The Circle of Willis (CoW), vital for ensuring consistent blood flow to the brain, is closely linked to ischemic stroke. Accurate assessment of the CoW is important for identifying individuals at risk and guiding appropriate clinical management. Among existing imaging methods, Transcranial Color-coded Doppler (TCCD) offers unique advantages due to its radiation-free nature, affordability, and accessibility. However, reliable TCCD assessments depend heavily on operator expertise for identifying anatomical landmarks and performing accurate angle correction, which limits its widespread adoption. To address this challenge, we propose an AI-powered, real-time CoW auto-segmentation system capable of efficiently capturing cerebral arteries. No prior studies have explored AI-driven cerebrovascular segmentation using TCCD. In this work, we introduce a novel Attention-Augmented Wavelet YOLO (AAW-YOLO) network tailored for TCCD data, designed to provide real-time guidance for brain vessel segmentation in the CoW. We prospectively collected TCCD data comprising 738 annotated frames and 3,419 labeled artery instances to establish a high-quality dataset for model training and evaluation. The proposed AAW-YOLO demonstrated strong performance in segmenting both ipsilateral and contralateral CoW vessels, achieving an average Dice score of 0.901, IoU of 0.823, precision of 0.882, recall of 0.926, and mAP of 0.953, with a per-frame inference speed of 14.199 ms. This system offers a practical solution to reduce reliance on operator experience in TCCD-based cerebrovascular screening, with potential applications in routine clinical workflows and resource-constrained settings. Future research will explore bilateral modeling and larger-scale validation.

We introduce UniRST, the first unified RST-style discourse parser capable of handling 18 treebanks in 11 languages without modifying their relation inventories. To overcome inventory incompatibilities, we propose and evaluate two training strategies: Multi-Head, which assigns separate relation classification layer per inventory, and Masked-Union, which enables shared parameter training through selective label masking. We first benchmark monotreebank parsing with a simple yet effective augmentation technique for low-resource settings. We then train a unified model and show that (1) the parameter efficient Masked-Union approach is also the strongest, and (2) UniRST outperforms 16 of 18 mono-treebank baselines, demonstrating the advantages of a single-model, multilingual end-to-end discourse parsing across diverse resources.

This paper presents DeDisCo, Georgetown University's entry in the DISRPT 2025 shared task on discourse relation classification. We test two approaches, using an mt5-based encoder and a decoder based approach using the openly available Qwen model. We also experiment on training with augmented dataset for low-resource languages using matched data translated automatically from English, as well as using some additional linguistic features inspired by entries in previous editions of the Shared Task. Our system achieves a macro-accuracy score of 71.28, and we provide some interpretation and error analysis for our results.

We consider a variant of the target defense problem in a planar conical environment where a single defender is tasked to capture a sequence of incoming attackers. The attackers' objective is to breach the target boundary without being captured by the defender. As soon as the current attacker breaches the target or gets captured by the defender, the next attacker appears at the boundary of the environment and moves radially toward the target with maximum speed. Therefore, the defender's final location at the end of the current game becomes its initial location for the next game. The attackers pick strategies that are advantageous for the current as well as for future engagements between the defender and the remaining attackers. The attackers have their own sensors with limited range, using which they can perfectly detect if the defender is within their sensing range. We derive equilibrium strategies for all the players to optimize the capture percentage using the notions of capture distribution. Finally, the theoretical results are verified through numerical examples using Monte Carlo type random trials of experiments.

Assessing the severity of rheumatoid arthritis (RA) using the Total Sharp/Van Der Heijde Score (TSS) is crucial, but manual scoring is often time-consuming and subjective. This study introduces an Automated Radiographic Sharp Scoring (ARTSS) framework that leverages deep learning to analyze full-hand X-ray images, aiming to reduce inter- and intra-observer variability. The research uniquely accommodates patients with joint disappearance and variable-length image sequences. We developed ARTSS using data from 970 patients, structured into four stages: I) Image pre-processing and re-orientation using ResNet50, II) Hand segmentation using UNet.3, III) Joint identification using YOLOv7, and IV) TSS prediction using models such as VGG16, VGG19, ResNet50, DenseNet201, EfficientNetB0, and Vision Transformer (ViT). We evaluated model performance with Intersection over Union (IoU), Mean Average Precision (MAP), mean absolute error (MAE), Root Mean Squared Error (RMSE), and Huber loss. The average TSS from two radiologists was used as the ground truth. Model training employed 3-fold cross-validation, with each fold consisting of 452 training and 227 validation samples, and external testing included 291 unseen subjects. Our joint identification model achieved 99% accuracy. The best-performing model, ViT, achieved a notably low Huber loss of 0.87 for TSS prediction. Our results demonstrate the potential of deep learning to automate RA scoring, which can significantly enhance clinical practice. Our approach addresses the challenge of joint disappearance and variable joint numbers, offers timesaving benefits, reduces inter- and intra-reader variability, improves radiologist accuracy, and aids rheumatologists in making more informed decisions.

