Clinical decision support systems (CDSS) are used to improve clinical and service outcomes, yet evidence from low- and middle-income countries (LMICs) is dispersed. This protocol outlines methods to quantify the impact of CDSS on patient and healthcare delivery outcomes in LMICs. We will include comparative quantitative designs (randomized trials, controlled before-after, interrupted time series, comparative cohorts) evaluating CDSS in World Bank-defined LMICs. Standalone qualitative studies are excluded; mixed-methods studies are eligible only if they report comparative quantitative outcomes, for which we will extract the quantitative component. Searches (from inception to 30 September 2024) will cover MEDLINE, Embase, CINAHL, CENTRAL, Web of Science, Global Health, Scopus, IEEE Xplore, LILACS, African Index Medicus, and IndMED, plus grey sources. Screening and extraction will be performed in duplicate. Risk of bias will be assessed with RoB 2 (randomized trials) and ROBINS-I (non-randomized). Random-effects meta-analysis will be performed where outcomes are conceptually or statistically comparable; otherwise, a structured narrative synthesis will be presented. Heterogeneity will be explored using relative and absolute metrics and a priori subgroups or meta-regression (condition area, care level, CDSS type, readiness proxies, study design).

The deployment of large language models (LLMs) in healthcare has demonstrated substantial potential for enhancing clinical decision-making, administrative efficiency, and patient outcomes. However, the underrepresentation of diverse groups in the development and application of these models can perpetuate biases, leading to inequitable healthcare delivery. This paper presents a comprehensive scientometric analysis of LLM research for healthcare, including data from January 1, 2021, to June 16, 2024. By analyzing metadata from PubMed and Dimensions, including author affiliations, countries, and funding sources, we assess the diversity of contributors to LLM research. Our findings highlight significant gender and geographic disparities, with a predominance of male authors and contributions primarily from high-income countries (HICs). We introduce a novel journal diversity index based on Gini impurity to measure the inclusiveness of scientific publications. Our results underscore the necessity for greater representation in order to ensure the equitable application of LLMs in healthcare. We propose actionable strategies to enhance diversity and inclusivity in artificial intelligence research, with the ultimate goal of fostering a more inclusive and equitable future in healthcare innovation.

Addressing the imminent shortfall of 10 million health workers by 2030, predominantly in Low- and Middle-Income Countries (LMICs), this paper introduces an innovative approach that harnesses the power of Large Language Models (LLMs) integrated with machine translation models. This solution is engineered to meet the unique needs of Community Health Workers (CHWs), overcoming language barriers, cultural sensitivities, and the limited availability of medical dialog datasets. I have crafted a model that not only boasts superior translation capabilities but also undergoes rigorous fine-tuning on open-source datasets to ensure medical accuracy and is equipped with comprehensive safety features to counteract the risks of misinformation. Featuring a modular design, this approach is specifically structured for swift adaptation across various linguistic and cultural contexts, utilizing open-source components to significantly reduce healthcare operational costs. This strategic innovation markedly improves the accessibility and quality of healthcare services by providing CHWs with contextually appropriate medical knowledge and diagnostic tools. This paper highlights the transformative impact of this context-aware LLM, underscoring its crucial role in addressing the global healthcare workforce deficit and propelling forward healthcare outcomes in LMICs.

This paper presents emerging evidence of using generative large language models (i.e., GPT-4) to reliably evaluate short-answer reading comprehension questions. Specifically, we explore how various configurations of generative (LLMs) are able to evaluate student responses from a new dataset, drawn from a battery of reading assessments conducted with over 150 students in Ghana. As this dataset is novel and hence not used in training runs of GPT, it offers an opportunity to test for domain shift and evaluate the generalizability of generative LLMs, which are predominantly designed and trained on data from high-income North American countries. We found that GPT-4, with minimal prompt engineering performed extremely well on evaluating the novel dataset (Quadratic Weighted Kappa 0.923, F1 0.88), substantially outperforming transfer-learning based approaches, and even exceeding expert human raters (Quadratic Weighted Kappa 0.915, F1 0.87). To the best of our knowledge, our work is the first to empirically evaluate the performance of generative LLMs on short-answer reading comprehension questions, using real student data, and suggests that generative LLMs have the potential to reliably evaluate foundational literacy. Currently the assessment of formative literacy and numeracy is infrequent in many low and middle-income countries (LMICs) due to the cost and operational complexities of conducting them at scale. Automating the grading process for reading assessment could enable wider usage, and in turn improve decision-making regarding curricula, school management, and teaching practice at the classroom level. Importantly, in contrast transfer learning based approaches, generative LLMs generalize well and the technical barriers to their use are low, making them more feasible to implement and scale in lower resource educational contexts.

