Industry
Case study of a differentiable heterogeneous multiphysics solver for a nuclear fusion application
Coughlin, Jack B., Joglekar, Archis, Brodrick, Jonathan, Lavin, Alexander
This work presents a case study of a heterogeneous multiphysics solver from the nuclear fusion domain. At the macroscopic scale, an auto-differentiable ODE solver in JAX computes the evolution of the pulsed power circuit and bulk plasma parameters for a compressing Z Pinch. The ODE solver requires a closure for the impedance of the plasma load obtained via root-finding at every timestep, which we solve efficiently using gradient-based Newton iteration. However, incorporating non-differentiable production-grade plasma solvers like Gkeyll (a C/CUDA plasma simulation suite) into a gradient-based workflow is non-trivial. The ''Tesseract'' software addresses this challenge by providing a multi-physics differentiable abstraction layer made fully compatible with JAX (through the `tesseract_jax` adapter). This architecture ensures end-to-end differentiability while allowing seamless interchange between high-fidelity solvers (Gkeyll), neural surrogates, and analytical approximations for rapid, progressive prototyping.
GeoX-Bench: Benchmarking Cross-View Geo-Localization and Pose Estimation Capabilities of Large Multimodal Models
Zheng, Yushuo, Ying, Jiangyong, Duan, Huiyu, Li, Chunyi, Zhang, Zicheng, Liu, Jing, Liu, Xiaohong, Zhai, Guangtao
Large multimodal models (LMMs) have demonstrated remarkable capabilities across a wide range of tasks, however their knowledge and abilities in the cross-view geo-localization and pose estimation domains remain unexplored, despite potential benefits for navigation, autonomous driving, outdoor robotics, \textit{etc}. To bridge this gap, we introduce \textbf{GeoX-Bench}, a comprehensive \underline{Bench}mark designed to explore and evaluate the capabilities of LMMs in \underline{cross}-view \underline{Geo}-localization and pose estimation. Specifically, GeoX-Bench contains 10,859 panoramic-satellite image pairs spanning 128 cities in 49 countries, along with corresponding 755,976 question-answering (QA) pairs. Among these, 42,900 QA pairs are designated for benchmarking, while the remaining are intended to enhance the capabilities of LMMs. Based on GeoX-Bench, we evaluate the capabilities of 25 state-of-the-art LMMs on cross-view geo-localization and pose estimation tasks, and further explore the empowered capabilities of instruction-tuning. Our benchmark demonstrate that while current LMMs achieve impressive performance in geo-localization tasks, their effectiveness declines significantly on the more complex pose estimation tasks, highlighting a critical area for future improvement, and instruction-tuning LMMs on the training data of GeoX-Bench can significantly improve the cross-view geo-sense abilities. The GeoX-Bench is available at \textcolor{magenta}{https://github.com/IntMeGroup/GeoX-Bench}.
Seek and You Shall Fold
Sellam, Nadav Bojan, Bojan, Meital, Schanda, Paul, Bronstein, Alex
Accurate protein structures are essential for understanding biological function, yet incorporating experimental data into protein generative models remains a major challenge. Most predictors of experimental observables are non-differentiable, making them incompatible with gradient-based conditional sampling. This is especially limiting in nuclear magnetic resonance, where rich data such as chemical shifts are hard to directly integrate into generative modeling. We introduce a framework for non-differentiable guidance of protein generative models, coupling a continuous diffusion-based generator with any black-box objective via a tailored genetic algorithm. We demonstrate its effectiveness across three modalities: pairwise distance constraints, nuclear Overhauser effect restraints, and for the first time chemical shifts. These results establish chemical shift guided structure generation as feasible, expose key weaknesses in current predictors, and showcase a general strategy for incorporating diverse experimental signals. Our work points toward automated, data-conditioned protein modeling beyond the limits of differentiability.
