Deep learning has emerged as a pivotal tool for accelerating research in the life sciences, with the low-level processing of biomedical images (e.g., registration, fusion, restoration, super-resolution) being one of its most critical applications. Platforms such as ImageJ (Fiji) and napari have enabled the development of customized plugins for various models. However, these plugins are typically based on models that are limited to specific tasks and datasets, making them less practical for biologists. To address this challenge, we introduce Orochi, the first application-oriented, efficient, and versatile image processor designed to overcome these limitations. Orochi is pre-trained on patches/volumes extracted from the raw data of over 100 publicly available studies using our Random Multi-scale Sampling strategy.

Deep learning has emerged as a pivotal tool for accelerating research in the life sciences, with the low-level processing of biomedical images (e.g., registration, fusion, restoration, super-resolution) being one of its most critical applications. Platforms such as ImageJ (Fiji) and napari have enabled the development of customized plugins for various models. However, these plugins are typically based on models that are limited to specific tasks and datasets, making them less practical for biologists.

The ocean’s bad boys don’t just cruise alone—they have preferred swimming partners.

The complete list may be seen in Table 8. Here are a few general notes about these strings: 1. Based on their recommendations, we did the following: 1. zh, zh_Latn: This resulted in the special filters described below. URLs) the corpora were in languages different from the LangID predictions. This is mainly mis-rendered PDFs and may have practical applications for denoising, or for decoding such garbled PDFs.

Theoptimalbaseline, however, israrelyusedinpractice (Sutton & Barto (2018); foran exception, see (Peters & Schaal, 2008)). Equation (1) thentakesthefollowingform: r E R(x)= E (R(x) B)r log (x).

As we look back on 2025, the world experienced a year of both remarkable achievement and profound challenge in global health. Multilateralism, science and solidarity were tested as never before, underscoring a fundamental truth: International cooperation is not optional. It is essential if we are to protect and promote health for everyone, everywhere in 2026 and beyond. Perhaps the most significant milestone was the adoption by WHO Member States of the Pandemic Agreement, a landmark step towards making the world safer from future pandemics. Alongside this, amendments to the International Health Regulations came into force, including a new "pandemic emergency" alert level designed to trigger stronger global cooperation.

Synthetic data generation is an important tool for privacy-preserving data sharing. While diffusion models have set recent benchmarks, flow matching (FM) offers a promising alternative. This paper presents different ways to implement flow matching for tabular data synthesis. We provide a comprehensive empirical study that compares flow matching (FM and variational FM) with a state-of-the-art diffusion method (TabDDPM and TabSyn) in tabular data synthesis. We evaluate both the standard Optimal Transport (OT) and the Variance Preserving (VP) probability paths, and also compare deterministic and stochastic samplers -- something possible when learning to generate using \textit{variational} flow matching -- characterising the empirical relationship between data utility and privacy risk. Our key findings reveal that flow matching, particularly TabbyFlow, outperforms diffusion baselines. Flow matching methods also achieves better performance with remarkably low function evaluations ($\leq$ 100 steps), offering a substantial computational advantage. The choice of probability path is also crucial, as using the OT path demonstrates superior performance, while VP has potential for producing synthetic data with lower disclosure risk. Lastly, our results show that making flows stochastic not only preserves marginal distributions but, in some instances, enables the generation of high utility synthetic data with reduced disclosure risk.