Metabolism is essential to all living organisms, and modelling the chemical reactions that sustain life is no easy task. The complex process of an organism metabolizing nutrients can be modelled by a set of mathematical equations with parameters specific to each organism. The parameters one would measure for a human would be different from those of a mouse, bacteria, yeast, or any living organism of study. If we had access to these parameters for a given living organism, then its corresponding model would be complete, it would match real-world observation, and in silico studies would be possible for better design of in vitro and in vivo studies. On a practical level, however, determining those parameters is a complicated matter, due to the lack of experimental data.

As audience surrogate and everyman, Ethan Winters is not an interesting or wise character. But "Village" eventually turns him into a sympathetic one, painting him as a hapless, entangled victim. By the end of the game, Ethan Winters is no longer the dogged, serious and scared hero of "Biohazard." Unlike the lonely "Biohazard," "Village" ends with a muddy conspiracy and muddier motivations, and at a scale we haven't seen since the loud, ridiculous "Resident Evil 6," all the way back in 2012.