LLM-based Multi-Agent System for Simulating Strategic and Goal-Oriented Data Marketplaces
Sashihara, Jun, Fujita, Yukihisa, Nakamura, Kota, Kuwahara, Masahiro, Hayashi, Teruaki
Abstract--Data marketplaces, which mediate the purchase and exchange of data from third parties, have attracted growing attention for reducing the cost and effort of data collection while enabling the trading of diverse datasets. However, a systematic understanding of the interactions between market participants, data, and regulations remains limited. T o address this gap, we propose a Large Language Model-based Multi-Agent System (LLM-MAS) for data marketplaces. In our framework, buyer and seller agents powered by LLMs operate with explicit objectives and autonomously perform strategic actions, such as--planning, searching, purchasing, pricing, and updating data. These agents can reason about market dynamics, forecast future demand, and adapt their strategies accordingly. Unlike conventional model-based simulations, which are typically constrained to predefined rules, LLM-MAS supports broader and more adaptive behavior selection through natural language reasoning. We evaluated the framework via simulation experiments using three distribution-based metrics: (1) the number of purchases per dataset, (2) the number of purchases per buyer, and (3) the number of repeated purchases of the same dataset. The results demonstrate that LLM-MAS more faithfully reproduces trading patterns observed in real data marketplaces compared to traditional approaches, and further captures the emergence and evolution of market trends. Data have emerged as a tradable economic resource, and data marketplaces that mediate the purchase and exchange of datasets from third parties have rapidly expanded [1]. These marketplaces streamline data collection that previously required substantial cost and effort, while also providing organizations and researchers with access to diverse, high-quality datasets. As a result, they are increasingly recognized as critical infrastructures that accelerate innovation based on data that were closed within individual organizations [2]. Despite this progress, our understanding of how interactions among market participants, data, and regulations shape market dynamics remains limited. Smooth and efficient data transactions require well-designed and robust data marketplaces [3].
Seeing isn't Hearing: Benchmarking Vision Language Models at Interpreting Spectrograms
Loakman, Tyler, James, Joseph, Lin, Chenghua
With the rise of Large Language Models (LLMs) and their vision-enabled counterparts (VLMs), numerous works have investigated their capabilities in tasks that fuse the modalities of vision and language. In this work, we benchmark the extent to which VLMs are able to act as highly-trained phoneticians, interpreting spectrograms and waveforms of speech. To do this, we synthesise a novel dataset containing 4k+ English words spoken in isolation alongside stylistically consistent spectrogram and waveform figures. We test the ability of VLMs to understand these representations of speech through a multiple-choice task whereby models must predict the correct phonemic or graphemic transcription of a spoken word when presented amongst 3 distractor transcriptions that have been selected based on their phonemic edit distance to the ground truth. We observe that both zero-shot and finetuned models rarely perform above chance, demonstrating the requirement for specific parametric knowledge of how to interpret such figures, rather than paired samples alone.
GaRLILEO: Gravity-aligned Radar-Leg-Inertial Enhanced Odometry
Noh, Chiyun, Jung, Sangwoo, Kim, Hanjun, Hu, Yafei, Herlant, Laura, Kim, Ayoung
Deployment of legged robots for navigating challenging terrains (e.g., stairs, slopes, and unstructured environments) has gained increasing preference over wheel-based platforms. In such scenarios, accurate odometry estimation is a preliminary requirement for stable locomotion, localization, and mapping. Traditional proprioceptive approaches, which rely on leg kinematics sensor modalities and inertial sensing, suffer from irrepressible vertical drift caused by frequent contact impacts, foot slippage, and vibrations, particularly affected by inaccurate roll and pitch estimation. Existing methods incorporate exteroceptive sensors such as LiDAR or cameras. Further enhancement has been introduced by leveraging gravity vector estimation to add additional observations on roll and pitch, thereby increasing the accuracy of vertical pose estimation. However, these approaches tend to degrade in feature-sparse or repetitive scenes and are prone to errors from double-integrated IMU acceleration. To address these challenges, we propose GaRLILEO, a novel gravity-aligned continuous-time radar-leg-inertial odometry framework. GaRLILEO decouples velocity from the IMU by building a continuous-time ego-velocity spline from SoC radar Doppler and leg kinematics information, enabling seamless sensor fusion which mitigates odometry distortion. In addition, GaRLILEO can reliably capture accurate gravity vectors leveraging a novel soft S2-constrained gravity factor, improving vertical pose accuracy without relying on LiDAR or cameras. Evaluated on a self-collected real-world dataset with diverse indoor-outdoor trajectories, GaRLILEO demonstrates state-of-the-art accuracy, particularly in vertical odometry estimation on stairs and slopes. We open-source both our dataset and algorithm to foster further research in legged robot odometry and SLAM. https://garlileo.github.io/GaRLILEO
Real-time distortion prediction in metallic additive manufacturing via a physics-informed neural operator approach
Tian, Mingxuan, Mu, Haochen, Ding, Donghong, Li, Mengjiao, Ding, Yuhan, Zhao, Jianping
With the development of digital twins and smart manufacturing systems, there is an urgent need for real-time distortion field prediction to control defects in metal Additive Manufacturing (AM). However, numerical simulation methods suffer from high computational cost, long run-times that prevent real-time use, while conventional Machine learning (ML) models struggle to extract spatiotemporal features for long-horizon prediction and fail to decouple thermo-mechanical fields. This paper proposes a Physics-informed Neural Operator (PINO) to predict z and y-direction distortion for the future 15 s. Our method, Physics-informed Deep Operator Network-Recurrent Neural Network (PIDeepONet-RNN) employs trunk and branch network to process temperature history and encode distortion fields, respectively, enabling decoupling of thermo-mechanical responses. By incorporating the heat conduction equation as a soft constraint, the model ensures physical consistency and suppresses unphysical artifacts, thereby establishing a more physically consistent mapping between the thermal history and distortion. This is important because such a basis function, grounded in physical laws, provides a robust and interpretable foundation for predictions. The proposed models are trained and tested using datasets generated from experimentally validated Finite Element Method (FEM). Evaluation shows that the model achieves high accuracy, low error accumulation, time efficiency. The max absolute errors in the z and y-directions are as low as 0.9733 mm and 0.2049 mm, respectively. The error distribution shows high errors in the molten pool but low gradient norms in the deposited and key areas. The performance of PINO surrogate model highlights its potential for real-time long-horizon physics field prediction in controlling defects.
