Deep learning has revolutionized medical imaging, but its effectiveness is severely limited by insufficient labeled training data. This paper introduces a novel GAN-based semi-supervised learning framework specifically designed for low labeled-data regimes, evaluated across settings with 5 to 50 labeled samples per class. Our approach integrates three specialized neural networks -- a generator for class-conditioned image translation, a discriminator for authenticity assessment and classification, and a dedicated classifier -- within a three-phase training framework. The method alternates between supervised training on limited labeled data and unsupervised learning that leverages abundant unlabeled images through image-to-image translation rather than generation from noise. We employ ensemble-based pseudo-labeling that combines confidence-weighted predictions from the discriminator and classifier with temporal consistency through exponential moving averaging, enabling reliable label estimation for unlabeled data. Comprehensive evaluation across eleven MedMNIST datasets demonstrates that our approach achieves statistically significant improvements over six state-of-the-art GAN-based semi-supervised methods, with particularly strong performance in the extreme 5-shot setting where the scarcity of labeled data is most challenging. The framework maintains its superiority across all evaluated settings (5, 10, 20, and 50 shots per class). Our approach offers a practical solution for medical imaging applications where annotation costs are prohibitive, enabling robust classification performance even with minimal labeled data. Code is available at https://github.com/GuidoManni/SPARSE.

Fine-tuning lets practitioners repurpose aligned large language models (LLMs) for new domains, yet recent work reveals emergent misalignment (EMA): Even a small, domain-specific fine-tune can induce harmful behaviors far outside the target domain. Even in the case where model weights are hidden behind a fine-tuning API, this gives attackers inadvertent access to a broadly misaligned model in a way that can be hard to detect from the fine-tuning data alone. We present the first systematic study of in-training safeguards against EMA that are practical for providers who expose fine-tuning via an API. We investigate four training regularization interventions: (i) KL-divergence regularization toward a safe reference model, (ii) $\ell_2$ distance in feature space, (iii) projecting onto a safe subspace (SafeLoRA), and (iv) interleaving of a small amount of safe training examples from a general instruct-tuning dataset. We first evaluate the methods' emergent misalignment effect across four malicious, EMA-inducing tasks. Second, we assess the methods' impacts on benign tasks. We conclude with a discussion of open questions in emergent misalignment research.

Vision-Language Models (VLMs) have demonstrated remarkable generalization capabilities across a wide range of tasks. However, their performance often remains suboptimal when directly applied to specific downstream scenarios without task-specific adaptation. To enhance their utility while preserving data efficiency, recent research has increasingly focused on unsupervised adaptation methods that do not rely on labeled data. Despite the growing interest in this area, there remains a lack of a unified, task-oriented survey dedicated to unsupervised VLM adaptation. To bridge this gap, we present a comprehensive and structured overview of the field. We propose a taxonomy based on the availability and nature of unlabeled visual data, categorizing existing approaches into four key paradigms: Data-Free Transfer (no data), Unsupervised Domain Transfer (abundant data), Episodic Test-Time Adaptation (batch data), and Online Test-Time Adaptation (streaming data). Within this framework, we analyze core methodologies and adaptation strategies associated with each paradigm, aiming to establish a systematic understanding of the field. Additionally, we review representative benchmarks across diverse applications and highlight open challenges and promising directions for future research. An actively maintained repository of relevant literature is available at https://github.com/tim-learn/Awesome-LabelFree-VLMs.

Functional object arrangement (FORM) is the task of arranging objects to fulfill a function, e.g., "set up a dining table for two". One key challenge here is that the instructions for FORM are often under-specified and do not explicitly specify the desired object goal poses. This paper presents SetItUp, a neuro-symbolic framework that learns to specify the goal poses of objects from a few training examples and a structured natural-language task specification. SetItUp uses a grounding graph, which is composed of abstract spatial relations among objects (e.g., left-of), as its intermediate representation. This decomposes the FORM problem into two stages: (i) predicting this graph among objects and (ii) predicting object poses given the grounding graph. For (i), SetItUp leverages large language models (LLMs) to induce Python programs from a task specification and a few training examples. This program can be executed to generate grounding graphs in novel scenarios. For (ii), SetItUp pre-trains a collection of diffusion models to capture primitive spatial relations and online composes these models to predict object poses based on the grounding graph. We evaluated SetItUp on a dataset spanning three distinct task families: arranging tableware on a dining table, organizing items on a bookshelf, and laying out furniture in a bedroom. Experiments show that SetItUp outperforms existing models in generating functional, physically feasible, and aesthetically pleasing object arrangements. This article extends our conference paper published at Robotics: Science and Systems (RSS) 2024.

Identifying the seizure onset zone (SOZ) in patients with focal epilepsy is essential for surgical treatment and remains challenging due to its dependence on visual judgment by clinical experts. The development of machine learning can assist in diagnosis and has made promising progress. However, unlike data in other fields, medical data is usually collected from individual patients, and each patient has different illnesses, physical conditions, and medical histories, which leads to differences in the distribution of each patient's data. This makes it difficult for a machine learning model to achieve consistently reliable performance in every new patient dataset, which we refer to as the "cross-patient problem." In this paper, we propose a method to fine-tune a pretrained model using patient-specific weights for every new test patient to improve diagnostic performance. First, the supervised learning method is used to train a machine learning model. Next, using the intermediate features of the trained model obtained through the test patient data, the similarity between the test patient data and each training patient's data is defined to determine the weight of each training patient to be used in the following fine-tuning. Finally, we fine-tune all parameters in the pretrained model with training data and patient weights. In the experiment, the leave-one-patient-out method is used to evaluate the proposed method, and the results show improved classification accuracy for every test patient, with an average improvement of more than 10%.

