We analyze reasoning in language models during task-specific fine-tuning and draws parallel between reasoning tokens--intermediate steps generated while solving problem and the human working memory. Drawing from cognitive science, we align training dynamics with the Four Stages of Competence: models initially produce incorrect outputs without reasoning, then begin reasoning (but still fail), eventually reason effectively, and finally solve tasks without explicit reasoning. We find that reasoning token length expands as performance improves, peaks at the stage of conscious competence, then declines as the model internalizes the task. Notably, after training, models retain performance even when reasoning is removed--suggesting it scaffolded learning but is no longer needed. This progression offers actionable insights: reasoning token dynamics can serve as a signal for diagnosing training stage, identifying convergence, and guiding early stopping. We propose metrics to track this trajectory and argue that reasoning behavior is valuable for understanding and optimizing reasoning model training.

With the growing use of Large Language Model (LLM)- based Question-Answering (QA) systems in education, it is critical to evaluate their performance across individual pipeline components. In this work, we introduce EduMod-LLM, a modular function-calling LLM pipeline, and present a comprehensive evaluation along three key axes: function calling strategies, retrieval methods, and generative language models. Our framework enables fine-grained analysis by isolating and assessing each component. We benchmark function-calling performance across LLMs, compare our novel structure-aware retrieval method to vector-based and LLM-scoring baselines, and evaluate various LLMs for response synthesis. This modular approach reveals specific failure modes and performance patterns, supporting the development of interpretable and effective educational QA systems. Our findings demonstrate the value of modular function calling in improving system transparency and pedagogical alignment.

We present the first large-scale analysis of AI foundation model usage in science - not just citations or keywords. We find that adoption has grown rapidly, at nearly-exponential rates, with the highest uptake in Linguistics, Computer Science, and Engineering. Vision models are the most used foundation models in science, although language models' share is growing. Open-weight models dominate. As AI builders increase the parameter counts of their models, scientists have followed suit but at a much slower rate: in 2013, the median foundation model built was 7.7x larger than the median one adopted in science, by 2024 this had jumped to 26x. We also present suggestive evidence that scientists' use of these smaller models may be limiting them from getting the full benefits of AI-enabled science, as papers that use larger models appear in higher-impact journals and accrue more citations.

AI-assisted report generation offers the opportunity to reduce radiologists' workload stemming from expanded screening guidelines, complex cases and workforce shortages, while maintaining diagnostic accuracy. In addition to describing pathological findings in chest X-ray reports, interpreting lines and tubes (L&T) is demanding and repetitive for radiologists, especially with high patient volumes. We introduce MAIRA-X, a clinically evaluated multimodal AI model for longitudinal chest X-ray (CXR) report generation, that encompasses both clinical findings and L&T reporting. Developed using a large-scale, multi-site, longitudinal dataset of 3.1 million studies (comprising 6 million images from 806k patients) from Mayo Clinic, MAIRA-X was evaluated on three holdout datasets and the public MIMIC-CXR dataset, where it significantly improved AI-generated reports over the state of the art on lexical quality, clinical correctness, and L&T-related elements. A novel L&T-specific metrics framework was developed to assess accuracy in reporting attributes such as type, longitudinal change and placement. A first-of-its-kind retrospective user evaluation study was conducted with nine radiologists of varying experience, who blindly reviewed 600 studies from distinct subjects. The user study found comparable rates of critical errors (3.0% for original vs. 4.6% for AI-generated reports) and a similar rate of acceptable sentences (97.8% for original vs. 97.4% for AI-generated reports), marking a significant improvement over prior user studies with larger gaps and higher error rates. Our results suggest that MAIRA-X can effectively assist radiologists, particularly in high-volume clinical settings.

Fine-tuning large language models is essential for task-specific adaptation, yet it remains computationally prohibitive. Parameter-Efficient Fine-Tuning (PEFT) methods have emerged as a solution, but current approaches typically ignore the distinct roles of model components and the heterogeneous importance across layers, thereby limiting adaptation efficiency. Motivated by the observation that Rotary Position Embeddings (RoPE) induce critical activations in the low-frequency dimensions of attention states, we propose RoPE-aware Selective Adaptation (RoSA), a novel PEFT framework that allocates trainable parameters in a more targeted and effective manner. RoSA comprises a RoPE-aware Attention Enhancement (RoAE) module, which selectively enhances the low-frequency components of RoPE-influenced attention states, and a Dynamic Layer Selection (DLS) strategy that adaptively identifies and updates the most critical layers based on LayerNorm gradient norms. By combining dimension-wise enhancement with layer-wise adaptation, RoSA achieves more targeted and efficient fine-tuning. Extensive experiments on fifteen commonsense and arithmetic benchmarks demonstrate that RoSA outperforms existing mainstream PEFT methods under comparable trainable parameters.

Humor, as both a creative human activity and a social binding mechanism, has long posed a major challenge for AI generation. Although producing humor requires complex cognitive reasoning and social understanding, theories of humor suggest that it follows learnable patterns and structures, making it theoretically possible for generative models to acquire them implicitly. In recent years, multimodal humor has become a prevalent form of online communication, especially among Gen Z, highlighting the need for AI systems capable of integrating visual understanding with humorous language generation. However, existing data-driven approaches lack explicit modeling or theoretical grounding of humor, often producing literal descriptions that fail to capture its underlying cognitive mechanisms, resulting in the generated image descriptions that are fluent but lack genuine humor or cognitive depth. To address this limitation, we propose HUMORCHAIN (HUmor-guided Multi-step Orchestrated Reasoning Chain for Image Captioning), a theory-guided multi-stage reasoning framework. It integrates visual semantic parsing, humor- and psychology-based reasoning, and a fine-tuned discriminator for humor evaluation, forming an interpretable and controllable cognitive reasoning chain. To the best of our knowledge, this is the first work to explicitly embed cognitive structures from humor theories into multimodal humor generation, enabling a structured reasoning process from visual understanding to humor creation. Experiments on Meme-Image-No-Text, Oogiri-GO, and OxfordTVG-HIC datasets show that HUMORCHAIN outperforms state-of-the-art baselines in human humor preference, Elo/BT scores, and semantic diversity, demonstrating that theory-driven structured reasoning enables large language models to generate humor aligned with human perception.

