Designing effective black-box optimizers is hampered by limited problem-specific knowledge and manual control that spans months for almost every detail. In this paper, we present \textit{DesignX}, the first automated algorithm design framework that generates an effective optimizer specific to a given black-box optimization problem within seconds. Rooted in the first principles, we identify two key sub-tasks: 1) algorithm structure generation and 2) hyperparameter control. To enable systematic construction, a comprehensive modular algorithmic space is first built, embracing hundreds of algorithm components collected from decades of research. We then introduce a dual-agent reinforcement learning system that collaborates on structural and parametric design through a novel cooperative training objective, enabling large-scale meta-training across 10k diverse instances. Remarkably, through days of autonomous learning, the DesignX-generated optimizers continuously surpass human-crafted optimizers by orders of magnitude, either on synthetic testbed or on realistic optimization scenarios such as Protein-docking, AutoML and UAV path planning. Further in-depth analysis reveals DesignX's capability to discover non-trivial algorithm patterns beyond expert intuition, which, conversely, provides valuable design insights for the optimization community. We provide DesignX's Python project at~ https://github.com/MetaEvo/DesignX.

Breast cancer is considered the most critical and frequently diagnosed cancer in women worldwide, leading to an increase in cancer-related mortality. Early and accurate detection is crucial as it can help mitigate possible threats while improving survival rates. In terms of prediction, conventional diagnostic methods are often limited by variability, cost, and, most importantly, risk of misdiagnosis. To address these challenges, machine learning (ML) has emerged as a powerful tool for computer-aided diagnosis, with feature selection playing a vital role in improving model performance and interpretability. This research study proposes an integrated framework that incorporates customized Particle Swarm Optimization (PSO) for feature selection. This framework has been evaluated on a comprehensive set of 29 different models, spanning classical classifiers, ensemble techniques, neural networks, probabilistic algorithms, and instance-based algorithms. To ensure interpretability and clinical relevance, the study uses cross-validation in conjunction with explainable AI methods. Experimental evaluation showed that the proposed approach achieved a superior score of 99.1\% across all performance metrics, including accuracy and precision, while effectively reducing dimensionality and providing transparent, model-agnostic explanations. The results highlight the potential of combining swarm intelligence with explainable ML for robust, trustworthy, and clinically meaningful breast cancer diagnosis.

We demonstrate the efficacy of symbolic regression (SR) to probe models of particle physics Beyond the Standard Model (BSM), by considering the so-called Constrained Minimal Supersymmetric Standard Model (CMSSM). Like many incarnations of BSM physics this model has a number (four) of arbitrary parameters, which determine the experimental signals, and cosmological observables such as the dark matter relic density. We show that analysis of the phenomenology can be greatly accelerated by using symbolic expressions derived for the observables in terms of the input parameters. Here we focus on the Higgs mass, the cold dark matter relic density, and the contribution to the anomalous magnetic moment of the muon. We find that SR can produce remarkably accurate expressions. Using them we make global fits to derive the posterior probability densities of the CMSSM input parameters which are in good agreement with those performed using conventional methods. Moreover, we demonstrate a major advantage of SR which is the ability to make fits using differentiable methods rather than sampling methods. We also compare the method with neural network (NN) regression. SR produces more globally robust results, while NNs require data that is focussed on the promising regions in order to be equally performant.

In recent years, large language models (LLMs) have made remarkable progress, with model optimization primarily relying on gradient-based optimizers such as Adam. However, these gradient-based methods impose stringent hardware requirements, demanding high-concurrency, high-memory GPUs. Moreover, they require all neural network operations to be differentiable, thereby excluding many promising non-differentiable architectures from practical use. To address these limitations, we propose EA4LLM, an evolutionary algorithm for optimizing LLMs, and, for the first time, empirically verify full-parameter optimization from the pretraining stage across model sizes ranging from 0.5B to 32B. We conduct extensive experiments and provide key insights into how evolutionary algorithms can effectively optimize neural networks. Our work challenges the prevailing assumption that gradient-based optimization is the only viable approach for training neural networks. It also holds significant potential to reduce the computational cost of training large language models, thereby enabling groups with limited computational resources to participate in deep learning research.

Active particles are entities that sustain persistent out-of-equilibrium motion by consuming energy. Under certain conditions, they exhibit the tendency to self-organize through coordinated movements, such as swarming via aggregation. While performing non-cooperative foraging tasks, the emergence of such swarming behavior in foragers, exemplifying active particles, has been attributed to the partial observability of the environment, in which the presence of another forager can serve as a proxy signal to indicate the potential presence of a food source or a resource patch. In this paper, we validate this phenomenon by simulating multiple self-propelled foragers as they forage from multiple resource patches in a non-cooperative manner. These foragers operate in a continuous two-dimensional space with stochastic position updates and partial observability. We evolve a shared policy in the form of a continuous-time recurrent neural network that serves as a velocity controller for the foragers. To this end, we use an evolutionary strategy algorithm wherein the different samples of the policy-distribution are evaluated in the same rollout. Then we show that agents are able to learn to adaptively forage in the environment. Next, we show the emergence of swarming in the form of aggregation among the foragers when resource patches are absent. We observe that the strength of this swarming behavior appears to be inversely proportional to the amount of resource stored in the foragers, which supports the risk-sensitive foraging claims. Empirical analysis of the learned controller's hidden states in minimal test runs uncovers their sensitivity to the amount of resource stored in a forager. Clamping these hidden states to represent a lesser amount of resource hastens its learned aggregation behavior.

