Algorithmic Information Theory has inspired intractable constructions of general intelligence (AGI), and undiscovered tractable approximations are likely feasible. Reinforcement Learning (RL), the dominant paradigm by which an agent might learn to solve arbitrary solvable problems, gives an agent a dangerous incentive: to gain arbitrary "power" in order to intervene in the provision of their own reward. We review the arguments that generally intelligent algorithmic-information-theoretic reinforcement learners such as Hutter's (2005) AIXI would seek arbitrary power, including over us. Then, using an information-theoretic exploration schedule, and a setup inspired by causal influence theory, we present a variant of AIXI which learns to not seek arbitrary power; we call it "unambitious". We show that our agent learns to accrue reward at least as well as a human mentor, while relying on that mentor with diminishing probability. And given a formal assumption that we probe empirically, we show that eventually, the agent's world-model incorporates the following true fact: intervening in the "outside world" will have no effect on reward acquisition; hence, it has no incentive to shape the outside world.

This chapter provides a summary of recent developments harnessing the data revolution to realize the science goals of Gravitational Wave Astrophysics. This is an exciting journey that is powered by the renaissance of artificial intelligence, and a new generation of researchers that are willing to embrace disruptive advances in innovative computing and signal processing tools. In this chapter, machine learning refers to a class of algorithms that can learn from data to solve new problems without being explicitly re-programmed. While traditional machine learning algorithms, e.g., random forests, nearest neighbors, etc., have been used successfully in many applications, they are limited in their ability to process raw data, usually requiring time-consuming feature engineering to preprocess data into a suitable representation for each application. On the other hand, deep learning algorithms can learn patterns from unstructured data, finding useful representations and automatically extracting relevant features for each application. The ability of deep learning to deal with poorly defined abstractions and problems has led to major advances in image recognition, speech, computer vision applications, robotics, among others [1]. The following sections describe a few noteworthy applications of modern machine learning for gravitational wave modeling, detection and inference. It is the expectation that by the time this chapter is published, the ongoing developments at the interface of artificial intelligence and extreme-scale computing will have leapt forward, making this chapter a reminiscence of a fast-paced, evolving field of research. The chapter concludes with a summary of recent applications at the interface of deep learning and high performance computing to address computational grand challenges in Gravitational Wave Astrophysics.

At last year's conference, we presented approaches for learning Bayesian networks from a combination of prior knowledge and statistical data. These approaches were presented in two papers: one addressing domains containing only discrete variables (Heckerman et al., 1994), and the other addressing domains containing continuous variables related by an unknown multivariate-Gaussian distribution (Geiger and Heckerman, 1994). Unfortunately, these presentations were substantially different, making the parallels between the two methods difficult to appreciate. In this paper, we unify the two approaches. In particular, we abstract our previous assumptions of likelihood equivalence, parameter modularity, and parameter independence such that they are appropriate for discrete and Gaussian domains (as well as other domains). Using these assumptions, we derive a domain-independent Bayesian scoring metric. We then use this general metric in combination with well-known statistical facts about the Dirichlet and normal-Wishart distributions to derive our metrics for discrete and Gaussian domains. In addition, we provide simple proofs that these assumptions are consistent for both domains.

Biopharmaceutical manufacturing is a rapidly growing industry with impact in virtually all branches of medicine. Biomanufacturing processes require close monitoring and control, in the presence of complex bioprocess dynamics with many interdependent factors, as well as extremely limited data due to the high cost and long duration of experiments. We develop a novel model-based reinforcement learning framework that can achieve human-level control in low-data environments. The model uses a probabilistic knowledge graph to capture causal interdependencies between factors in the underlying stochastic decision process, leveraging information from existing kinetic models from different unit operations while incorporating real-world experimental data. We then present a computationally efficient, provably convergent stochastic gradient method for policy optimization. Validation is conducted on a realistic application with a multi-dimensional, continuous state variable.

We develop simple methods for constructing likelihoods and parameter priors for learning about the parameters and structure of a Bayesian network. In particular, we introduce several assumptions that permit the construction of likelihoods and parameter priors for a large number of Bayesian-network structures from a small set of assessments. The most notable assumption is that of likelihood equivalence, which says that data can not help to discriminate network structures that encode the same assertions of conditional independence. We describe the constructions that follow from these assumptions, and also present a method for directly computing the marginal likelihood of a random sample with no missing observations. Also, we show how these assumptions lead to a general framework for characterizing parameter priors of multivariate distributions.

