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Reid Hoffman Thinks Doctors Should Ask AI for a Second Opinion
The LinkedIn cofounder now has an AI drug discovery startup--and thinks not asking chatbots for medical advice is "bordering on committing malpractice." Following a three-decade career at the helm of some of Silicon Valley's most powerful companies--cofounding LinkedIn and sitting on the boards of PayPal and OpenAI-- Reid Hoffman recently turned his attention to health care. Hoffman's startup, Manas AI, is building an AI engine that aims to fast-track the traditionally slow process of drug discovery for various cancers. Inspired by a dinner with renowned cancer physician Siddhartha Mukherjee, the company's cofounder and CEO, its mission statement is to "shift drug discovery from a decade-long process to one that takes a few years." But Hoffman's enthusiasm for generative AI, in particular, stretches far beyond novel drug targets and small molecules.
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Similarly, self-supervised representation learning (SSL) is rapidly replacing supervised learning as the de-facto pretraining strategy for deep networks, due to improved scalability (unlabeled data is easier to collect) and generality (domain-specific SSL is often preferable to one-fits-all ImageNet pretraining [16,17]).
America Isn't Ready for What AI Will Do to Jobs
This story appears in the March 2026 print edition. While some stories from this issue are not yet available to read online, you can explore more from the magazine . Get our editors' guide to what matters in the world, delivered to your inbox every weekday. America Isn't Ready for What AI Will Do to Jobs Does anyone have a plan for what happens next? In 1869, a group of Massachusetts reformers persuaded the state to try a simple idea: counting. The Second Industrial Revolution was belching its way through New England, teaching mill and factory owners a lesson most M.B.A. students now learn in their first semester: that efficiency gains tend to come from somewhere, and that somewhere is usually somebody else. They were operating at speeds that the human body--an elegant piece of engineering designed over millions of years for entirely different purposes--simply wasn't built to match. The owners knew this, just as they knew that there's a limit to how much misery people are willing to tolerate before they start setting fire to things. Still, the machines pressed on. Check out more from this issue and find your next story to read. So Massachusetts created the nation's first Bureau of Statistics of Labor, hoping that data might accomplish what conscience could not. By measuring work hours, conditions, wages, and what economists now call "negative externalities" but were then called "children's arms torn off," policy makers figured they might be able to produce reasonably fair outcomes for everyone. A few years later, with federal troops shooting at striking railroad workers and wealthy citizens funding private armories--leading indicators that things in your society aren't going great--Congress decided that this idea might be worth trying at scale and created the Bureau of Labor Statistics. Measurement doesn't abolish injustice; it rarely even settles arguments. But the act of counting--of trying to see clearly, of committing the government to a shared set of facts--signals an intention to be fair, or at least to be caught trying. It's one way a republic earns the right to be believed in. The BLS remains a small miracle of civilization.