly in class imbalanced problems. We analyse our method for two structurally different segmentation tasks (intracranial vessel and multiple sclerosis (MS) lesion) and compare our results to four well-established baselines in terms of quantitative metrics and qualitative output. Empirical results demonstrate the PULASKi method outperforms all baselines at the 5\% significance level. The generated segmentations are shown to be much more anatomically plausible than in the 2D case, particularly for the vessel task. Our method can also be applied to a wide range of multi-label segmentation tasks and and is useful for downstream tasks such as hemodynamic modelling (computational fluid dynamics and data assimilation), clinical decision making, and treatment planning.

Graph contrastive learning (GCL) aims to align the positive features while differentiating the negative features in the latent space by minimizing a pair-wise contrastive loss. As the embodiment of an outstanding discriminative unsupervised graph representation learning approach, GCL achieves impressive successes in various graph benchmarks. However, such an approach falls short of recognizing the topology isomorphism of graphs, resulting in that graphs with relatively homogeneous node features cannot be sufficiently discriminated. By revisiting classic graph topology recognition works, we disclose that the corresponding expertise intuitively complements GCL methods. To this end, we propose a novel hierarchical topology isomorphism expertise embedded graph contrastive learning, which introduces knowledge distillations to empower GCL models to learn the hierarchical topology isomorphism expertise, including the graph-tier and subgraph-tier. On top of this, the proposed method holds the feature of plug-and-play, and we empirically demonstrate that the proposed method is universal to multiple state-of-the-art GCL models. The solid theoretical analyses are further provided to prove that compared with conventional GCL methods, our method acquires the tighter upper bound of Bayes classification error. We conduct extensive experiments on real-world benchmarks to exhibit the performance superiority of our method over candidate GCL methods, e.g., for the real-world graph representation learning experiments, the proposed method beats the state-of-the-art method by 0.23% on unsupervised representation learning setting, 0.43% on transfer learning setting. Our code is available at https://github.com/jyf123/HTML.

This study explores the efficacy of a multi-perspective hybrid neural network (HNN) for scoring student responses in science education with an analytic rubric. We compared the accuracy of the HNN model with four ML approaches (BERT, AACR, Naive Bayes, and Logistic Regression). The results have shown that HHN achieved 8%, 3%, 1%, and 0.12% higher accuracy than Naive Bayes, Logistic Regression, AACR, and BERT, respectively, for five scoring aspects (p<0.001). The overall HNN's perceived accuracy (M = 96.23%, SD = 1.45%) is comparable to the (training and inference) expensive BERT model's accuracy (M = 96.12%, SD = 1.52%). We also have observed that HNN is x2 more efficient in training and inferencing than BERT and has comparable efficiency to the lightweight but less accurate Naive Bayes model. Our study confirmed the accuracy and efficiency of using HNN to score students' science writing automatically.

This work studies the learning process over social networks under partial and random information sharing. In traditional social learning models, agents exchange full belief information with each other while trying to infer the true state of nature. We study the case where agents share information about only one hypothesis, namely, the trending topic, which can be randomly changing at every iteration. We show that agents can learn the true hypothesis even if they do not discuss it, at rates comparable to traditional social learning. We also show that using one's own belief as a prior for estimating the neighbors' non-transmitted beliefs might create opinion clusters that prevent learning with full confidence. This phenomenon occurs when a single hypothesis corresponding to the truth is exchanged exclusively during all times. Such a practice, however, avoids the complete rejection of the truth under any information exchange procedure -- something that could happen if priors were uniform.

We propose a physics-informed machine learning method for uncertainty quantification in high-dimensional inverse problems. In this method, the states and parameters of partial differential equations (PDEs) are approximated with truncated conditional Karhunen-Lo\`eve expansions (CKLEs), which, by construction, match the measurements of the respective variables. The maximum a posteriori (MAP) solution of the inverse problem is formulated as a minimization problem over CKLE coefficients where the loss function is the sum of the norm of PDE residuals and the $\ell_2$ regularization term. This MAP formulation is known as the physics-informed CKLE (PICKLE) method. Uncertainty in the inverse solution is quantified in terms of the posterior distribution of CKLE coefficients, and we sample the posterior by solving a randomized PICKLE minimization problem, formulated by adding zero-mean Gaussian perturbations in the PICKLE loss function. We call the proposed approach the randomized PICKLE (rPICKLE) method. For linear and low-dimensional nonlinear problems (15 CKLE parameters), we show analytically and through comparison with Hamiltonian Monte Carlo (HMC) that the rPICKLE posterior converges to the true posterior given by the Bayes rule. For high-dimensional non-linear problems with 2000 CKLE parameters, we numerically demonstrate that rPICKLE posteriors are highly informative--they provide mean estimates with an accuracy comparable to the estimates given by the MAP solution and the confidence interval that mostly covers the reference solution. We are not able to obtain the HMC posterior to validate rPICKLE's convergence to the true posterior due to the HMC's prohibitive computational cost for the considered high-dimensional problems. Our results demonstrate the advantages of rPICKLE over HMC for approximately sampling high-dimensional posterior distributions subject to physics constraints.

Reinforcement learning-based large language models, such as ChatGPT, are believed to have potential to aid human experts in many domains, including healthcare. There is, however, little work on ChatGPT's ability to perform a key task in healthcare: formal, probabilistic medical diagnostic reasoning. This type of reasoning is used, for example, to update a pre-test probability to a post-test probability. In this work, we probe ChatGPT's ability to perform this task. In particular, we ask ChatGPT to give examples of how to use Bayes rule for medical diagnosis. Our prompts range from queries that use terminology from pure probability (e.g., requests for a posterior of A given B and C) to queries that use terminology from medical diagnosis (e.g., requests for a posterior probability of Covid given a test result and cough). We show how the introduction of medical variable names leads to an increase in the number of errors that ChatGPT makes. Given our results, we also show how one can use prompt engineering to facilitate ChatGPT's partial avoidance of these errors. We discuss our results in light of recent commentaries on sensitivity and specificity. We also discuss how our results might inform new research directions for large language models.