Conference by Yann LeCun, computer scientist working in machine learning, computer vision, mobile robotics and computational neuroscience, who sees self-supervised learning as a potential solution for problems in reinforcement learning, as it has the advantage of taking both input and output as part of a complete system, making it effective for example in image completing, image transferring, time sequence data prediction, etc. While the model's complexity increases with the addition of feedback information, self-supervised learning models significantly reduce human involvement in the process.

We propose a novel approach for learning node representations in directed graphs, which maintains separate views or embedding spaces for the two distinct node roles induced by the directionality of the edges. In order to achieve this, we propose a novel alternating random walk strategy to generate training samples from the directed graph while preserving the role information. These samples are then trained using Skip-Gram with Negative Sampling (SGNS) with nodes retaining their source/target semantics. We conduct extensive experimental evaluation to showcase our effectiveness on several real-world datasets on link prediction, multi-label classification and graph reconstruction tasks. We show that the embeddings from our approach are indeed robust, generalizable and well performing across multiple kinds of tasks and networks. We show that we consistently outperform all random-walk based neural embedding methods for link prediction and graph reconstruction tasks. In addition to providing a theoretical interpretation of our method we also show that we are more considerably robust than the other directed graph approaches.

Synthetic lethality (SL) is a promising concept for novel discovery of anti-cancer drug targets. However, wet-lab experiments for detecting SLs are faced with various challenges, such as high cost, low consistency across platforms or cell lines. Therefore, computational prediction methods are needed to address these issues. This paper proposes a novel SL prediction method, named SL2MF, which employs logistic matrix factorization to learn latent representations of genes from the observed SL data. The probability that two genes are likely to form SL is modeled by the linear combination of gene latent vectors. As known SL pairs are more trustworthy than unknown pairs, we design importance weighting schemes to assign higher importance weights for known SL pairs and lower importance weights for unknown pairs in SL2MF. Moreover, we also incorporate biological knowledge about genes from protein-protein interaction (PPI) data and Gene Ontology (GO). In particular, we calculate the similarity between genes based on their GO annotations and topological properties in the PPI network. Extensive experiments on the SL interaction data from SynLethDB database have been conducted to demonstrate the effectiveness of SL2MF.

Supervised learning – A blessing we have in this machines era. It helps to depict inputs to outputs. It uses labelled training data to deduce a function which has set of training examples. The majority of practical machine learning uses supervised learning as on date. AILabPage defines Machine Learning as "A focal point where business, data and experience meets emerging technology and decides to work together".

Good parameter settings are crucial to achieve high performance in many areas of artificial intelligence (AI), such as propositional satisfiability solving, AI planning, scheduling, and machine learning (in particular deep learning). Automated algorithm configuration methods have recently received much attention in the AI community since they replace tedious, irreproducible and error-prone manual parameter tuning and can lead to new state-of-the-art performance. However, practical applications of algorithm configuration are prone to several (often subtle) pitfalls in the experimental design that can render the procedure ineffective. We identify several common issues and propose best practices for avoiding them. As one possibility for automatically handling as many of these as possible, we also propose a tool called GenericWrapper4AC.

ROC curves are widely used because they are relatively simple to understand and capture more than one aspect of the classification.

Meta-learning, or learning to learn, is the science of systematically observing how different machine learning approaches perform on a wide range of learning tasks, and then learning from this experience, or meta-data, to learn new tasks much faster than otherwise possible. Not only does this dramatically speed up and improve the design of machine learning pipelines or neural architectures, it also allows us to replace hand-engineered algorithms with novel approaches learned in a data-driven way. In this chapter, we provide an overview of the state of the art in this fascinating and continuously evolving field.

In conventional binary classification, examples are labeled as either positive (P) or negative (N), and we train a classifier on these labeled examples. On the contrary, positive-unlabeled (PU) learning addresses the problem of learning a classifier from P and unlabeled (U) data, without need of explicitly identifying N data (Elkan & Noto, 2008; Ward et al., 2009). PU learning finds its usefulness in many real-world problems. For example, in one-class remote sensing classification (Li et al., 2011), we seek to extract a specific land-cover class from an image. While it is easy to label examples of this specific land-cover class of interest, examples not belonging to this class are too diverse to be exhaustively annotated. The same problem arises in text classification, as it is difficult or even impossible to compile a set of N samples that provides a comprehensive characterization of everything that is not in the P class (Liu et al., 2003; Fung et al., 2006). Besides, PU learning has also been applied to other domains such as outlier detection (Hido et al., 2008; Scott & Blanchard, 2009), medical diagnosis (Zuluaga et al., 2011), or time series classification (Nguyen et al., 2011). By carefully examining the above examples, we find out that the most difficult step is often to collect a fully representative N set, whereas only labeling a small portion of all possible N data is relatively easy. Therefore, in this paper, we propose to study the problem of learning from P, U and biased N (bN) data, which we name PUbN learning hereinafter.

Computing universal distributed representations of sentences is a fundamental task in natural language processing. We propose a simple, yet surprisingly powerful unsupervised method to learn such representations by enforcing consistency constraints on sequences of tokens. We consider two classes of such constraints - sequences that form a sentence and between two sequences that form a sentence when merged. We learn a sentence encoder by training it to distinguish between consistent and inconsistent examples. Extensive evaluation on several transfer learning and linguistic probing tasks shows improved performance over strong unsupervised and supervised baselines, substantially surpassing them in several cases. In natural language processing, the use of distributed representations has become standard through the effective use of word embeddings.

Deep reinforcement learning (RL) algorithms have shown an impressive ability to learn complex control policies in high-dimensional environments. However, despite the ever-increasing performance on popular benchmarks like the Arcade Learning Environment (ALE), policies learned by deep RL algorithms can struggle to generalize when evaluated in remarkably similar environments. These results are unexpected given the fact that, in supervised learning, deep neural networks often learn robust features that generalize across tasks. In this paper, we study the generalization capabilities of DQN in order to aid in understanding this mismatch between generalization in deep RL and supervised learning methods. We provide evidence suggesting that DQN overspecializes to the domain it is trained on. We then comprehensively evaluate the impact of traditional methods of regularization from supervised learning, $\ell_2$ and dropout, and of reusing learned representations to improve the generalization capabilities of DQN. We perform this study using different game modes of Atari 2600 games, a recently introduced modification for the ALE which supports slight variations of the Atari 2600 games used for benchmarking in the field. Despite regularization being largely underutilized in deep RL, we show that it can, in fact, help DQN learn more general features. These features can then be reused and fine-tuned on similar tasks, considerably improving the sample efficiency of DQN.