Accurate geometric modeling of the aortic valve from 3D CT images is essential for biomechanical analysis and patient-specific simulations to assess valve health or make a preoperative plan. However, it remains challenging to generate aortic valve meshes with both high-quality and consistency across different patients. Traditional approaches often produce triangular meshes with irregular topologies, which can result in poorly shaped elements and inconsistent correspondence due to inter-patient anatomical variation. In this work, we address these challenges by introducing a template-fitting pipeline with deep neural networks to generate structured quad (i.e., quadrilateral) meshes from 3D CT images to represent aortic valve geometries. By remeshing aortic valves of all patients with a common quad mesh template, we ensure a uniform mesh topology with consistent node-to-node and element-to-element correspondence across patients. This consistency enables us to simplify the learning objective of the deep neural networks, by employing a loss function with only two terms (i.e., a geometry reconstruction term and a smoothness regularization term), which is sufficient to preserve mesh smoothness and element quality. Our experiments demonstrate that the proposed approach produces high-quality aortic valve surface meshes with improved smoothness and shape quality, while requiring fewer explicit regularization terms compared to the traditional methods. These results highlight that using structured quad meshes for the template and neural network training not only ensures mesh correspondence and quality but also simplifies the training process, thus enhancing the effectiveness and efficiency of aortic valve modeling.

Imitation learning-based robot control policies are enjoying renewed interest in video-based robotics. However, it remains unclear whether this approach applies to X-ray-guided procedures, such as spine instrumentation. This is because interpretation of multi-view X-rays is complex. We examine opportunities and challenges for imitation policy learning in bi-plane-guided cannula insertion. We develop an in silico sandbox for scalable, automated simulation of X-ray-guided spine procedures with a high degree of realism. We curate a dataset of correct trajectories and corresponding bi-planar X-ray sequences that emulate the stepwise alignment of providers. We then train imitation learning policies for planning and open-loop control that iteratively align a cannula solely based on visual information. This precisely controlled setup offers insights into limitations and capabilities of this method. Our policy succeeded on the first attempt in 68.5% of cases, maintaining safe intra-pedicular trajectories across diverse vertebral levels. The policy generalized to complex anatomy, including fractures, and remained robust to varied initializations. Rollouts on real bi-planar X-rays further suggest that the model can produce plausible trajectories, despite training exclusively in simulation. While these preliminary results are promising, we also identify limitations, especially in entry point precision. Full closed-look control will require additional considerations around how to provide sufficiently frequent feedback. With more robust priors and domain knowledge, such models may provide a foundation for future efforts toward lightweight and CT-free robotic intra-operative spinal navigation.

As low-resourced languages are increasingly incorporated into NLP research, there is an emphasis on collecting large-scale datasets. But in prioritizing quantity over quality, we risk 1) building language technologies that perform poorly for these languages and 2) producing harmful content that perpetuates societal biases. In this paper, we investigate the quality of Machine Translation (MT) datasets for three low-resourced languages--Afan Oromo, Amharic, and Tigrinya, with a focus on the gender representation in the datasets. Our findings demonstrate that while training data has a large representation of political and religious domain text, benchmark datasets are focused on news, health, and sports. We also found a large skew towards the male gender--in names of persons, the grammatical gender of verbs, and in stereotypical depictions in the datasets. Further, we found harmful and toxic depictions against women, which were more prominent for the language with the largest amount of data, underscoring that quantity does not guarantee quality. We hope that our work inspires further inquiry into the datasets collected for low-resourced languages and prompts early mitigation of harmful content. WARNING: This paper contains discussion of NSFW content that some may find disturbing.

Social and collaborative platforms emit multivariate time-series traces in which early interactions--such as views, likes, or downloads--are followed, sometimes months or years later, by higher impact like citations, sales, or reviews. We formalize this setting as Lead-Lag Forecasting (LLF): given an early usage channel (the lead), predict a correlated but temporally shifted outcome channel (the lag). Despite the ubiquity of such patterns, LLF has not been treated as a unified forecasting problem within the time-series community, largely due to the absence of standardized datasets. To anchor research in LLF, here we present two high-volume benchmark datasets--arXiv (accesses citations of 2.3M papers) and GitHub (pushes/stars forks of 3M repositories)--and outline additional domains with analogous lead-lag dynamics, including Wikipedia (page-views edits), Spotify (streams concert attendance), e-commerce (click-throughs purchases), and LinkedIn profile (views messages). Our datasets provide ideal testbeds for lead-lag forecasting, by capturing long-horizon dynamics across years, spanning the full spectrum of outcomes, and avoiding sur-vivorship bias in sampling. We documented all technical details of data cura-tion and cleaning, verified the presence of lead-lag dynamics through statistical and classification tests, and benchmarked parametric and non-parametric baselines for regression. Our study establishes LLF as a novel forecasting paradigm and lays an empirical foundation for its systematic exploration in social and usage data. The success of human activities is often measured by their collective impact, ranging from music streams and movie box office revenues to product sales and social media popularity. These impact metrics typically follow heavy-tailed distributions (Clauset et al., 2009) and slow decay patterns across timescales (Candia et al., 2019), making early identification of future hits fundamentally challenging (Cheng et al., 2014; Martin et al., 2016). At the same time, digital platforms increasingly log online user interactions--searches, views, downloads, likes, and shares--that often precede these long-term dynamics. These temporal lead-lag dynamics are remarkably ubiquitous, spanning domains as diverse as science (Haque & Ginsparg, 2009), economics (Wu & Brynjolfsson, 2015), arts (Goel et al., 2010), culture (Gruhl et al., 2005), and social movements (Johnson et al., 2016). A systematic understanding of such lead-lag dynamics is not only crucial for anticipating and optimizing impact in digital ecosystems, but also essential for designing effective strategies that identify and promote emerging innovations and products.