Large language models (LLMs) learn non-trivial abstractions during pretraining, like detecting irregular plural noun subjects. However, it is not well understood when and how specific linguistic abilities emerge as traditional evaluation methods such as benchmarking fail to reveal how models acquire concepts and capabilities. To bridge this gap and better understand model training at the concept level, we use sparse crosscoders to discover and align features across model checkpoints. Using this approach, we track the evolution of linguistic features during pretraining. We train crosscoders between open-sourced checkpoint triplets with significant performance and representation shifts, and introduce a novel metric, Relative Indirect Effects (RelIE), to trace training stages at which individual features become causally important for task performance. We show that crosscoders can detect feature emergence, maintenance, and discontinuation during pretraining. Our approach is architecture-agnostic and scalable, offering a promising path toward more interpretable and fine-grained analysis of representation learning throughout pretraining.

Recent advances in large language models (LLMs) have shown impressive performance in mathematical reasoning and code generation. However, LLMs still struggle in the simulation domain, particularly in generating Simulink models, which are essential tools in engineering and scientific research. Our preliminary experiments indicate that LLM agents often fail to produce reliable and complete Simulink simulation code from text-only inputs, likely due to the lack of Simulink-specific data in their pretraining. To address this challenge, we propose SimuGen, a multimodal agent-based framework that automatically generates accurate Simulink simulation code by leveraging both the visual Simulink diagram and domain knowledge. SimuGen coordinates several specialized agents, including an investigator, unit test reviewer, code generator, executor, debug locator, and report writer, supported by a domain-specific knowledge base. This collaborative and modular design enables interpretable, robust, and reproducible Simulink simulation generation. Our source code is publicly available at https://github.com/renxinxing123/SimuGen_beta.

This study presents a methodology to treat performance-based seismic design as an inverse engineering problem, where design parameters are directly derived to achieve specific performance objectives. By implementing explainable machine learning models, this methodology directly maps design variables and performance metrics, tackling computational inefficiencies of performance-based design. The resultant machine learning model is integrated as an evaluation function into a genetic optimization algorithm to solve the inverse problem. The developed methodology is then applied to two different inventories of steel and concrete moment frames in Los Angeles and Charleston to obtain sectional properties of frame members that minimize expected annualized seismic loss in terms of repair costs. The results show high accuracy of the surrogate models (e.g., R2> 90%) across a diverse set of building types, geometries, seismic design, and site hazard, where the optimization algorithm could identify the optimum values of members' properties for a fixed set of geometric variables, consistent with engineering principles.

As large language models (LLMs) continue to advance, the need for up-to-date and well-organized benchmarks becomes increasingly critical. However, many existing datasets are scattered, difficult to manage, and make it challenging to perform evaluations tailored to specific needs or domains, despite the growing importance of domain-specific models in areas such as math or code. In this paper, we introduce BenchHub, a dynamic benchmark repository that empowers researchers and developers to evaluate LLMs more effectively. BenchHub aggregates and automatically classifies benchmark datasets from diverse domains, integrating 303K questions across 38 benchmarks. It is designed to support continuous updates and scalable data management, enabling flexible and customizable evaluation tailored to various domains or use cases. Through extensive experiments with various LLM families, we demonstrate that model performance varies significantly across domain-specific subsets, emphasizing the importance of domain-aware benchmarking. We believe BenchHub can encourage better dataset reuse, more transparent model comparisons, and easier identification of underrepresented areas in existing benchmarks, offering a critical infrastructure for advancing LLM evaluation research.

Research on metaphor has steadily increased over the last decades, as this phenomenon opens a window into a range of processes in language and cognition, from pragmatic inference to abstraction and embodied simulation. At the same time, the demand for rigorously constructed and extensively normed experimental materials increased as well. Here, we present the Figurative Archive, an open database of 997 metaphors in Italian enriched with rating and corpus-based measures (from familiarity to lexical frequency), derived by collecting stimuli used across 11 studies. It includes both everyday and literary metaphors, varying in structure and semantic domains. Dataset validation comprised correlations between familiarity and other measures. The Figurative Archive has several aspects of novelty: it is increased in size compared to previous resources; it includes a novel measure of inclusiveness, to comply with current recommendations for non-discriminatory language use; it is displayed in a web-based interface, with features for a flexible and customized consultation. We provide guidelines for using the Archive in future metaphor studies, in the spirit of open science.