This note is meant to provide an introduction to linear models and the theories behind them. Our goal is to give a rigorous introduction to the readers with prior exposure to ordinary least squares. In machine learning, the output is usually a nonlinear function of the input. Deep learning even aims to find a nonlinear dependence with many layers which require a large amount of computation. However, most of these algorithms build upon simple linear models. We then describe linear models from different views and find the properties and theories behind the models. The linear model is the main technique in regression problems and the primary tool for it is the least squares approximation which minimizes a sum of squared errors. This is a natural choice when we're interested in finding the regression function which minimizes the corresponding expected squared error. We first describe ordinary least squares from three different points of view upon which we disturb the model with random noise and Gaussian noise. By Gaussian noise, the model gives rise to the likelihood so that we introduce a maximum likelihood estimator. It also develops some distribution theories for it via this Gaussian disturbance. The distribution theory of least squares will help us answer various questions and introduce related applications. We then prove least squares is the best unbiased linear model in the sense of mean squared error and most importantly, it actually approaches the theoretical limit. We end up with linear models with the Bayesian approach and beyond.

Neural networks (NNs) have shown high predictive performance, however, with shortcomings. Firstly, the reasons behind the classifications are not fully understood. Several explanation methods have been developed, but they do not provide mechanisms for users to interact with the explanations. Explanations are social, meaning they are a transfer of knowledge through interactions. Nonetheless, current explanation methods contribute only to one-way communication. Secondly, NNs tend to be overconfident, providing unreasonable uncertainty estimates on out-of-distribution observations. We overcome these difficulties by training a Bayesian convolutional neural network (CNN) that uses explanation feedback. After training, the model presents explanations of training sample classifications to an annotator. Based on the provided information, the annotator can accept or reject the explanations by providing feedback. Our proposed method utilizes this feedback for fine-tuning to correct the model such that the explanations and classifications improve. We use existing CNN architectures to demonstrate the method's effectiveness on one toy dataset (decoy MNIST) and two real-world datasets (Dogs vs. Cats and ISIC skin cancer). The experiments indicate that few annotated explanations and fine-tuning epochs are needed to improve the model and predictive performance, making the model more trustworthy and understandable.

Artificial neural networks will always make a prediction, even when completely uncertain and regardless of the consequences. This obliviousness of uncertainty is a major obstacle towards their adoption in practice. Techniques exist, however, to estimate the two major types of uncertainty: model uncertainty and observation noise in the data. Bayesian neural networks are theoretically well-founded models that can learn the model uncertainty of their predictions. Minor modifications to these models and their loss functions allow learning the observation noise for individual samples as well. This paper is the first to apply these techniques to predictive process monitoring. We found that they contribute towards more accurate predictions and work quickly. However, their main benefit resides with the uncertainty estimates themselves that allow the separation of higher-quality from lower-quality predictions and the building of confidence intervals. This leads to many interesting applications, enables an earlier adoption of prediction systems with smaller datasets and fosters a better cooperation with humans.

Mixed linear regression (MLR) model is among the most exemplary statistical tools for modeling non-linear distributions using a mixture of linear models. When the additive noise in MLR model is Gaussian, Expectation-Maximization (EM) algorithm is a widely-used algorithm for maximum likelihood estimation of MLR parameters. However, when noise is non-Gaussian, the steps of EM algorithm may not have closed-form update rules, which makes EM algorithm impractical. In this work, we study the maximum likelihood estimation of the parameters of MLR model when the additive noise has non-Gaussian distribution. In particular, we consider the case that noise has Laplacian distribution and we first show that unlike the the Gaussian case, the resulting sub-problems of EM algorithm in this case does not have closed-form update rule, thus preventing us from using EM in this case. To overcome this issue, we propose a new algorithm based on combining the alternating direction method of multipliers (ADMM) with EM algorithm idea. Our numerical experiments show that our method outperforms the EM algorithm in statistical accuracy and computational time in non-Gaussian noise case.

A primary motivation for the development and implementation of structural health monitoring systems, is the prospect of gaining the ability to make informed decisions regarding the operation and maintenance of structures and infrastructure. Unfortunately, descriptive labels for measured data corresponding to health-state information for the structure of interest are seldom available prior to the implementation of a monitoring system. This issue limits the applicability of the traditional supervised and unsupervised approaches to machine learning in the development of statistical classifiers for decision-supporting SHM systems. The current paper presents a risk-based formulation of active learning, in which the querying of class-label information is guided by the expected value of said information for each incipient data point. When applied to structural health monitoring, the querying of class labels can be mapped onto the inspection of a structure of interest in order to determine its health state. In the current paper, the risk-based active learning process is explained and visualised via a representative numerical example and subsequently applied to the Z24 Bridge benchmark. The results of the case studies indicate that a decision-maker's performance can be improved via the risk-based active learning of a statistical classifier, such that the decision process itself is taken into account.