Many sequential decision settings in healthcare feature funnel structures characterized by a series of stages, such as screenings or evaluations, where the number of patients who advance to each stage progressively decreases and decisions become increasingly costly. For example, an oncologist may first conduct a breast exam, followed by a mammogram for patients with concerning exams, followed by a biopsy for patients with concerning mammograms. A key challenge is that the ground truth outcome, such as the biopsy result, is only revealed at the end of this funnel. The selective censoring of the ground truth can introduce statistical biases in risk estimation, especially in underserved patient groups, whose outcomes are more frequently censored. We develop a Bayesian model for funnel decision structures, drawing from prior work on selective labels and censoring. We first show in synthetic settings that our model is able to recover the true parameters and predict outcomes for censored patients more accurately than baselines. We then apply our model to a dataset of emergency department visits, where in-hospital mortality is observed only for those who are admitted to either the hospital or ICU. We find that there are gender-based differences in hospital and ICU admissions. In particular, our model estimates that the mortality risk threshold to admit women to the ICU is higher for women (5.1%) than for men (4.5%).

E-14 F Reward Evaluation and Customization F-19 F.1 Load Shifting Penalty ( LS F-19 F.2 Default Reward Function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . F-19 F.3 Customization of Reward Formulations . . . . . . . . . . . . . . . . . . . . . . . Current Workload - The current workload level, which includes both flexible and non-flexible components. The data center modeled is illustrated in Figure 1. The hot air exits the cabinets and returns to the CRAH via the ceiling.

We develop the strategy of linear component operations that integrates dynamic programming technique and the push-relabel approach.

Traditional PID controllers have limited adaptability for plasma shape control, and task-specific reinforcement learning (RL) methods suffer from limited generalization and the need for repetitive retraining. To overcome these challenges, this paper proposes a novel framework for developing a versatile, zero-shot control policy from a large-scale offline dataset of historical PID-controlled discharges. Our approach synergistically combines Generative Adversarial Imitation Learning (GAIL) with Hilbert space representation learning to achieve dual objectives: mimicking the stable operational style of the PID data and constructing a geometrically structured latent space for efficient, goal-directed control. The resulting foundation policy can be deployed for diverse trajectory tracking tasks in a zero-shot manner without any task-specific fine-tuning. Evaluations on the HL-3 tokamak simulator demonstrate that the policy excels at precisely and stably tracking reference trajectories for key shape parameters across a range of plasma scenarios. This work presents a viable pathway toward developing highly flexible and data-efficient intelligent control systems for future fusion reactors.

E-14 F Reward Evaluation and Customization F-19 F.1 Load Shifting Penalty ( LS F-19 F.2 Default Reward Function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . F-19 F.3 Customization of Reward Formulations . . . . . . . . . . . . . . . . . . . . . . . Current Workload - The current workload level, which includes both flexible and non-flexible components. The data center modeled is illustrated in Figure 1. The hot air exits the cabinets and returns to the CRAH via the ceiling.

Tab. 4 provides detailed statistics of the two datasets. B.2 Clinical Predictive T asks We focus on two common clinical predictive tasks: readmission prediction and mortality prediction. In the case of the eICU dataset, the predictions are made 12 hours after admission. The overall prevalence for these tasks is 15% for readmission and 4% for mortality. For the MIMIC-IV dataset, the predictions are made at the time of discharge.

Multi-agent social interaction has clearly benefited from Large Language Models. However, current simulation systems still face challenges such as difficulties in scaling to diverse scenarios and poor reusability due to a lack of modular design. To address these issues, we designed and developed a modular, object-oriented framework that organically integrates various base classes through a hierarchical structure, harvesting scalability and reusability. We inherited the framework to realize common derived classes. Additionally, a memory summarization mechanism is proposed to filter and distill relevant information from raw memory data, prioritizing contextually salient events and interactions. By selecting and combining some necessary derived classes, we customized a specific simulated environment. Utilizing this simulated environment, we successfully simulated human interactions on social media, replicating real-world online social behaviors. The source code for the project will be released and evolve.

In electricity markets around the world, the ability to anticipate price movements with precision can be the difference between profit and loss, especially for fast-acting assets like battery energy storage systems (BESS). As grid volatility increases due to renewables and market decentralisation, operators and forecasters alike face growing pressure to transform prediction into strategy. Yet while forecast data is abundant, especially in advanced markets like Australia's National Electricity Market (NEM), its practical value in driving real-world BESS trading decisions remains largely unexplored. This thesis dives into that gap. This work addresses a key research question: Can the accuracy of the Australian Energy Market Operator (AEMO) energy price forecasts be systematically leveraged to develop a reliable and profitable battery energy storage system trading algorithm? Despite the availability of AEMO price forecasts, no existing framework evaluates their reliability or incorporates them into practical BESS trading strategies. By analysing patterns in forecast accuracy based on time of day, forecast horizon, and regional variations, this project creates a novel, forecast-informed BESS trading model to optimise arbitrage financial returns. The performance of this forecast-driven algorithm is benchmarked against a basic trading algorithm with no knowledge of forecast data. The study further explores the potential of machine learning techniques to predict future energy prices by enhancing AEMO forecasts to govern a more advanced trading strategy. The research outcomes will inform future improvements in energy market trading models and promote more efficient BESS integration into market operations.

Closed -loop brain stimulation holds potential as personalized treatment for drug-resistant epilepsy (DRE) but still suffers from limitations that result in highly variable efficacy. First, stimulation is typically delivered upon detection of the seizure to abort rather than prevent it; second, the stimulation parameters are established by trial and error, requiring lengthy rounds of fine -tuning, which delay steady-state therapeutic efficacy. Here, we address these limitations by leveraging the potential of neuromorphic computing. We present a neuromorphic reservoir computing hardware system capable of driving real - time personalized free-run stimulations based on seizure forecasting, wherein each forecast triggers an electrical pulse rather than an arbitrarily predefined fixed -frequency stimulus train. The system achieves 83.33% accuracy in forecasting seizure occurrences during the training phase. We validate the system using hippocampal spheroids coupled to 3D microelectrode array as a simplified testbed, achieving seizure reduction >97% during the real -time processing while primarily using instantaneous stimulation frequencies within 20 Hz, well below what typically used in clinical practice. Our work demonstrates the potential of neuromorphic systems as a next -generation neuromodulation strategy for personalized DRE treatment, leveraging their sparse and event-driven processing for real -time applications. Keywords: Neuromorphic system, drug-resistant epilepsy, seizure forecasting, neuromodulation, closed -loop stimulation, edge-devices.