fdd
Freeze, Diffuse, Decode: Geometry-Aware Adaptation of Pretrained Transformer Embeddings for Antimicrobial Peptide Design
Gawade, Pankhil, Izdebski, Adam, Lizotte, Myriam, Moon, Kevin R., Rhodes, Jake S., Wolf, Guy, Szczurek, Ewa
Pretrained transformers provide rich, general-purpose embeddings, which are transferred to downstream tasks. However, current transfer strategies: fine-tuning and probing, either distort the pretrained geometric structure of the embeddings or lack sufficient expressivity to capture task-relevant signals. These issues become even more pronounced when supervised data are scarce. Here, we introduce Freeze, Diffuse, Decode (FDD), a novel diffusion-based framework that adapts pre-trained embeddings to downstream tasks while preserving their underlying geometric structure. FDD propagates supervised signal along the intrinsic manifold of frozen embeddings, enabling a geometry-aware adaptation of the embedding space. Applied to antimicrobial peptide design, FDD yields low-dimensional, predictive, and interpretable representations that support property prediction, retrieval, and latent-space interpolation.
- North America > United States > Minnesota > Hennepin County > Minneapolis (0.14)
- Europe > Germany > Bavaria > Upper Bavaria > Munich (0.05)
- Europe > Poland > Masovia Province > Warsaw (0.04)
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CSI-4CAST: A Hybrid Deep Learning Model for CSI Prediction with Comprehensive Robustness and Generalization Testing
Cheng, Sikai, Zandehshahvar, Reza, Zhao, Haoruo, Garcia-Ulloa, Daniel A., Villena-Rodriguez, Alejandro, Manchón, Carles Navarro, Van Hentenryck, Pascal
Channel state information (CSI) prediction is a promising strategy for ensuring reliable and efficient operation of massive multiple-input multiple-output (mMIMO) systems by providing timely downlink (DL) CSI. While deep learning-based methods have advanced beyond conventional model-driven and statistical approaches, they remain limited in robustness to practical non-Gaussian noise, generalization across diverse channel conditions, and computational efficiency. This paper introduces CSI-4CAST, a hybrid deep learning architecture that integrates 4 key components, i.e., Convolutional neural network residuals, Adaptive correction layers, ShuffleNet blocks, and Transformers, to efficiently capture both local and long-range dependencies in CSI prediction. To enable rigorous evaluation, this work further presents a comprehensive benchmark, CSI-RRG for Regular, Robustness and Generalization testing, which includes more than 300,000 samples across 3,060 realistic scenarios for both TDD and FDD systems. The dataset spans multiple channel models, a wide range of delay spreads and user velocities, and diverse noise types and intensity degrees. Experimental results show that CSI-4CAST achieves superior prediction accuracy with substantially lower computational cost, outperforming baselines in 88.9% of TDD scenarios and 43.8% of FDD scenario, the best performance among all evaluated models, while reducing FLOPs by 5x and 3x compared to LLM4CP, the strongest baseline. In addition, evaluation over CSI-RRG provides valuable insights into how different channel factors affect the performance and generalization capability of deep learning models. Both the dataset (https://huggingface.co/CSI-4CAST) and evaluation protocols (https://github.com/AI4OPT/CSI-4CAST) are publicly released to establish a standardized benchmark and to encourage further research on robust and efficient CSI prediction.
- North America > United States > Georgia > Fulton County > Atlanta (0.04)
- Europe > United Kingdom > England > Cambridgeshire > Cambridge (0.04)
- Asia > China (0.04)
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s Lemma shows our model can be used to construct a broad range of 3
We would like to thank all the reviewers for their thoughtful comments. We will respond to each reviewer's questions Itô diffusion processes with tractable finite-dimensional distributions (FDD). To show the correctness of Eqs. Since our experiments focus on low-dimensional data, the time cost is not a major bottleneck. We agree with the reviewer's comment on Eq.(12):
Assumption-Based Argumentation for Communicating Agents
Hussain, Adil (Imperial College London) | Toni, Francesca (Imperial College London)
Assumption-Based Argumentation (ABA), and to a large extent argumentation in general, up to now has been considered in a single-agent setting. ABA, in particular, is such that an agent engages in a dispute (dialectic proof procedure) with itself (an imaginary opponent) to decide whether a claim is acceptable according to some acceptability criteria. We present in this paper a generalised proof procedure for the admissibility semantics of ABA, which is still a dispute by an agent with itself but such that the outcome can be readily communicated to other agents. This is important for applications in multi-agent systems wherein agents may differ in the knowledge they have and may need to communicate their arguments between one another to convince each other of the acceptability or not of a given claim.