Automation of sleep analysis, including both macrostructural (sleep stages) and microstructural (e.g., sleep spindles) elements, promises to enable large-scale sleep studies and to reduce variance due to inter-rater incongruencies. While individual steps, such as sleep staging and spindle detection, have been studied separately, the feasibility of automating multi-step sleep analysis remains unclear. Here, we evaluate whether a fully automated analysis using state-of-the-art machine learning models for sleep staging (RobustSleepNet) and subsequent spindle detection (SUMOv2) can replicate findings from an expert-based study of bipolar disorder. The automated analysis qualitatively reproduced key findings from the expert-based study, including significant differences in fast spindle densities between bipolar patients and healthy controls, accomplishing in minutes what previously took months to complete manually. While the results of the automated analysis differed quantitatively from the expert-based study, possibly due to biases between expert raters or between raters and the models, the models individually performed at or above inter-rater agreement for both sleep staging and spindle detection. Our results demonstrate that fully automated approaches have the potential to facilitate large-scale sleep research. We are providing public access to the tools used in our automated analysis by sharing our code and introducing SomnoBot, a privacy-preserving sleep analysis platform.

Recent foundation models are capable of handling multiple machine learning (ML) tasks and multiple data modalities with the unified base model structure and several specialized model components. However, the development of such multi-task (MT) multi-modal (MM) models poses significant model management challenges to existing training systems. Due to the sophisticated model architecture and the heterogeneous workloads of different ML tasks and data modalities, training these models usually requires massive GPU resources and suffers from sub-optimal system efficiency. In this paper, we investigate how to achieve high-performance training of large-scale MT MM models through data heterogeneity-aware model management optimization. The key idea is to decompose the model execution into stages and address the joint optimization problem sequentially, including both heterogeneity-aware workload parallelization and dependency-driven execution scheduling. Based on this, we build a prototype system and evaluate it on various large MT MM models. Experiments demonstrate the superior performance and efficiency of our system, with speedup ratio up to 71% compared to state-of-the-art training systems.

Objective: Sleep spindles contain crucial brain dynamics information. We introduce the novel non-linear time-frequency analysis tool 'Concentration of Frequency and Time' (ConceFT) to create an interpretable automated algorithm for sleep spindle annotation in EEG data and to measure spindle instantaneous frequencies (IFs). Methods: ConceFT effectively reduces stochastic EEG influence, enhancing spindle visibility in the time-frequency representation. Our automated spindle detection algorithm, ConceFT-Spindle (ConceFT-S), is compared to A7 (non-deep learning) and SUMO (deep learning) using Dream and MASS benchmark databases. We also quantify spindle IF dynamics. Results: ConceFT-S achieves F1 scores of 0.749 in Dream and 0.786 in MASS, which is equivalent to or surpass A7 and SUMO with statistical significance. We reveal that spindle IF is generally nonlinear. Conclusion: ConceFT offers an accurate, interpretable EEG-based sleep spindle detection algorithm and enables spindle IF quantification.

With NASA aiming to get humans to Mars by 2030, the idea of a long-term settlement on the Red Planet is getting closer to reality and scientists are working on innovated ways to power these habitats. Researchers in the Netherlands propose using massive kites to harness high Martian winds that would transformed into energy for colonists. The kite is attached by cable to a spindle. Similar kites are being developed to harness wind power on Earth, but these would be much larger, with a surface area of 530 square feet. Wind turbines and batteries are too heavy to bring to Mars via rocket, and the planet doesn't get enough sunlight to consider solar power.

This is, what we aim to at our own factories. Read my introduction to a series of blogposts how we do this. Harnessing the power of artificial intelligence (AI), engineers at our manufacturing plant in Amberg can predict when a key component is likely to fail – up to 36 hours before the failure actually happens. This allows them to react in plenty of time to avoid a costly breakdown of the machine. In our electronics manufacturing facility in Amberg, we have several PCB cutting machines that are deployed for a number of our SIMATIC products – including the S7-300 and ET 200. As this machines work, aggressive milling dust builds up and, eventually, the spindles bearing jams.

Background: Electroencephalography (EEG) monitors brain activity during sleep and is used to identify sleep disorders. In sleep medicine, clinicians interpret raw EEG signals in so-called sleep stages, which are assigned by experts to every 30s window of signal. For diagnosis, they also rely on shorter prototypical micro-architecture events which exhibit variable durations and shapes, such as spindles, K-complexes or arousals. Annotating such events is traditionally performed by a trained sleep expert, making the process time consuming, tedious and subject to inter-scorer variability. To automate this procedure, various methods have been developed, yet these are event-specific and rely on the extraction of hand-crafted features. New method: We propose a novel deep learning architecure called Dreem One Shot Event Detector (DOSED). DOSED jointly predicts locations, durations and types of events in EEG time series. The proposed approach, applied here on sleep related micro-architecture events, is inspired by object detectors developed for computer vision such as YOLO and SSD. It relies on a convolutional neural network that builds a feature representation from raw EEG signals, as well as two modules performing localization and classification respectively. Results and comparison with other methods: The proposed approach is tested on 4 datasets and 3 types of events (spindles, K-complexes, arousals) and compared to the current state-of-the-art detection algorithms. Conclusions: Results demonstrate the versatility of this new approach and improved performance compared to the current state-of-the-art detection methods.

Non-rapid eye movement sleep, or NREM, is, collectively, sleep stages 1–3, previously known as stages 1–4. Rapid eye movement sleep (REM) is not included. There are distinct electroencephalographic and other characteristics seen in each stage. Unlike REM sleep, there is usually little or no eye movement during these stages. Dreaming is rare during NREM sleep, and muscles are not paralyzed as in REM sleep.