Meta-Black-Box Optimization (MetaBBO) streamlines the automation of optimization algorithm design through meta-learning. It typically employs a bi-level structure: the meta-level policy undergoes meta-training to reduce the manual effort required in developing algorithms for low-level optimization tasks. The original MetaBox (2023) provided the first open-source framework for reinforcement learning-based single-objective MetaBBO. However, its relatively narrow scope no longer keep pace with the swift advancement in this field. In this paper, we introduce MetaBox-v2 (https://github.com/MetaEvo/MetaBox) as a milestone upgrade with four novel features: 1) a unified architecture supporting RL, evolutionary, and gradient-based approaches, by which we reproduce $23$ up-to-date baselines; 2) efficient parallelization schemes, which reduce the training/testing time by $10-40$x; 3) a comprehensive benchmark suite of $18$ synthetic/realistic tasks ($1900$+ instances) spanning single-objective, multi-objective, multi-model, and multi-task optimization scenarios; 4) plentiful and extensible interfaces for custom analysis/visualization and integrating to external optimization tools/benchmarks. To show the utility of MetaBox-v2, we carry out a systematic case study that evaluates the built-in baselines in terms of the optimization performance, generalization ability and learning efficiency. Valuable insights are concluded from thorough and detailed analysis for practitioners and those new to the field.

Feature selection is a combinatorial optimization problem that is NP -hard. Conventional approaches often employ heuristic or greedy strategies, which are prone to premature convergence and may fail to capture subtle yet informative features. This limitation becomes especially critical in high - dimensional datasets, where complex and interdependent feature relationships prevail. We introduce the HeFS (Helper - Enhanced Feature Selection) framework to refine feature subsets produced by existing algorithms. HeFS systematically searches the residual feature space to identify a Helper Set-- features that complement the original subset and improve classification performance. The approach employs a biased initialization scheme and a ratio-guided mutation mechanism within a genetic algorithm, coupled with Pareto - based multi - objective optimization to jointly maximize predictive accuracy and feature complementarity. Experiments on 18 benchmark datasets demonstrate that HeFS consistently identifies overlooked yet informative features and achieves superior performance over state-of-the - art methods, including in challenging domains such as gastric cancer classification, drug toxicity prediction, and computer science applications.

This is the first part of the comprehensive review, focusing on the historical development of Agent-Based Modeling (ABM) and its classic cases. It begins by discussing the development history and design principles of Agent-Based Modeling (ABM), helping readers understand the significant challenges that traditional physical simulation methods face in the social domain. Then, it provides a detailed introduction to foundational models for simulating social systems, including individual models, environmental models, and rule-based models. Finally, it presents classic cases of social simulation, covering three types: thought experiments, mechanism exploration, and parallel optimization.

Fixed degree-of-freedom (DoF) loading mechanisms often suffer from excessive actuators, complex control, and limited adaptability to dynamic tasks. This study proposes an innovative mechanism of underactuated metamorphic loading manipulators (UMLM), integrating a metamorphic arm with a passively adaptive gripper. The metamorphic arm exploits geometric constraints, enabling the topology reconfiguration and flexible motion trajectories without additional actuators. The adaptive gripper, driven entirely by the arm, conforms to diverse objects through passive compliance. A structural model is developed, and a kinetostatics analysis is conducted to investigate isomorphic grasping configurations. To optimize performance, Particle-Swarm Optimization (PSO) is utilized to refine the gripper's dimensional parameters, ensuring robust adaptability across various applications. Simulation results validate the UMLM's easily implemented control strategy, operational versatility, and effectiveness in grasping diverse objects in dynamic environments. This work underscores the practical potential of underactuated metamorphic mechanisms in applications requiring efficient and adaptable loading solutions. Beyond the specific design, this generalized modeling and optimization framework extends to a broader class of manipulators, offering a scalable approach to the development of robotic systems that require efficiency, flexibility, and robust performance.

Poultry farming faces increasing pressure to meet productivity targets while ensuring animal welfare and environmental compliance. Yet many small and medium-sized farms lack affordable, integrated tools for continuous monitoring and decision-making, relying instead on manual, reactive inspections. This paper presents Poultry Farm Intelligence (PoultryFI) - a modular, cost-effective platform that integrates six AI-powered modules: Camera Placement Optimizer, Audio-Visual Monitoring, Analytics & Alerting, Real-Time Egg Counting, Production & Profitability Forecasting, and a Recommendation Module. Camera layouts are first optimized offline using evolutionary algorithms for full poultry house coverage with minimal hardware. The Audio-Visual Monitoring module extracts welfare indicators from synchronized video, audio, and feeding data. Analytics & Alerting produces daily summaries and real-time notifications, while Real-Time Egg Counting uses an edge vision model to automate production tracking. Forecasting models predict egg yield and feed consumption up to 10 days in advance, and the Recommendation Module integrates forecasts with weather data to guide environmental and operational adjustments. This is among the first systems to combine low-cost sensing, edge analytics, and prescriptive AI to continuously monitor flocks, predict production, and optimize performance. Field trials demonstrate 100% egg-count accuracy on Raspberry Pi 5, robust anomaly detection, and reliable short-term forecasting. PoultryFI bridges the gap between isolated pilot tools and scalable, farm-wide intelligence, empowering producers to proactively safeguard welfare and profitability.