We present the results of cognitive tests on conceptual combinations, performed using specific Large Language Models (LLMs) as test subjects. In the first test, performed with ChatGPT and Gemini, we show that Bell's inequalities are significantly violated, which indicates the presence of 'quantum entanglement' in the tested concepts. In the second test, also performed using ChatGPT and Gemini, we instead identify the presence of 'Bose-Einstein statistics', rather than the intuitively expected 'Maxwell-Boltzmann statistics', in the distribution of the words contained in large-size texts. Interestingly, these findings mirror the results previously obtained in both cognitive tests with human participants and information retrieval tests on large corpora. Taken together, they point to the 'systematic emergence of quantum structures in conceptual-linguistic domains', regardless of whether the cognitive agent is human or artificial. Although LLMs are classified as neural networks for historical reasons, we believe that a more essential form of knowledge organization takes place in the distributive semantic structure of vector spaces built on top of the neural network. It is this meaning-bearing structure that lends itself to a phenomenon of evolutionary convergence between human cognition and language, slowly established through biological evolution, and LLM cognition and language, emerging much more rapidly as a result of self-learning and training. We analyze various aspects and examples that contain evidence supporting the above hypothesis. We also advance a unifying framework that explains the pervasive quantum organization of meaning that we identify.

Lightweight language models remain attractive for on-device and privacy-sensitive applications, but their responses are highly sensitive to prompt quality. For open-ended generation, non-expert users often lack the knowledge or time to consistently craft high-quality prompts, leading them to rely on prompt optimization tools. However, a key challenge is ensuring the optimized prompts genuinely align with users' original intents and preferences. We introduce PromptTailor, a system for controllable prompt generation for open-ended text that improves model output quality by intent-aligned prompt synthesis. PromptTailor expands minimal user instructions into rich, domain-aware prompts while preserving the user's stated preferences. The system is a quantized Llama3-8B model fine-tuned with a lightweight LoRA adapter on 12,300 prompt-refinement dialogues spanning 41 everyday domains, distilled from three stronger LLMs. The adapter attaches to any Llama3-8B base, enabling edge deployment. In human and LLM-judge evaluations across multiple target models and optimization baselines, PromptTailor yields higher preference rates than chain-of-thought prompting and matches or surpasses state-of-the-art prompt optimization methods while requiring fewer model calls (e.g., 3 vs. 9). These results show that a compact student, guided by powerful teachers, can learn effective prompt-generation strategies that enhance response quality while maintaining alignment with user intent.

Objective This study introduces the Alzheimer's Disease Common Data Element Ontology for Clinical Trials (AD-CDO), a lightweight, semantically enriched ontology designed to represent and standardize key eligibility criteria concepts in Alzheimer's disease (AD) clinical trials. Materials and Methods We extracted high-frequency concepts from more than 1,500 AD clinical trials on ClinicalTrials.gov and organized them into seven semantic categories: Disease, Medication, Diagnostic Test, Procedure, Social Determinants of Health, Rating Criteria, and Fertility. Each concept was annotated with standard biomedical vocabularies, including the UMLS, OMOP Standardized Vocabularies, DrugBank, NDC, and NLM VSAC value sets. To balance coverage and manageability, we applied the Jenks Natural Breaks method to identify an optimal set of representative concepts. Results The optimized AD-CDO achieved over 63% coverage of extracted trial concepts while maintaining interpretability and compactness. The ontology effectively captured the most frequent and clinically meaningful entities used in AD eligibility criteria. We demonstrated AD-CDO's practical utility through two use cases: (a) an ontology-driven trial simulation system for formal modeling and virtual execution of clinical trials, and (b) an entity normalization task mapping raw clinical text to ontology-aligned terms, enabling consistency and integration with EHR data. Discussion AD-CDO bridges the gap between broad biomedical ontologies and task-specific trial modeling needs. It supports multiple downstream applications, including phenotyping algorithm development, cohort identification, and structured data integration. Conclusion By harmonizing essential eligibility entities and aligning them with standardized vocabularies, AD-CDO provides a versatile foundation for ontology-driven AD clinical trial research.

The use of Large Language Models (LLMs) for simulating human perspectives via persona prompting is gaining traction in computational social science. However, well-curated, empirically grounded persona collections remain scarce, limiting the accuracy and representativeness of such simulations. Here we introduce the German General Personas (GGP) collection, a comprehensive and representative persona prompt collection built from the German General Social Survey (ALLBUS). The GGP and its persona prompts are designed to be easily plugged into prompts for all types of LLMs and tasks, steering models to generate responses aligned with the underlying German population. We evaluate GGP by prompting various LLMs to simulate survey response distributions across diverse topics, demonstrating that GGP-guided LLMs outperform state-of-the-art classifiers, particularly under data scarcity. Furthermore, we analyze how the representativity and attribute selection within persona prompts affect alignment with population responses. Our findings suggest that GGP provides a potentially valuable resource for research on LLM-based social simulations that enables more systematic explorations of population-aligned persona prompting in NLP and social science research.