Abstract: We present a Machine Learning (ML) study case to illustrate the challenges of clinical translation for a real-time AI-empowered echocardiography system with data of ICU patients in LMICs. Such ML case study includes data preparation, curation and labelling from 2D Ultrasound videos of 31 ICU patients in LMICs and model selection, validation and deployment of three thinner neural networks to classify apical four-chamber view. Results of the ML heuristics showed the promising implementation, validation and application of thinner networks to classify 4CV with limited datasets. We conclude this work mentioning the need for (a) datasets to improve diversity of demographics, diseases, and (b) the need of further investigations of thinner models to be run and implemented in low-cost hardware to be clinically translated in the ICU in LMICs. Abstract: The ability to jointly learn from multiple modalities, such as text, audio, and visual data, is a defining feature of intelligent systems.

Udunna C. Anazodo, PhD, is an assistant professor of neurology and neurosurgery at the Montreal Neurological Institute at McGill University. She is the founder and chair of the Consortium for Advancement of MRI Education and Research in Africa (CAMERA) and is currently leading efforts to create the Africa Neuroimaging Archive (AfNiA). Her research interests include diagnostic image analysis using artificial intelligence methods to enable quantitative PET and MRI for population neuroscience and global health. Maruf Adewole, MSc, is a medical physicist. He holds a bachelor's degree in physics and master's degree in medical physics from the Federal University of Technology Akure and University of Lagos, Nigeria, respectively.

Ranveer Chandra is the managing director of Research for Industry and leads Networking Research at Microsoft Research in Redmond, WA, USA. His research has shipped in multiple Microsoft products, including Xbox, Azure, and Windows. Stewart Collis is senior program officer for Digital Agriculture Solutions at the Bill and Melinda Gates Foundation where he focuses on digital farmer services, smart farming, and digital support systems for small-scale crop and livestock producers in low- and middle-income countries.

Within the national innovation system literature, empirical analyses are severely lacking for developing economies. Particularly, the low- and middle-income countries (LMICs) eligible for the World Bank's International Development Association (IDA) support, are rarely part of any empirical discourse on growth, development, and innovation. One major issue hindering panel analyses in LMICs, and thus them being subject to any empirical discussion, is the lack of complete data availability. This work offers a new complete panel dataset with no missing values for LMICs eligible for IDA's support. I use a standard, widely respected multiple imputation technique (specifically, Predictive Mean Matching) developed by Rubin (1987). This technique respects the structure of multivariate continuous panel data at the country level. I employ this technique to create a large dataset consisting of many variables drawn from publicly available established sources. These variables, in turn, capture six crucial country-level capacities: technological capacity, financial capacity, human capital capacity, infrastructural capacity, public policy capacity, and social capacity. Such capacities are part and parcel of the National Absorptive Capacity Systems (NACS). The dataset (MSK dataset) thus produced contains data on 47 variables for 82 LMICs between 2005 and 2019. The dataset has passed a quality and reliability check and can thus be used for comparative analyses of national absorptive capacities and development, transition, and convergence analyses among LMICs.

In the past 10 years, hundreds of projects have applied artificial intelligence (AI) to creating social good. The right tool applied to an appropriate problem has the potential to drastically improve millions of lives through better service delivery and better-informed policy design. But what kind of investments do AI solutions need to be successful, and which applications have the most potential for social impact? AI excels at helping humans harness large-scale or complex data to predict, categorize, or optimize at a scale and speed beyond human ability. We believe that more targeted, sustained investments in AI for social impact (sometimes called "AI for good")--rather than multiple, short-term grants across a variety of areas--are important for two reasons.

Around the world, artificial intelligence (AI) is automating functions and making new services possible with breakthroughs in low-cost computing power, cloud computing services, growth in big data and advancements in machine learning and related processes. This webinar discussed the current use of AI in low- and middle-income countries (LMICs), along with trends and challenges in business models, barriers to innovation and AI's ethical and responsible use towards achieving the sustainable development goals. This study examines the current use of AI in low- and middle-income countries (LMICs) across Sub-Saharan Africa, North Africa and South and Southeast Asia. The report mapped a sample of 450 start-ups by sector in alignment with the UN Sustainable ...