We applied machine learning to the unmet medical need of rapid and accurate diagnosis and prognosis of acute infections and sepsis in emergency departments. Our solution consists of a Myrna (TM) Instrument and embedded TriVerity (TM) classifiers. The instrument measures abundances of 29 messenger RNAs in patient's blood, subsequently used as features for machine learning. The classifiers convert the input features to an intuitive test report comprising the separate likelihoods of (1) a bacterial infection (2) a viral infection, and (3) severity (need for Intensive Care Unit-level care). In internal validation, the system achieved AUROC = 0.83 on the three-class disease diagnosis (bacterial, viral, or non-infected) and AUROC = 0.77 on binary prognosis of disease severity. The Myrna, TriVerity system was granted breakthrough device designation by the United States Food and Drug Administration (FDA). This engineering manuscript teaches the standard and novel machine learning methods used to translate an academic research concept to a clinical product aimed at improving patient care, and discusses lessons learned.

We uncover a surprising multilingual bias occurring in a popular class of multimodal vision-language models (VLMs). Including an image in the query to a LLaVA-style VLM significantly increases the likelihood of the model returning an English response, regardless of the language of the query. This paper investigates the causes of this loss with a two-pronged approach that combines extensive ablation of the design space with a mechanistic analysis of the models' internal representations of image and text inputs. Both approaches indicate that the issue stems in the language modelling component of the LLaVA model. Statistically, we find that switching the language backbone for a bilingual language model has the strongest effect on reducing this error. Mechanistically, we provide compelling evidence that visual inputs are not mapped to a similar space as text ones, and that intervening on intermediary attention layers can reduce this bias. Our findings provide important insights to researchers and engineers seeking to understand the crossover between multimodal and multilingual spaces, and contribute to the goal of developing capable and inclusive VLMs for non-English contexts.

In this work, we present a comprehensive three-phase study to examine (1) the effectiveness of large multimodal models (LMMs) in recognizing cultural contexts; (2) the accuracy of their representations of diverse cultures; and (3) their ability to adapt content across cultural boundaries. We first introduce Dalle Street, a large-scale dataset generated by DALL-E 3 and validated by humans, containing 9,935 images of 67 countries and 10 concept classes. We reveal disparities in cultural understanding at the sub-region level with both open-weight (LLaVA) and closed-source (GPT-4V) models on Dalle Street and other existing benchmarks. Next, we assess models' deeper culture understanding by an artifact extraction task and identify over 18,000 artifacts associated with different countries. Finally, we propose a highly composable pipeline, CultureAdapt, to adapt images from culture to culture. Our findings reveal a nuanced picture of the cultural competence of LMMs, highlighting the need to develop culture-aware systems. Dataset and code are available at https://github.com/iamshnoo/crossroads

Decoder-only large language models (LLMs) excel in high-resource languages across various tasks through few-shot or even zero-shot in-context learning (ICL). However, their performance often does not transfer well to low-resource languages, especially those written in non-Latin scripts. Inspired by recent work that leverages transliteration in encoder-only models, we investigate whether transliteration is also effective in improving LLMs' performance for low-resource languages written in non-Latin scripts. To this end, we propose three prompt templates, where the target-language text is represented in (1) its original script, (2) Latin script, or (3) both. We apply these methods to several representative LLMs of different sizes on various tasks including text classification and sequential labeling. Our findings show that the effectiveness of transliteration varies by task type and model size. For instance, all models benefit from transliterations for sequential labeling (with increases of up to 25%).

Personalized Dialogue Generation (PDG) aims to create coherent responses according to roles or personas. Traditional PDG relies on external role data, which can be scarce and raise privacy concerns. Approaches address these issues by extracting role information from dialogue history, which often fail to generically model roles in continuous space. To overcome these limitations, we introduce a novel framework \textbf{MO}dels \textbf{R}oles from \textbf{P}ersonalized Dialogue \textbf{H}istory by \textbf{E}xploring and \textbf{U}tilizing Latent \textbf{S}pace (MORPHEUS) through a three-stage training process. Specifically, we create a persona codebook to represent roles in latent space compactly, and this codebook is used to construct a posterior distribution of role information. This method enables the model to generalize across roles, allowing the generation of personalized dialogues even for unseen roles. Experiments on both Chinese and English datasets demonstrate that MORPHEUS enhances the extraction of role information, and improves response generation without external role data. Additionally, MORPHEUS can be considered an efficient fine-tuning for large language models.

