Large language models (LLMs) often develop learned mechanisms specialized to specific datasets, such as reliance on domain-specific correlations, which yield high-confidence predictions without generalizable reasoning. While beneficial in one setting, these dataset-specific mechanisms typically degrade performance when models encounter novel tasks or distributions. In this work, we introduce a fine-tuning approach designed to enhance generalization by identifying and pruning neurons associated with dataset-specific mechanisms in transformer-based LLMs. Our method employs Integrated Gradients to quantify each neuron's influence on high-confidence predictions, pinpointing those that disproportionately contribute to dataset-specific performance without supporting robust, transferable reasoning. Selectively pruning these neurons compels the model to depend on generalizable representations. Evaluated across multiple-choice benchmarks, our pruning-based fine-tuning significantly enhances performance, surpassing prior (non-pruning) adaptation methods.

This work presents OPENXRD, an open-book pipeline designed for crystallography question answering, which integrates textual prompts with concise supporting content generated by GPT-4.5. Instead of using scanned textbooks, which may lead to copyright issues, OPENXRD generates compact, domain-specific references that help smaller models understand key concepts in X-ray diffraction (XRD). We evaluate OPENXRD on a well-defined set of 217 expert-level XRD questions by comparing different vision-language models, including GPT-4 and LLaVA-based frameworks such as Mistral, LLaMA, and QWEN, under both closed-book (without supporting material) and open-book (with supporting material) conditions. Our experimental results show significant accuracy improvements in models that use the GPT-4.5-generated summaries, particularly those with limited prior training in crystallography. OPENXRD uses knowledge from larger models to fill knowledge gaps in crystallography and shows that AI-generated texts can help smaller models reason more effectively in scientific tasks. While the current version of OPENXRD focuses on text-based inputs, we also explore future extensions such as adding real crystal diagrams or diffraction patterns to improve interpretation in specialized materials science contexts. Overall, OPENXRD shows that specialized open-book systems can be useful in materials science and provides a foundation for broader natural language processing (NLP) tools in critical scientific fields.

Flight delays are a significant challenge in the aviation industry, causing major financial and operational disruptions. To improve passenger experience and reduce revenue loss, flight delay prediction models must be both precise and generalizable across different networks. This paper introduces a novel approach that combines Queue-Theory with a simple attention model, referred to as the Queue-Theory SimAM (QT-SimAM). To validate our model, we used data from the US Bureau of Transportation Statistics, where our proposed QT-SimAM (Bidirectional) model outperformed existing methods with an accuracy of 0.927 and an F1 score of 0.932. To assess transferability, we tested the model on the EUROCONTROL dataset. The results demonstrated strong performance, achieving an accuracy of 0.826 and an F1 score of 0.791. Ultimately, this paper outlines an effective, end-to-end methodology for predicting flight delays. The proposed model's ability to forecast delays with high accuracy across different networks can help reduce passenger anxiety and improve operational decision-making

While poisoning attacks on machine learning models have been extensively studied, the mechanisms by which adversaries can distribute poisoned models at scale remain largely unexplored. In this paper, we shed light on how model leaderboards -- ranked platforms for model discovery and evaluation -- can serve as a powerful channel for adversaries for stealthy large-scale distribution of poisoned models. We present TrojanClimb, a general framework that enables injection of malicious behaviors while maintaining competitive leaderboard performance. We demonstrate its effectiveness across four diverse modalities: text-embedding, text-generation, text-to-speech and text-to-image, showing that adversaries can successfully achieve high leaderboard rankings while embedding arbitrary harmful functionalities, from backdoors to bias injection. Our findings reveal a significant vulnerability in the machine learning ecosystem, highlighting the urgent need to redesign leaderboard evaluation mechanisms to detect and filter malicious (e.g., poisoned) models, while exposing broader security implications for the machine learning community regarding the risks of adopting models from unverified sources.

Introduction: Electronic health records (EHR) are a critical medium through which patient stigmatization is perpetuated among healthcare teams. Methods: We identified linguistic features of doubt markers and stigmatizing labels in MIMIC-III EHR via expanded lexicon matching and supervised learning classifiers. Predictors of rates of linguistic features were assessed using Poisson regression models. Results: We found higher rates of stigmatizing labels per chart among patients who were Black or African American (RR: 1.16), patients with Medicare/Medicaid or government-run insurance (RR: 2.46), self-pay (RR: 2.12), and patients with a variety of stigmatizing disease and mental health conditions. Patterns among doubt markers were similar, though male patients had higher rates of doubt markers (RR: 1.25). We found increased stigmatizing labels used by nurses (RR: 1.40), and social workers (RR: 2.25), with similar patterns of doubt markers. Discussion: Stigmatizing language occurred at higher rates among historically stigmatized patients, perpetuated by multiple provider types.

--Artificial Intelligence-generated content has become increasingly popular, yet its malicious use, particularly the deep-fakes, poses a serious threat to public trust and discourse. While deepfake detection methods achieve high predictive performance, they often exhibit biases across demographic attributes such as ethnicity and gender . In this work, we tackle the challenge of fair deepfake detection, aiming to mitigate these biases while maintaining robust detection capabilities. T o this end, we propose a novel post-processing approach, referred to as Fairness-Oriented Final Layer Input Prioritising (Fair-FLIP), that reweights a trained model's final-layer inputs to reduce subgroup disparities, prioritising those with low variability while demoting highly variable ones. Experimental results comparing Fair-FLIP to both the baseline (without fairness-oriented de-biasing) and state-of-the-art approaches show that Fair-FLIP can enhance fairness metrics by up to 30% while maintaining baseline accuracy, with only a negligible reduction of 0.25%. Code is available on Github: https://github.com/szandala/ The diffusion of Artificial Intelligence (AI)-generated content has accelerated in recent years, driven by the increasing sophistication of generative algorithms [1].

