Feedforward network (FFN) layers account for a large fraction of parameters and nonlinear expressivity in Transformer-based large language models (LLMs). Despite the evolution from ReLU and GELU to gated variants such as SwiGLU, most FFN designs still use a single fixed activation function, applying the same nonlinear transformation to all tokens. In this work, we propose Mixture of Activations (MoA), a token-adaptive FFN design that mixes a dictionary of activation functions using lightweight input-dependent gates while sharing the same linear projections. As an input-independent counterpart, we also introduce learnable activations (LA), which form linear combinations of activation functions for both ReLU-type and SwiGLU-type FFNs. Theoretically, we establish strict finite-width expressive separations among fixed-activation FFNs, LA, and MoA: LA strictly contains fixed-activation FFNs, while MoA strictly contains LA, with the additional expressivity arising from input-dependent nonlinear hybridization. Empirically, we evaluate MoA through extensive pre-training experiments on dense and MoE language models ranging from 0.12B to 2B parameters under different token budgets, optimizers, and learning rate schedules. MoA consistently achieves lower terminal loss and exhibits more favorable scaling behavior than well-tuned baselines, with minimal parameter and computational overhead. These results suggest that token-adaptive activation mixing is a simple and effective mechanism for improving FFN expressivity in LLMs.

Role-playing agents (RPAs) must simultaneously master many conflicting skills -- following multi-turn instructions, exhibiting domain knowledge, and adopting a consistent linguistic style. Existing work either relies on supervised fine-tuning (SFT) that over-fits surface cues and yields low diversity, or applies reinforcement learning (RL) that fails to learn multiple dimensions for comprehensive RPA optimization. We present MOA (Multi-Objective Alignment), a reinforcement-learning framework that enables multi-dimensional, fine-grained rubric optimization for general RPAs. MOA introduces a novel multi-objective optimization strategy that trains simultaneously on multiple fine-grained rubrics to boost optimization performance. Besides, to address the issues of model output diversity and quality, we have also employed thought-augmented rollout with off-policy guidance. Extensive experiments on challenging benchmarks such as PersonaGym and RoleMRC show that MOA enables an 8B model to match or even outperform strong baselines such as GPT-4o and Claude across numerous dimensions. This demonstrates the great potential of MOA in building RPAs that can simultaneously meet the demands of role knowledge, persona style, diverse scenarios, and complex multi-turn conversations.

Two scientific fields showing increasing interest in pre-trained large language models (LLMs) are drug development / repurposing, and personalized medicine. For both, LLMs have to demonstrate factual knowledge as well as a deep understanding of drug mechanisms, so they can recall and reason about relevant knowledge in novel situations. Drug mechanisms of action are described as a series of interactions between biomedical entities, which interlink into one or more chains directed from the drug to the targeted disease. Composing the effects of the interactions in a candidate chain leads to an inference about whether the drug might be useful or not for that disease. We introduce a dataset that evaluates LLMs on both factual knowledge of known mechanisms, and their ability to reason about them under novel situations, presented as counterfactuals that the models are unlikely to have seen during training. Using this dataset, we show that o4-mini outperforms the 4o, o3, and o3-mini models from OpenAI, and the recent small Qwen3-4B-thinking model closely matches o4-mini's performance, even outperforming it in some cases. We demonstrate that the open world setting for reasoning tasks, which requires the model to recall relevant knowledge, is more challenging than the closed world setting where the needed factual knowledge is provided. We also show that counterfactuals affecting internal links in the reasoning chain present a much harder task than those affecting a link from the drug mentioned in the prompt.

Large-scale scientific datasets -- spanning health biobanks, cell atlases, Earth reanalyses, and more -- create opportunities for exploratory discovery unconstrained by specific research questions. We term this process hypothesis hunting: the cumulative search for insight through sustained exploration across vast and complex hypothesis spaces. To support it, we introduce AScience, a framework modeling discovery as the interaction of agents, networks, and evaluation norms, and implement it as ASCollab, a distributed system of LLM-based research agents with heterogeneous behaviors. These agents self-organize into evolving networks, continually producing and peer-reviewing findings under shared standards of evaluation. Experiments show that such social dynamics enable the accumulation of expert-rated results along the diversity-quality-novelty frontier, including rediscoveries of established biomarkers, extensions of known pathways, and proposals of new therapeutic targets. While wet-lab validation remains indispensable, our experiments on cancer cohorts demonstrate that socially structured, agentic networks can sustain exploratory hypothesis hunting at scale.

Emotion Recognition in Conversations (ERC) is hard because discriminative evidence is sparse, localized, and often asynchronous across modalities. We center ERC on emotion hotspots and present a unified model that detects per-utterance hotspots in text, audio, and video, fuses them with global features via Hotspot-Gated Fusion, and aligns modalities using a routed Mixture-of-Aligners; a cross-modal graph encodes conversational structure. This design focuses modeling on salient spans, mitigates misalignment, and preserves context. Experiments on standard ERC benchmarks show consistent gains over strong baselines, with ablations confirming the contributions of HGF and MoA. Our results point to a hotspot-centric view that can inform future multimodal learning, offering a new perspective on modality fusion in ERC.

