Parents in north London have been told their children could be excluded from school if they are not fully vaccinated against measles amid an outbreak of the highly-contagious disease. Unvaccinated pupils identified as close contacts of people with measles could be excluded for 21 days in accordance with national guidelines, Enfield Council said in a letter to all parents in the borough in late January. At least 34 children have contracted measles in Enfield so far this year, the UK Health Security Agency (UKHSA) has said, and a number sent to hospital. A local health chief meanwhile told the BBC: We are worried because actually, this is a significantly increased number than what we're used to. Asking unvaccinated, close contacts of measles cases to stay off school is fairly standard practice when there are local outbreaks.

New studies reveal that potential COVID vaccine health risks, including kidney injury and respiratory infections, but experts urge caution in interpreting findings.

Large Language Models (LLMs) distinguish themselves by quickly delivering information and providing personalized responses through natural language prompts. However, they also infer user demographics, which can raise ethical concerns about bias and implicit personalization and create an echo chamber effect. This study aims to explore how inferred political views impact the responses of ChatGPT globally, regardless of the chat session. We also investigate how custom instruction and memory features alter responses in ChatGPT, considering the influence of political orientation. We developed three personas (two politically oriented and one neutral), each with four statements reflecting their viewpoints on DEI programs, abortion, gun rights, and vaccination. We convey the personas' remarks to ChatGPT using memory and custom instructions, allowing it to infer their political perspectives without directly stating them. We then ask eight questions to reveal differences in worldview among the personas and conduct a qualitative analysis of the responses. Our findings indicate that responses are aligned with the inferred political views of the personas, showing varied reasoning and vocabulary, even when discussing similar topics. We also find the inference happening with explicit custom instructions and the implicit memory feature in similar ways. Analyzing response similarities reveals that the closest matches occur between the democratic persona with custom instruction and the neutral persona, supporting the observation that ChatGPT's outputs lean left.

Social media platforms such as Twitter (now X) provide rich data for analyzing public discourse, especially during crises such as the COVID-19 pandemic. However, the brevity, informality, and noise of social media short texts often hinder the effectiveness of traditional topic modeling, producing incoherent or redundant topics that are often difficult to interpret. To address these challenges, we have developed \emph{TM-Rephrase}, a model-agnostic framework that leverages large language models (LLMs) to rephrase raw tweets into more standardized and formal language prior to topic modeling. Using a dataset of 25,027 COVID-19-related Twitter posts, we investigate the effects of two rephrasing strategies, general- and colloquial-to-formal-rephrasing, on multiple topic modeling methods. Results demonstrate that \emph{TM-Rephrase} improves three metrics measuring topic modeling performance (i.e., topic coherence, topic uniqueness, and topic diversity) while reducing topic redundancy of most topic modeling algorithms, with the colloquial-to-formal strategy yielding the greatest performance gains and especially for the Latent Dirichlet Allocation (LDA) algorithm. This study contributes to a model-agnostic approach to enhancing topic modeling in public health related social media analysis, with broad implications for improved understanding of public discourse in health crisis as well as other important domains.

In an era where public health is increasingly influenced by information shared on social media, combatting vaccine skepticism and misinformation has become a critical societal goal. Misleading narratives around vaccination have spread widely, creating barriers to achieving high immunisation rates and undermining trust in health recommendations. While efforts to detect misinformation have made significant progress, the generation of real time counter-arguments tailored to debunk such claims remains an insufficiently explored area. In this work, we explore the capabilities of LLMs to generate sound counter-argument rebuttals to vaccine misinformation. Building on prior research in misinformation debunking, we experiment with various prompting strategies and fine-tuning approaches to optimise counter-argument generation. Additionally, we train classifiers to categorise anti-vaccine tweets into multi-labeled categories such as concerns about vaccine efficacy, side effects, and political influences allowing for more context aware rebuttals. Our evaluation, conducted through human judgment, LLM based assessments, and automatic metrics, reveals strong alignment across these methods. Our findings demonstrate that integrating label descriptions and structured fine-tuning enhances counter-argument effectiveness, offering a promising approach for mitigating vaccine misinformation at scale.

