However, REs purely rely on expert knowledge and cannot utilize labeled data for better accuracy. Today, neural networks (NNs) have shown superior accuracy and flexibility, thanks to their ability to learn from rich labeled data. Nevertheless, NNs are often incompetent in cold-start scenarios and too complex for deployment on network devices. In this paper, we propose Metis, a general framework that converts REs to network device affordable models for superior accuracy and throughput by taking advantage of REs' expert knowledge and NNs' learning ability. In Metis, we convert REs to byte-level recurrent neural networks (BRNNs) without training.

Building a generalist robot that can perceive, reason, and act across diverse tasks remains an open challenge, especially for dexterous manipulation. A major bottleneck lies in the scarcity of large-scale, action-annotated data for dexterous skills, as teleoperation is difficult and costly. Human data, with its vast scale and diverse manipulation behaviors, provides rich priors for learning robotic actions. While prior works have explored leveraging human demonstrations, they are often constrained by limited scenarios and a large visual gap between human and robots. To eliminate these limitations, we propose METIS, a vision-language-action (VLA) model for dexterous manipulation pretrained on multi-source egocentric datasets. We first construct EgoAtlas, which integrates large-scale human and robotic data from multiple sources, all unified under a consistent action space. We further extract motion-aware dynamics, a compact and discretized motion representation, which provides efficient and expressive supervision for VLA training. Built upon them, METIS integrates reasoning and acting into a unified framework, enabling effective deployment to downstream dexterous manipulation tasks. Our method demonstrates exceptional dexterous manipulation capabilities, achieving highest average success rate in six real-world tasks. Experimental results also highlight the superior generalization and robustness to out-of-distribution scenarios. These findings emphasize METIS as a promising step toward a generalist model for dexterous manipulation.

Nevertheless, NNs are often incompetent in cold-start scenarios and too complex for deployment on network devices.

We study distributed training of Graph Neural Networks (GNNs) on billion-scale graphs that are partitioned across machines. Efficient training in this setting relies on min-edge-cut partitioning algorithms, which minimize cross-machine communication due to GNN neighborhood sampling. Yet, min-edge-cut partitioning over large graphs remains a challenge: State-of-the-art (SoTA) offline methods (e.g., METIS) are effective, but they require orders of magnitude more memory and runtime than GNN training itself, while computationally efficient algorithms (e.g., streaming greedy approaches) suffer from increased edge cuts. Thus, in this work we introduce Armada, a new end-to-end system for distributed GNN training whose key contribution is GREM, a novel min-edge-cut partitioning algorithm that can efficiently scale to large graphs. GREM builds on streaming greedy approaches with one key addition: prior vertex assignments are continuously refined during streaming, rather than frozen after an initial greedy selection. Our theoretical analysis and experimental results show that this refinement is critical to minimizing edge cuts and enables GREM to reach partition quality comparable to METIS but with 8-65x less memory and 8-46x faster. Given a partitioned graph, Armada leverages a new disaggregated architecture for distributed GNN training to further improve efficiency; we find that on common cloud machines, even with zero communication, GNN neighborhood sampling and feature loading bottleneck training. Disaggregation allows Armada to independently allocate resources for these operations and ensure that expensive GPUs remain saturated with computation. We evaluate Armada against SoTA systems for distributed GNN training and find that the disaggregated architecture leads to runtime improvements up to 4.5x and cost reductions up to 3.1x.

We introduce Metis, a foundation model for unified speech generation. Unlike previous task-specific or multi-task models, Metis follows a pre-training and fine-tuning paradigm. It is pre-trained on large-scale unlabeled speech data using masked generative modeling and then fine-tuned to adapt to diverse speech generation tasks. Specifically, 1) Metis utilizes two discrete speech representations: SSL tokens derived from speech self-supervised learning (SSL) features, and acoustic tokens directly quantized from waveforms. 2) Metis performs masked generative pre-training on SSL tokens, utilizing 300K hours of diverse speech data, without any additional condition. 3) Through fine-tuning with task-specific conditions, Metis achieves efficient adaptation to various speech generation tasks while supporting multimodal input, even when using limited data and trainable parameters. Experiments demonstrate that Metis can serve as a foundation model for unified speech generation: Metis outperforms state-of-the-art task-specific or multi-task systems across five speech generation tasks, including zero-shot text-to-speech, voice conversion, target speaker extraction, speech enhancement, and lip-to-speech, even with fewer than 20M trainable parameters or 300 times less training data. Audio samples are are available at https://metis-demo.github.io/.