Neural Combinatorial Optimization aims to learn to solve a class of combinatorial problems through data-driven methods and notably through employing neural networks by learning the underlying distribution of problem instances. While, so far neural methods struggle to outperform highly engineered problem specific meta-heuristics, this work explores a novel approach to formulate the distribution of problem instances to learn from and, more importantly, plant a structure in the sampled problem instances. In application to routing problems, we generate large problem instances that represent custom base problem instance distributions from which training instances are sampled. The test instances to evaluate the methods on the routing task consist of unseen problems sampled from the underlying large problem instance. We evaluate representative NCO methods and specialized Operation Research meta heuristics on this novel task and demonstrate that the performance gap between neural routing solvers and highly specialized meta-heuristics decreases when learning from sub-samples drawn from a fixed base node distribution.

This paper develops a hybrid quantum approach for graph-based semi-supervised learning to enhance performance in scenarios where labeled data is scarce. We introduce two enhanced quantum models, the Improved Laplacian Quantum Semi-Supervised Learning (ILQSSL) and the Improved Poisson Quantum Semi-Supervised Learning (IPQSSL), that incorporate advanced label propagation strategies within variational quantum circuits. These models utilize QR decomposition to embed graph structure directly into quantum states, thereby enabling more effective learning in low-label settings. We validate our methods across four benchmark datasets like Iris, Wine, Heart Disease, and German Credit Card -- and show that both ILQSSL and IPQSSL consistently outperform leading classical semi-supervised learning algorithms, particularly under limited supervision. Beyond standard performance metrics, we examine the effect of circuit depth and qubit count on learning quality by analyzing entanglement entropy and Randomized Benchmarking (RB). Our results suggest that while some level of entanglement improves the model's ability to generalize, increased circuit complexity may introduce noise that undermines performance on current quantum hardware. Overall, the study highlights the potential of quantum-enhanced models for semi-supervised learning, offering practical insights into how quantum circuits can be designed to balance expressivity and stability. These findings support the role of quantum machine learning in advancing data-efficient classification, especially in applications constrained by label availability and hardware limitations.

Even though Active Learning (AL) is widely studied, it is rarely applied in contexts outside its own scientific literature. We posit that the reason for this is AL's high computational cost coupled with the comparatively small lifts it is typically able to generate in scenarios with few labeled points. In this work we study the impact of different methods to combat this low data scenario, namely data augmentation (DA), semi-supervised learning (SSL) and AL. We find that AL is by far the least efficient method of solving the low data problem, generating a lift of only 1-4\% over random sampling, while DA and SSL methods can generate up to 60\% lift in combination with random sampling. However, when AL is combined with strong DA and SSL techniques, it surprisingly is still able to provide improvements. Based on these results, we frame AL not as a method to combat missing labels, but as the final building block to squeeze the last bits of performance out of data after appropriate DA and SSL methods as been applied.

Understanding and modeling buyer intent is a foundational challenge in optimizing search query reformulation within the dynamic landscape of e-commerce search systems. This work introduces a robust data pipeline designed to mine and analyze large-scale buyer query logs, with a focus on extracting fine-grained intent signals from both explicit interactions and implicit behavioral cues. Leveraging advanced sequence mining techniques and supervised learning models, the pipeline systematically captures patterns indicative of latent purchase intent, enabling the construction of a high-fidelity, intent-rich dataset. The proposed framework facilitates the development of adaptive query rewrite strategies by grounding reformulations in inferred user intent rather than surface-level lexical signals. This alignment between query rewriting and underlying user objectives enhances both retrieval relevance and downstream engagement metrics. Empirical evaluations across multiple product verticals demonstrate measurable gains in precision-oriented relevance metrics, underscoring the efficacy of intent-aware reformulation. Our findings highlight the value of intent-centric modeling in bridging the gap between sparse user inputs and complex product discovery goals, and establish a scalable foundation for future research in user-aligned neural retrieval and ranking systems.

Self-supervised learning methods like masked autoen-coders (MAE) have shown significant promise in learning robust feature representations, particularly in image reconstruction-based pretraining task. However, their performance is often strongly dependent on the masking strategies used during training and can degrade when applied to out-of-distribution data. T o address these limitations, we introduce the masked implicit neural representations (MINR) framework that synergizes implicit neural representations with masked image modeling. MINR learns a continuous function to represent images, enabling more robust and gen-eralizable reconstructions irrespective of masking strategies. Our experiments demonstrate that MINR not only outperforms MAE in in-domain scenarios but also in out-of-distribution settings, while reducing model complexity. The versatility of MINR extends to various self-supervised learning applications, confirming its utility as a robust and efficient alternative to existing frameworks.