COVID-19 continues to be considered an endemic disease in spite of the World Health Organization's declaration that the pandemic is over. This pandemic has disrupted people's lives in unprecedented ways and caused widespread morbidity and mortality. As a result, it is important for emergency physicians to identify patients with a higher mortality risk in order to prioritize hospital equipment, especially in areas with limited medical services. The collected data from patients is beneficial to predict the outcome of COVID-19 cases, although there is a question about which data makes the most accurate predictions. Therefore, this study aims to accomplish two main objectives. First, we want to examine whether deep learning algorithms can predict a patient's morality. Second, we investigated the impact of Clinical and RT-PCR on prediction to determine which one is more reliable. We defined four stages with different feature sets and used interpretable deep learning methods to build appropriate model. Based on results, the deep neural decision forest performed the best across all stages and proved its capability to predict the recovery and death of patients. Additionally, results indicate that Clinical alone (without the use of RT-PCR) is the most effective method of diagnosis, with an accuracy of 80%. It is important to document and understand experiences from the COVID-19 pandemic in order to aid future medical efforts. This study can provide guidance for medical professionals in the event of a crisis or outbreak similar to COVID-19. Keywords: Machine Learning, Deep Learning, Deep Neural Decision Forest, COVID-19, Polymerase Chain Reaction, RT-PCR. 1. Introduction COVID-19 was first observed as a deadly illness in the Wuhan region of China in 2019. It was highly contagious and spread rapidly through direct contact with an infected individual [1].

AI diagnostics startup MediCircle Health has recently introduced in India a rapid spectrometry-based test that employs machine learning and artificial intelligence to detect COVID-19. Spectral Instant Test (SpectraLIT) is a point-of-care diagnostic platform that performs spectral analysis to accurately and instantly determine if a spectral pattern of a virus from a nasal or mouthwash sample resembles SARS-CoV-2, the virus causing COVID-19. The test can deliver results "within seconds of its use", according to a press release by MediCircle. The company shared that the portable solution can be used for entry screening at various airports, malls, schools and other venues. It can also potentially enable secure and real-time reporting to health and other designated authorities.

Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations. We develop a scalable approach for determining the viral status of pooled patient samples. Our approach converts group testing to a linear inverse problem, where false positives and negatives are interpreted as generated by a noisy communication channel, and a message passing algorithm estimates the illness status of patients. Numerical results reveal that our approach estimates patient illness using fewer pooled measurements than existing noisy group testing algorithms. Our approach can easily be extended to various applications, including where false negatives must be minimized. Finally, in a Utopian world we would have collaborated with RT-PCR experts; it is difficult to form such connections during a pandemic. We welcome new collaborators to reach out and help improve this work!