This paper examines how decision makers in academia, government, business, and civil society navigate questions of power in implementations of artificial intelligence (AI). The study explores how individuals experience and exercise "levers of power," which are presented as social mechanisms that shape institutional responses to technological change. The study reports on the responses of personalized questionnaires designed to gather insight on a decision maker's institutional purview, based on an institutional governance framework developed from the work of Neo Institutionalists. Findings present the anonymized, real responses and circumstances of respondents in the form of twelve fictional personas of high-level decision makers from North America and Europe. These personas illustrate how personal agency, organizational logics, and institutional infrastructures may intersect in the governance of AI. The decision makers' responses to the questionnaires then inform a discussion of the field level personal power of decision-makers, methods of fostering institutional stability in times of change, and methods of influencing institutional change in the field of AI. The final section of the discussion presents a table of the dynamics of the levers of power in the field of AI for change makers and 5 testable hypotheses for institutional and social movement researchers. In summary, this study provides insight on the means for policymakers within institutions and their counterparts in civil society to personally engage with AI governance.

Deep learned (DL) models for image recognition have been shown to fail to generalize to data from different devices, populations, etc. COVID-19 detection from Chest X-rays (CXRs), in particular, has been shown to fail to generalize to out-of-distribution (OOD) data from new clinical sources not covered in the training set. This occurs because models learn to exploit shortcuts - source-specific artifacts that do not translate to new distributions - rather than reasonable biomarkers to maximize performance on in-distribution (ID) data. Rendering the models more robust to distribution shifts, our study investigates the use of fundamental noise injection techniques (Gaussian, Speckle, Poisson, and Salt and Pepper) during training. Our empirical results demonstrate that this technique can significantly reduce the performance gap between ID and OOD evaluation from 0.10 0.20 to 0.01 0.06, based on results averaged over ten random seeds across key metrics such as AUC, F1, accuracy, recall and specificity.

Multimodal Large Language Models (MLLMs) are reshaping how modern agentic systems reason over sequential user-behavior data. However, whether textual or image representations of user behavior data are more effective for maximizing MLLM performance remains underexplored. We present \texttt{BehaviorLens}, a systematic benchmarking framework for assessing modality trade-offs in user-behavior reasoning across six MLLMs by representing transaction data as (1) a text paragraph, (2) a scatter plot, and (3) a flowchart. Using a real-world purchase-sequence dataset, we find that when data is represented as images, MLLMs next-purchase prediction accuracy is improved by 87.5% compared with an equivalent textual representation without any additional computational cost.

Optimizing large-language model (LLM) training on distributed domain-specific accelerator systems presents significant challenges due to its complex optimization space. Existing optimization methods, however, rely on time-consuming manual tuning or resource-intensive black-box searches, which struggle to keep pace with the rapidly evolving LLM domain, leading to slow development and underutilized resources. To address this, we introduce ASAP, an Agentic Solution to Auto-optimize Performance of Large-Scale LLM Training. It is a multi-agent system, featuring Coordinator, Analyzer, and Proposal agents, which integrates LLM reasoning with insights from performance profiling tools, roofline analysis, and a knowledge base of best practices and successful past optimizations from human experts. Our proposed design can automate the diagnosis of performance bottlenecks and recommend optimized sharding configurations with reasoning, thus effectively improving the efficiency of distributed LLM training. Experiments have shown that the ASAP-generated sharding configurations can contribute up to 28% training step time reduction and 1.43 times throughput improvement. When combined with additional optimization from human experts, throughput can be further increased to 2.58 times. The proposed ASAP promises to provide a scalable and explainable methodology for AI-assisted performance engineering in large-scale LLM training.

Deep Q-Networks (DQNs) estimate future returns by learning from transitions sampled from a replay buffer. However, the target updates in DQN often rely on next states generated by actions from past, potentially suboptimal, policy. As a result, these states may not provide informative learning signals, causing high variance into the update process. This issue is exacerbated when the sampled transitions are poorly aligned with the agent's current policy. To address this limitation, we propose the Successor-state Aggregation Deep Q-Network (SADQ), which explicitly models environment dynamics using a stochastic transition model. SADQ integrates successor-state distributions into the Q-value estimation process, enabling more stable and policy-aligned value updates. Additionally, it explores a more efficient action selection strategy with the modeled transition structure. We provide theoretical guarantees that SADQ maintains unbiased value estimates while reducing training variance. Our extensive empirical results across standard RL benchmarks and real-world vector-based control tasks demonstrate that SADQ consistently outperforms DQN variants in both stability and learning efficiency.

Medical image labels are often organized by taxonomies (e.g., organ - tissue - subtype), yet standard self-supervised learning (SSL) ignores this structure. We present a hierarchy-preserving contrastive framework that makes the label tree a first-class training signal and an evaluation target. Our approach introduces two plug-in objectives: Hierarchy-Weighted Contrastive (HWC), which scales positive/negative pair strengths by shared ancestors to promote within-parent coherence, and Level-Aware Margin (LAM), a prototype margin that separates ancestor groups across levels. The formulation is geometry-agnostic and applies to Euclidean and hyperbolic embeddings without architectural changes. Across several benchmarks, including breast histopathology, the proposed objectives consistently improve representation quality over strong SSL baselines while better respecting the taxonomy. We evaluate with metrics tailored to hierarchy faithfulness: HF1 (hierarchical F1), H-Acc (tree-distance-weighted accuracy), and parent-distance violation rate. We also report top-1 accuracy for completeness. Ablations show that HWC and LAM are effective even without curvature, and combining them yields the most taxonomy-aligned representations. Taken together, these results provide a simple, general recipe for learning medical image representations that respect the label tree and advance both performance and interpretability in hierarchy-rich domains.