Recent advancements in Large Language Models (LLMs) for code optimization have enabled industrial platforms to automate software performance engineering at unprecedented scale and speed. Yet, organizations in regulated industries face strict constraints on which LLMs they can use - many cannot utilize commercial models due to data privacy regulations and compliance requirements, creating a significant challenge for achieving high-quality code optimization while maintaining cost-effectiveness. We address this by implementing a Mixture-of-Agents (MoA) approach that directly synthesizes code from multiple specialized LLMs, comparing it against TurinTech AI's vanilla Genetic Algorithm (GA)-based ensemble system and individual LLM optimizers using real-world industrial codebases. Our key contributions include: (1) First MoA application to industrial code optimization using real-world codebases; (2) Empirical evidence that MoA excels with open-source models, achieving 14.3% to 22.2% cost savings and 28.6% to 32.2% faster optimization times for regulated environments; (3) Deployment guidelines demonstrating GA's advantage with commercial models while both ensembles outperform individual LLMs; and (4) Real-world validation across 50 code snippets and seven LLM combinations, generating over 8,700 variants, addresses gaps in industrial LLM ensemble evaluation. This provides actionable guidance for organizations balancing regulatory compliance with optimization performance in production environments.

Building helpful and harmless large language models (LLMs) requires effective model alignment approach based on human instructions and feedback, which necessitates high-quality human-labeled data. Constructing such datasets is often expensive and hard to scale, and may face potential limitations on diversity and generalization. To address these challenges, we introduce Mixture of Agents Alignment (MoAA), that leverages the collective strengths of various language models to provide high-quality data for model alignment. By employing MoAA, we enhance both supervised fine-tuning and preference optimization, leading to improved performance compared to using a single model alone to generate alignment data (e.g. using GPT-4o alone). Evaluation results show that our approach can improve win rate of LLaMA-3.1-8B-Instruct from 19.5 to 48.3 on Arena-Hard and from 22.33 to 57.23 on AlpacaEval2, highlighting a promising direction for model alignment through this new scalable and diverse synthetic data recipe. Furthermore, we demonstrate that MoAA enables a self-improvement pipeline, where models finetuned on MoA-generated data surpass their own initial capabilities, providing evidence that our approach can push the frontier of open-source LLMs without reliance on stronger external supervision. Data and code will be released.

Despite the transformative impact of Artificial Intelligence (AI) across various sectors, cyber security continues to rely on traditional static and dynamic analysis tools, hampered by high false positive rates and superficial code comprehension. While generative AI offers promising automation capabilities for software development, leveraging Large Language Models (LLMs) for vulnerability detection presents unique challenges. This paper explores the potential and limitations of LLMs in identifying vulnerabilities, acknowledging inherent weaknesses such as hallucinations, limited context length, and knowledge cut-offs. Previous attempts employing machine learning models for vulnerability detection have proven ineffective due to limited real-world applicability, feature engineering challenges, lack of contextual understanding, and the complexities of training models to keep pace with the evolving threat landscape. Therefore, we propose a robust AI-driven approach focused on mitigating these limitations and ensuring the quality and reliability of LLM based vulnerability detection. Through innovative methodologies combining Retrieval-Augmented Generation (RAG) and Mixtureof-Agents (MoA), this research seeks to leverage the strengths of LLMs while addressing their weaknesses, ultimately paving the way for dependable and efficient AI-powered solutions in securing the ever-evolving software landscape.

Mixture of large language model (LLMs) Agents (MoA) architectures achieve state-of-the-art performance on prominent benchmarks like AlpacaEval 2.0 by leveraging the collaboration of multiple LLMs at inference time. Despite these successes, an evaluation of the safety and reliability of MoA is missing. We present the first comprehensive study of MoA's robustness against deceptive LLM agents that deliberately provide misleading responses. We examine factors like the propagation of deceptive information, model size, and information availability, and uncover critical vulnerabilities. On AlpacaEval 2.0, the popular LLaMA 3.1-70B model achieves a length-controlled Win Rate (LC WR) of 49.2% when coupled with 3-layer MoA (6 LLM agents). However, we demonstrate that introducing only a $\textit{single}$ carefully-instructed deceptive agent into the MoA can reduce performance to 37.9%, effectively nullifying all MoA gains. On QuALITY, a multiple-choice comprehension task, the impact is also severe, with accuracy plummeting by a staggering 48.5%. Inspired in part by the historical Doge of Venice voting process, designed to minimize influence and deception, we propose a range of unsupervised defense mechanisms that recover most of the lost performance.

Mixture-of-Agents (MoA) has recently been proposed as a method to enhance performance of large language models (LLMs), enabling multiple individual LLMs to work together for collaborative inference. This collaborative approach results in improved responses to user prompts compared to relying on a single LLM. In this paper, we consider such an MoA architecture in a distributed setting, where LLMs operate on individual edge devices, each uniquely associated with a user and equipped with its own distributed computing power. These devices exchange information using decentralized gossip algorithms, allowing different device nodes to talk without the supervision of a centralized server. In the considered setup, different users have their own LLM models to address user prompts. Additionally, the devices gossip either their own user-specific prompts or augmented prompts to generate more refined answers to certain queries. User prompts are temporarily stored in the device queues when their corresponding LLMs are busy. Given the memory limitations of edge devices, it is crucial to ensure that the average queue sizes in the system remain bounded. In this paper, we address this by theoretically calculating the queuing stability conditions for the device queues under reasonable assumptions, which we validate experimentally as well. Further, we demonstrate through experiments, leveraging open-source LLMs for the implementation of distributed MoA, that certain MoA configurations produce higher-quality responses compared to others, as evaluated on AlpacaEval 2.0 benchmark. The implementation is available at: https://github.com/purbeshmitra/distributed_moa.