MLKD-BERT conducts a (Liu et al., 2019). The PLM usually has large number two-stage distillation for feature-level as well as of parameters and long inference time, making relation-level knowledge, with 6 distillation loss it inapplicable to resource-limited devices and realtime functions designed for embedding layer, Transformer scenarios. Therefore, it is crucial to reduce layers, and prediction layer. Compared with PLM's storage and computation overhead while previous works, we have made two main contributions: retaining its performance. Knowledge distillation (Hinton et al., 2015) is an effective technique for PLM compression. In knowledge distillation, a In addition to feature-level knowledge, our smaller compact student model is trained, under student model learns valuable relation-level the guidance of a larger complicated teacher model, knowledge (relation among tokens and relation to keep similar model performance.

Conversational Query Reformulation (CQR) has significantly advanced in addressing the challenges of conversational search, particularly those stemming from the latent user intent and the need for historical context. Recent works aimed to boost the performance of CRQ through alignment. However, they are designed for one specific retrieval system, which potentially results in poor generalization. To overcome this limitation, we present a novel framework AdaCQR. By aligning reformulation models with both term-based and semantic-based retrieval systems, AdaCQR enhances the generalizability of information-seeking queries across diverse retrieval environments through a dual-phase training strategy. We also developed two effective approaches for acquiring superior labels and diverse input candidates, boosting the efficiency and robustness of the framework. Experimental evaluations on the TopiOCQA and QReCC datasets demonstrate that AdaCQR significantly outperforms existing methods, offering both quantitative and qualitative improvements in conversational query reformulation.

An adverse drug effect (ADE) is any harmful event resulting from medical drug treatment. Despite their importance, ADEs are often under-reported in official channels. Some research has therefore turned to detecting discussions of ADEs in social media. Impressive results have been achieved in various attempts to detect ADEs. In a high-stakes domain such as medicine, however, an in-depth evaluation of a model's abilities is crucial. We address the issue of thorough performance evaluation in English-language ADE detection with hand-crafted templates for four capabilities: Temporal order, negation, sentiment, and beneficial effect. We find that models with similar performance on held-out test sets have varying results on these capabilities.

Sentence embeddings from transformer models encode in a fixed length vector much linguistic information. We explore the hypothesis that these embeddings consist of overlapping layers of information that can be separated, and on which specific types of information -- such as information about chunks and their structural and semantic properties -- can be detected. We show that this is the case using a dataset consisting of sentences with known chunk structure, and two linguistic intelligence datasets, solving which relies on detecting chunks and their grammatical number, and respectively, their semantic roles, and through analyses of the performance on the tasks and of the internal representations built during learning.

As large language models (LLMs) are deployed in more and more real-world situations, it is crucial to understand their decision-making when faced with moral dilemmas. Inspired by a large-scale cross-cultural study of human moral preferences, "The Moral Machine Experiment", we set up the same set of moral choices for LLMs. We translate 1K vignettes of moral dilemmas, parametrically varied across key axes, into 100+ languages, and reveal the preferences of LLMs in each of these languages. We then compare the responses of LLMs to that of human speakers of those languages, harnessing a dataset of 40 million human moral judgments. We discover that LLMs are more aligned with human preferences in languages such as English, Korean, Hungarian, and Chinese, but less aligned in languages such as Hindi and Somali (in Africa). Moreover, we characterize the explanations LLMs give for their moral choices and find that fairness is the most dominant supporting reason behind GPT-4's decisions and utilitarianism by GPT-3. We also discover "language inequality" (which we define as the model's different development levels in different languages) in a series of meta-properties of moral decision making.