However, REs purely rely on expert knowledge and cannot utilize labeled data for better accuracy. Today, neural networks (NNs) have shown superior accuracy and flexibility, thanks to their ability to learn from rich labeled data. Nevertheless, NNs are often incompetent in cold-start scenarios and too complex for deployment on network devices. In this paper, we propose Metis, a general framework that converts REs to network device affordable models for superior accuracy and throughput by taking advantage of REs' expert knowledge and NNs' learning ability. In Metis, we convert REs to byte-level recurrent neural networks (BRNNs) without training.

As humanity prepares for new missions to the Moon and Mars, astronauts will need to operate with greater autonomy, given the communication delays that make real-time support from Earth difficult. For instance, messages between Mars and Earth can take up to 24 minutes, making quick responses impossible. This limitation poses a challenge for astronauts who must rely on in-situ tools to access the large volume of data from spacecraft sensors, rovers, and satellites, data that is often fragmented and difficult to use. To bridge this gap, systems like the Mars Exploration Telemetry-Driven Information System (METIS) are being developed. METIS is an AI assistant designed to handle routine tasks, monitor spacecraft systems, and detect anomalies, all while reducing the reliance on mission control. Current Generative Pretrained Transformer (GPT) Models, while powerful, struggle in safety-critical environments. They can generate plausible but incorrect responses, a phenomenon known as "hallucination," which could endanger astronauts. To overcome these limitations, this paper proposes enhancing systems like METIS by integrating GPTs, Retrieval-Augmented Generation (RAG), Knowledge Graphs (KGs), and Augmented Reality (AR). The idea is to allow astronauts to interact with their data more intuitively, using natural language queries and visualizing real-time information through AR. KGs will be used to easily access live telemetry and multimodal data, ensuring that astronauts have the right information at the right time. By combining AI, KGs, and AR, this new system will empower astronauts to work more autonomously, safely, and efficiently during future space missions.

In the area of large-scale training of graph embeddings, effective training frameworks and partitioning methods are critical for handling large networks. However, they face two major challenges: 1) existing synchronized distributed frameworks require continuous communication to access information from other machines, and 2) the inability of current partitioning methods to ensure that subgraphs remain connected components without isolated nodes, which is essential for effective training of GNNs since training relies on information aggregation from neighboring nodes. To address these issues, we introduce a novel partitioning method, named Leiden-Fusion, designed for large-scale training of graphs with minimal communication. Our method extends the Leiden community detection algorithm with a greedy algorithm that merges the smallest communities with highly connected neighboring communities. Our method guarantees that, for an initially connected graph, each partition is a densely connected subgraph with no isolated nodes. After obtaining the partitions, we train a GNN for each partition independently, and finally integrate all embeddings for node classification tasks, which significantly reduces the need for network communication and enhances the efficiency of distributed graph training. We demonstrate the effectiveness of our method through extensive evaluations on several benchmark datasets, achieving high efficiency while preserving the quality of the graph embeddings for node classification tasks.

In this study, we generate and maintain a database of 10 million virtual lipids through METiS's in-house de novo lipid generation algorithms and lipid virtual screening techniques. These virtual lipids serve as a corpus for pre-training, lipid representation learning, and downstream task knowledge transfer, culminating in state-of-the-art LNP property prediction performance. We propose LipidBERT, a BERT-like model pre-trained with the Masked Language Model (MLM) and various secondary tasks. Additionally, we compare the performance of embeddings generated by LipidBERT and PhatGPT, our GPT-like lipid generation model, on downstream tasks. The proposed bilingual LipidBERT model operates in two languages: the language of ionizable lipid pre-training, using in-house dry-lab lipid structures, and the language of LNP fine-tuning, utilizing in-house LNP wet-lab data. This dual capability positions LipidBERT as a key AI-based filter for future screening tasks, including new versions of METiS de novo lipid libraries and, more importantly, candidates for in vivo testing for orgran-targeting LNPs. To the best of our knowledge, this is the first successful demonstration of the capability of a pre-trained language model on virtual lipids and its effectiveness in downstream tasks using web-lab data. This work showcases the clever utilization of METiS's in-house de novo lipid library as well as the power of dry-wet lab integration.