Despite the widespread interest in machine learning (ML), the engineering industry has not yet fully adopted ML-based methods, which has left engineers and stakeholders uncertain about the legal and regulatory frameworks that govern their decisions. This gap remains unaddressed as an engineer's decision-making process, typically governed by professional ethics and practical guidelines, now intersects with complex algorithmic outputs. To bridge this gap, this paper explores how engineers can navigate legal principles and legislative justifications that support and/or contest the deployment of ML technologies. Drawing on recent precedents and experiences gained from other fields, this paper argues that analogical reasoning can provide a basis for embedding ML within existing engineering codes while maintaining professional accountability and meeting safety requirements. In exploring these issues, the discussion focuses on established liability doctrines, such as negligence and product liability, and highlights how courts have evaluated the use of predictive models. We further analyze how legislative bodies and standard-setting organizations can furnish explicit guidance equivalent to prior endorsements of emergent technologies. This exploration stresses the vitality of understanding the interplay between technical justifications and legal precedents for shaping an informed stance on ML's legitimacy in engineering practice. Finally, our analysis catalyzes a legal framework for integrating ML through which stakeholders can critically assess the responsibilities, liabilities, and benefits inherent in ML-driven engineering solutions.

Next-Generation Travel Demand Modeling with a Generative Framework for Household Activity Coordination Xishun Liao 1, Haoxuan Ma 1, Yifan Liu 1, Y uxiang Wei 1, Brian Y ueshuai He 2, Chris Stanford 3, and Jiaqi Ma* 1 Abstract -- Travel demand models are critical tools for planning, policy, and mobility system design. Traditional activity-based models (ABMs), although grounded in behavioral theories, often rely on simplified rules and assumptions, and are costly to develop and difficult to adapt across different regions. This paper presents a learning-based travel demand modeling framework that synthesizes household-coordinated daily activity patterns based on a household's socio-demographic profiles. The whole framework integrates population synthesis, coordinated activity generation, location assignment, and large-scale microscopic traffic simulation into a unified system. It is fully generative, data-driven, scalable, and transferable to other regions. A full-pipeline implementation is conducted in Los Angeles with a 10 million population. Comprehensive validation shows that the model closely replicates real-world mobility patterns and matches the performance of legacy ABMs with significantly reduced modeling cost and greater scalability. With respect to the SCAG ABM benchmark, the origin-destination matrix achieves a cosine similarity of 0.97, and the daily vehicle miles traveled (VMT) in the network yields a 0.006 Jensen-Shannon Divergence (JSD) and a 9.8% mean absolute percentage error (MAPE).

In an era of rampant misinformation, generating reliable news explanations is vital, especially for under-represented languages like Hindi. Lacking robust automated tools, Hindi faces challenges in scaling misinformation detection. To bridge this gap, we propose a novel framework integrating Direct Preference Optimization (DPO) with curriculum learning to align machine-generated explanations with human reasoning. Fact-checked explanations from credible sources serve as preferred responses, while LLM outputs highlight system limitations and serve as non-preferred responses. To refine task-specific alignment, we introduce two key parameters -- Actuality and Finesse -- into the DPO loss function, enhancing explanation quality and consistency. Experiments with LLMs (Mistral, Llama, Gemma) and PLMs (mBART, mT5) confirm the framework's effectiveness in generating coherent, contextually relevant explanations. This scalable approach combats misinformation and extends automated explanation generation to low-resource languages.

Can machines truly think, reason and act in domains like humans? This enduring question continues to shape the pursuit of Artificial General Intelligence (AGI). Despite the growing capabilities of models such as GPT-4.5, DeepSeek, Claude 3.5 Sonnet, Phi-4, and Grok 3, which exhibit multimodal fluency and partial reasoning, these systems remain fundamentally limited by their reliance on token-level prediction and lack of grounded agency. This paper offers a cross-disciplinary synthesis of AGI development, spanning artificial intelligence, cognitive neuroscience, psychology, generative models, and agent-based systems. We analyze the architectural and cognitive foundations of general intelligence, highlighting the role of modular reasoning, persistent memory, and multi-agent coordination. In particular, we emphasize the rise of Agentic RAG frameworks that combine retrieval, planning, and dynamic tool use to enable more adaptive behavior. We discuss generalization strategies, including information compression, test-time adaptation, and training-free methods, as critical pathways toward flexible, domain-agnostic intelligence. Vision-Language Models (VLMs) are reexamined not just as perception modules but as evolving interfaces for embodied understanding and collaborative task completion. We also argue that true intelligence arises not from scale alone but from the integration of memory and reasoning: an orchestration of modular, interactive, and self-improving components where compression enables adaptive behavior. Drawing on advances in neurosymbolic systems, reinforcement learning, and cognitive scaffolding, we explore how recent architectures begin to bridge the gap between statistical learning and goal-directed cognition. Finally, we identify key scientific, technical, and ethical challenges on the path to AGI.