The COVID-19 pandemic underscored a critical need for intervention strategies that balance disease containment with socioeconomic stability. We approach this challenge by designing a framework for modeling and evaluating disease-spread prevention strategies. Our framework leverages multi-objective reinforcement learning (MORL) - a formulation necessitated by competing objectives - combined with a new stochastic differential equation (SDE) pandemic simulator, calibrated and validated against global COVID-19 data. Our simulator reproduces national-scale pandemic dynamics with orders of magnitude higher fidelity than other models commonly used in reinforcement learning (RL) approaches to pandemic intervention. Training a Pareto-Conditioned Network (PCN) agent on this simulator, we illustrate the direct policy trade-offs between epidemiological control and economic stability for COVID-19. Furthermore, we demonstrate the framework's generality by extending it to pathogens with different epidemiological profiles, such as polio and influenza, and show how these profiles lead the agent to discover fundamentally different intervention policies. To ground our work in contemporary policymaking challenges, we apply the model to measles outbreaks, quantifying how a modest 5% drop in vaccination coverage necessitates significantly more stringent and costly interventions to curb disease spread. This work provides a robust and adaptable framework to support transparent, evidence-based policymaking for mitigating public health crises.

The vaccine advisory group ACIP, not all members of which seemed to know what the group does, recommended to the CDC that combined MMRV shots not be given before age 4. A federal vaccine advisory committee made of members hand-picked by Health and Human Services Secretary Robert F. Kennedy Jr. recommended in an 8-3 vote on Thursday that the combined measles, mumps, rubella and varicella (MMRV) vaccine should not be given before age four, citing long-known evidence that shows a slightly increased risk for febrile seizures in that age group. Experts say that while frightening, febrile seizures--which are uncommon after vaccination--are usually short-lived and harmless, and removing the option for parents could cause a decline in immunization rates against measles, mumps, and rubella, some of the most dangerous childhood diseases. Known as the Advisory Committee on Immunization Practices, or ACIP, the group provides recommendations to the US Centers for Disease Control and Prevention on vaccine usage. These recommendations are typically adopted by CDC and have an impact on state vaccine requirements for school, insurance coverage of vaccines, and pharmacy access--something at least one member of the panel seemed to be unaware of. Thursday's vote is part of a new shift in vaccine policy being spearheaded by Kennedy, a longtime anti-vaccine activist.

Fox News senior medical analyst Dr. Marc Siegel shares his perspective on whether the mosquito-borne virus in China will spread to the United States and how AI can be detrimental to children's and young adults' mental health on'Fox Report.' The U.S. Centers for Disease Control and Prevention (CDC) is warning that travelers to China face an "enhanced" risk of contracting a virus spread by mosquitoes. There has been an outbreak of chikungunya in Guangdong Province, which can cause fever, joint pain, headache, muscle pain, joint swelling, and rash. Recently, the CDC raised the warning related to chikungunya in China from Level 1: "Practice Usual Precautions" to Level 2: "Practice Enhanced Precautions." The CDC says there are no medicines to treat chikungunya, and recommends preventing it by wearing insect repellent, wearing long sleeves and pants, or staying in places that have air conditioning or screens on the windows and doors.

Modelling disease outbreak models remains challenging due to incomplete surveillance data, noise, and limited access to standardized datasets. We have created BIGBOY1.2, an open synthetic dataset generator that creates configurable epidemic time series and population-level trajectories suitable for benchmarking modelling, forecasting, and visualisation. The framework supports SEIR and SIR-like compartmental logic, custom seasonality, and noise injection to mimic real reporting artifacts. BIGBOY1.2 can produce datasets with diverse characteristics, making it suitable for comparing traditional epidemiological models (e.g., SIR, SEIR) with modern machine learning approaches (e.g., SVM, neural networks).

The rapid development of COVID-19 vaccines has showcased the global community's ability to combat infectious diseases. However, the need for post-licensure surveillance systems has grown due to the limited window for safety data collection in clinical trials and early widespread implementation. This study aims to employ Natural Language Processing (NLP) techniques and Active Learning (AL) to rapidly develop a classifier that detects potential vaccine safety issues from emergency department (ED) notes. ED triage notes, containing expert, succinct vital patient information at the point of entry to health systems, can significantly contribute to timely vaccine safety signal surveillance. While keyword-based classification can be effective, it may yield false positives and demand extensive keyword modifications. This is exacerbated by the infrequency of vaccination-related ED presentations and their similarity to other reasons for ED visits. NLP offers a more accurate and efficient alternative, albeit requiring annotated data, which is often scarce in the medical field. Active learning optimizes the annotation process and the quality of annotated data, which can result in faster model implementation and improved model performance. This work combines active learning, data augmentation, and active learning and evaluation techniques to create a classifier that is used to enhance vaccine safety surveillance from ED triage notes.