In this applied paper, we address the difficult open problem of when to discharge patients from the Intensive Care Unit. This can be conceived as an optimal stopping scenario with three added challenges: 1) the evaluation of a stopping strategy from observational data is itself a complex causal inference problem, 2) the composite objective is to minimize the length of intervention and maximize the outcome, but the two cannot be collapsed to a single dimension, and 3) the recording of variables stops when the intervention is discontinued. Our contributions are two-fold. First, we generalize the implementation of the g-formula Python package, providing a framework to evaluate stopping strategies for problems with the aforementioned structure, including positivity and coverage checks. Second, with a fully open-source pipeline, we apply this approach to MIMIC-IV, a public ICU dataset, demonstrating the potential for strategies that improve upon current care.

We develop the strategy of linear component operations thatintegrates dynamic programming techniqueandthepush-relabel approach.

NASA astronaut Nichole Ayers spotted the summer storm while aboard the International Space Station. Breakthroughs, discoveries, and DIY tips sent every weekday. Lightning is one of Earth's most impressive phenomena. The sudden discharges of superheated plasma occur even in seemingly sunny conditions, rip apart air molecules, and can easily span hundreds of miles . But while there is still a lot to learn about lightning from our perspective here on Earth, there's also much to glean by observing it from high above.

Many sequential decision settings in healthcare feature funnel structures characterized by a series of stages, such as screenings or evaluations, where the number of patients who advance to each stage progressively decreases and decisions become increasingly costly. For example, an oncologist may first conduct a breast exam, followed by a mammogram for patients with concerning exams, followed by a biopsy for patients with concerning mammograms. A key challenge is that the ground truth outcome, such as the biopsy result, is only revealed at the end of this funnel. The selective censoring of the ground truth can introduce statistical biases in risk estimation, especially in underserved patient groups, whose outcomes are more frequently censored. We develop a Bayesian model for funnel decision structures, drawing from prior work on selective labels and censoring. We first show in synthetic settings that our model is able to recover the true parameters and predict outcomes for censored patients more accurately than baselines. We then apply our model to a dataset of emergency department visits, where in-hospital mortality is observed only for those who are admitted to either the hospital or ICU. We find that there are gender-based differences in hospital and ICU admissions. In particular, our model estimates that the mortality risk threshold to admit women to the ICU is higher for women (5.1%) than for men (4.5%).

Traditional PID controllers have limited adaptability for plasma shape control, and task-specific reinforcement learning (RL) methods suffer from limited generalization and the need for repetitive retraining. To overcome these challenges, this paper proposes a novel framework for developing a versatile, zero-shot control policy from a large-scale offline dataset of historical PID-controlled discharges. Our approach synergistically combines Generative Adversarial Imitation Learning (GAIL) with Hilbert space representation learning to achieve dual objectives: mimicking the stable operational style of the PID data and constructing a geometrically structured latent space for efficient, goal-directed control. The resulting foundation policy can be deployed for diverse trajectory tracking tasks in a zero-shot manner without any task-specific fine-tuning. Evaluations on the HL-3 tokamak simulator demonstrate that the policy excels at precisely and stably tracking reference trajectories for key shape parameters across a range of plasma scenarios. This work presents a viable pathway toward developing highly flexible and data-efficient intelligent control systems for future fusion reactors.

E-14 F Reward Evaluation and Customization F-19 F.1 Load Shifting Penalty ( LS F-19 F.2 Default Reward Function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . F-19 F.3 Customization of Reward Formulations . . . . . . . . . . . . . . . . . . . . . . . Current Workload - The current workload level, which includes both flexible and non-flexible components. The data center modeled is illustrated in Figure 1. The hot air exits the cabinets and returns to the CRAH via the ceiling.

Tab. 4 provides detailed statistics of the two datasets. B.2 Clinical Predictive T asks We focus on two common clinical predictive tasks: readmission prediction and mortality prediction. In the case of the eICU dataset, the predictions are made 12 hours after admission. The overall prevalence for these tasks is 15% for readmission and 4% for mortality. For the MIMIC-IV dataset, the predictions are made at the time of discharge.

Multi-agent social interaction has clearly benefited from Large Language Models. However, current simulation systems still face challenges such as difficulties in scaling to diverse scenarios and poor reusability due to a lack of modular design. To address these issues, we designed and developed a modular, object-oriented framework that organically integrates various base classes through a hierarchical structure, harvesting scalability and reusability. We inherited the framework to realize common derived classes. Additionally, a memory summarization mechanism is proposed to filter and distill relevant information from raw memory data, prioritizing contextually salient events and interactions. By selecting and combining some necessary derived classes, we customized a specific simulated environment. Utilizing this simulated environment, we successfully simulated human interactions on social media, replicating real-world online social behaviors. The source code for the project will be released and evolve.