TCM-5CEval: Extended Deep Evaluation Benchmark for LLM's Comprehensive Clinical Research Competence in Traditional Chinese Medicine
Huang, Tianai, Chen, Jiayuan, Lu, Lu, Chen, Pengcheng, Li, Tianbin, Han, Bing, Tang, Wenchao, Xu, Jie, Li, Ming
Large language models (LLMs) have demonstrated exceptional capabilities in general domains, yet their application in highly specialized and culturally-rich fields like Traditional Chinese Medicine (TCM) requires rigorous and nuanced evaluation. Building upon prior foundational work such as TCM-3CEval, which highlighted systemic knowledge gaps and the importance of cultural-contextual alignment, we introduce TCM-5CEval, a more granular and comprehensive benchmark. TCM-5CEval is designed to assess LLMs across five critical dimensions: (1) Core Knowledge (TCM-Exam), (2) Classical Literacy (TCM-LitQA), (3) Clinical Decision-making (TCM-MRCD), (4) Chinese Materia Medica (TCM-CMM), and (5) Clinical Non-pharmacological Therapy (TCM-ClinNPT). We conducted a thorough evaluation of fifteen prominent LLMs, revealing significant performance disparities and identifying top-performing models like deepseek\_r1 and gemini\_2\_5\_pro. Our findings show that while models exhibit proficiency in recalling foundational knowledge, they struggle with the interpretative complexities of classical texts. Critically, permutation-based consistency testing reveals widespread fragilities in model inference. All evaluated models, including the highest-scoring ones, displayed a substantial performance degradation when faced with varied question option ordering, indicating a pervasive sensitivity to positional bias and a lack of robust understanding. TCM-5CEval not only provides a more detailed diagnostic tool for LLM capabilities in TCM but aldso exposes fundamental weaknesses in their reasoning stability. To promote further research and standardized comparison, TCM-5CEval has been uploaded to the Medbench platform, joining its predecessor in the "In-depth Challenge for Comprehensive TCM Abilities" special track.
Local Collaborative Filtering: A Collaborative Filtering Method that Utilizes Local Similarities among Users
To leverage user behavior data from the Internet more effectively in recommender systems, this paper proposes a novel collaborative filtering (CF) method called Local Collaborative Filtering (LCF). LCF utilizes local similarities among users and integrates their data using the law of large numbers (LLN), thereby improving the utilization of user behavior data. Experiments are conducted on the Steam game dataset, and the results of LCF align with real-world needs.
Agent-Oriented Visual Programming for the Web of Things
Burattini, Samuele, Ricci, Alessandro, Mayer, Simon, Vachtsevanou, Danai, Lemee, Jeremy, Ciortea, Andrei, Croatti, Angelo
In this paper we introduce and discuss an approach for multi-agent-oriented visual programming. This aims at enabling individuals without programming experience but with knowledge in specific target domains to design and (re)configure autonomous software. We argue that, compared to procedural programming, it should be simpler for users to create programs when agent abstractions are employed. The underlying rationale is that these abstractions, and specifically the belief-desire-intention architecture that is aligned with human practical reasoning, match more closely with people's everyday experience in interacting with other agents and artifacts in the real world. On top of this, we designed and implemented a visual programming system for agents that hides the technicalities of agent-oriented programming using a blocks-based visual development environment that is built on the JaCaMo platform. To further validate the proposed solution, we integrate the Web of Things (WoT) to let users create autonomous behaviour on top of physical mashups of devices, following the trends in industrial end-user programming. Finally, we report on a pilot user study where we verified that novice users are indeed able to make use of this development environment to create multi-agent systems to solve simple automation tasks.