Breakthroughs, discoveries, and DIY tips sent six days a week. The is one of evolution's most infamous species--but it's also a very confusing creature. All present-day birds are technically dinosaurs, but the 150-million-year-old, raven-sized hunter is the earliest known example of an avian animal. At the same time, lived during the Jurassic Period among multiple other feathered dinosaurs that were birds in the true sense of the term. But if it's any consolation, it's often still difficult for paleontologists to tell them apart, too.

Biclustering is the analog of clustering on a bipartite graph. Existent methods infer biclusters through local search strategies that find one cluster at a time; a common technique is to update the row memberships based on the current column memberships, and vice versa. We propose a biclustering algorithm that maximizes a global objective function using message passing. Our objective function closely approximates a general likelihood function, separating a cluster size penalty term into row-and column-count penalties. Because we use a global optimization framework, our approach excels at resolving the overlaps between biclusters, which are important features of biclusters in practice. Moreover, Expectation-Maximization can be used to learn the model parameters if they are unknown. In simulations, we find that our method outperforms two of the best existing biclustering algorithms, ISA and LAS, when the planted clusters overlap. Applied to three gene expression datasets, our method finds coregulated gene clusters that have high quality in terms of cluster size and density.

Science Dinosaurs Why did this ancient bird die with tiny rocks in its throat? The 120-million-year-old fossil may also be a choking hazard PSA. Breakthroughs, discoveries, and DIY tips sent every weekday. Fossils may reveal what type of animal died millions of years ago, but they rarely depict exactly they perished. Even rarer are the examples that clearly showcase an animal's exact cause of death.

Biclustering is the analog of clustering on a bipartite graph. Existent methods infer biclusters through local search strategies that find one cluster at a time; a common technique is to update the row memberships based on the current column memberships, and vice versa. We propose a biclustering algorithm that maximizes a global objective function using message passing. Our objective function closely approximates a general likelihood function, separating a cluster size penalty term into row-and column-count penalties. Because we use a global optimization framework, our approach excels at resolving the overlaps between biclusters, which are important features of biclusters in practice. Moreover, Expectation-Maximization can be used to learn the model parameters if they are unknown. In simulations, we find that our method outperforms two of the best existing biclustering algorithms, ISA and LAS, when the planted clusters overlap. Applied to three gene expression datasets, our method finds coregulated gene clusters that have high quality in terms of cluster size and density.

When the air ambulance brought Jim Ashworth-Beaumont to King's College hospital in south-east London, nobody thought he had a hope. He had been cycling home when a lorry driver failed to spot him alongside his trailer while turning left after a set of traffic lights. The vehicle's wheels opened his torso like a sardine tin, puncturing his lungs and splitting his liver in two. They also tore off his right arm. Weeks after the accident, in July 2020, Ashworth-Beaumont would see a photo of the severed limb taken by a doctor while it lay beside him in hospital. He had asked to see the picture and says it helped him come to terms with his loss. "My hand didn't look too bad," he says. "It was as if it was waving goodbye to me." Ashworth-Beaumont, a super-fit and sunny former Royal Marine from Edinburgh, would go on to spend six weeks in an induced coma as surgeons raced to repair his crushed body. But as he lay on the road, waiting for the paramedics, his only thoughts were that he was dying.

The'Outnumbered' panel reacts to the House Oversight Committee's move to subpoena former President Joe Biden's doctor amid concerns about his mental fitness during his time in office. Former President Barack Obama's White House physician said in a new interview that former President Joe Biden's doctor should have performed a cognitive test to evaluate his fitness to serve in office. Obama's doctor, Jeffrey Kuhlman, told The Washington Post that Biden White House physician Kevin O'Connor should have performed a cognitive test during Biden's last year as president, given his age. O'Connor, who Kuhlman first appointed as Biden's doctor in 2009 when he was vice president, declared in a 2024 report that the then-81-year-old president "continues to be fit for duty." The report did not mention any neurocognitive testing.

Scientists have discovered a new brain glitch that is the exact opposite of deja vu. While deja vu is the unsettling sense that you've lived a moment before, jamais vu is when something familiar suddenly feels alien -- like encountering it for the very first time. You've likely felt it: walking through your hometown and suddenly feeling lost, or repeating a common word until it sounds strange and meaningless. Repetition is often the trigger. The brain, overloaded by familiarity, short-circuits, making the ordinary feel bizarre.

I stand in the darkened silence of a rectangular chamber, 8 meters long and 6 meters wide, balanced on the tips of my toes. On the wall in front of me are the outlines of two circles. Beyond these walls is an enormous insulated hangar decked with artificial grass and filled with highly paid professional soccer players. I brace, as though waiting for the Death Star to ready its superlaser. I turn, and it takes another two touches before I've brought the ball fully under my control. A professional player would have managed it in one, and would have done so without making a sound.

Do you know that strange sensation of walking into a room and feeling like you've been there before, even though you know you haven't? Or when you hear someone say something for the first time, but there's a certain familiarity to it that gives you pause? That's déjà vu–a phenomenon that's not well understood, but scientists have some ideas. Déjà vu is the eerie feeling that you have had the same novel experience before. It's a spontaneous, elusive sensation that reveals the workings of consciousness, allowing us to see the separation between what we feel and what we know to be true, explains Akira O'Connor, a psychologist and senior lecturer at the University of St. Andrews School of Psychology and Neuroscience.

White House press secretary Karine Jean-Pierre on Monday said that President Biden will not be taking a cognitive test during his regular physical exam. President Biden will not take a cognitive test as part of his upcoming physical exam, the White House confirmed Monday. White House press secretary Karine Jean-Pierre stated that Biden's physician, Dr. Kevin O'Connor, does not believe a cognitive test is necessary. She said O'Connor believes Biden proves his cognitive ability "every day [in] how he operates and how he thinks." Reporters pressed Jean-Pierre on the issue due to last week's report from Special Counsel Robert Hur that found Biden has significant memory issues.