We present Pre-trained Machine Reader (PMR), a novel method for retrofitting pre-trained masked language models (MLMs) to pre-trained machine reading comprehension (MRC) models without acquiring labeled data.PMR can resolve the discrepancy between model pre-training and downstream fine-tuning of existing MLMs.To build the proposed PMR, we constructed a large volume of general-purpose and high-quality MRC-style training data by using Wikipedia hyperlinks and designed a Wiki Anchor Extraction task to guide the MRC-style pre-training.Apart from its simplicity, PMR effectively solves extraction tasks, such as Extractive Question Answering and Named Entity Recognition. PMR shows tremendous improvements over existing approaches, especially in low-resource scenarios.When applied to the sequence classification task in the MRC formulation, PMR enables the extraction of high-quality rationales to explain the classification process, thereby providing greater prediction explainability. PMR also has the potential to serve as a unified model for tackling various extraction and classification tasks in the MRC formulation.

Integrating novel medical concepts and relationships into existing ontologies can significantly enhance their coverage and utility for both biomedical research and clinical applications. Clinical notes, as unstructured documents rich with detailed patient observations, offer valuable context-specific insights and represent a promising yet underutilized source for ontology extension. Despite this potential, directly leveraging clinical notes for ontology extension remains largely unexplored. To address this gap, we propose CLOZE, a novel framework that uses large language models (LLMs) to automatically extract medical entities from clinical notes and integrate them into hierarchical medical ontologies. By capitalizing on the strong language understanding and extensive biomedical knowledge of pre-trained LLMs, CLOZE effectively identifies disease-related concepts and captures complex hierarchical relationships. The zero-shot framework requires no additional training or labeled data, making it a cost-efficient solution. Furthermore, CLOZE ensures patient privacy through automated removal of protected health information (PHI). Experimental results demonstrate that CLOZE provides an accurate, scalable, and privacy-preserving ontology extension framework, with strong potential to support a wide range of downstream applications in biomedical research and clinical informatics.

Generative models such as Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs) trained on massive datasets can lead them to memorize and inadvertently reveal sensitive information, raising ethical and privacy concerns. While some prior works have explored this issue in the context of LLMs, it presents a unique challenge for MLLMs due to the entangled nature of knowledge across modalities, making comprehensive unlearning more difficult. To address this challenge, we propose Modality Aware Neuron Unlearning (MANU), a novel unlearning framework for MLLMs designed to selectively clip neurons based on their relative importance to the targeted forget data, curated for different modalities. Specifically, MANU consists of two stages: important neuron selection and selective pruning. The first stage identifies and collects the most influential neurons across modalities relative to the targeted forget knowledge, while the second stage is dedicated to pruning those selected neurons. MANU effectively isolates and removes the neurons that contribute most to the forget data within each modality, while preserving the integrity of retained knowledge. Our experiments conducted across various MLLM architectures illustrate that MANU can achieve a more balanced and comprehensive unlearning in each modality without largely affecting the overall model utility.

We present Pre-trained Machine Reader (PMR), a novel method for retrofitting pre-trained masked language models (MLMs) to pre-trained machine reading comprehension (MRC) models without acquiring labeled data.PMR can resolve the discrepancy between model pre-training and downstream fine-tuning of existing MLMs.To build the proposed PMR, we constructed a large volume of general-purpose and high-quality MRC-style training data by using Wikipedia hyperlinks and designed a Wiki Anchor Extraction task to guide the MRC-style pre-training.Apart from its simplicity, PMR effectively solves extraction tasks, such as Extractive Question Answering and Named Entity Recognition. PMR shows tremendous improvements over existing approaches, especially in low-resource scenarios.When applied to the sequence classification task in the MRC formulation, PMR enables the extraction of high-quality rationales to explain the classification process, thereby providing greater prediction explainability. PMR also has the potential to serve as a unified model for tackling various extraction and classification tasks in the MRC formulation.

The issue of factual consistency in abstractive summarization has received extensive attention in recent years, and the evaluation of factual consistency between summary and document has become an important and urgent task. Most of the current evaluation metrics are adopted from the question answering (QA) or natural language inference (NLI) task. However, the application of QA-based metrics is extremely time-consuming in practice while NLI-based metrics are lack of interpretability. In this paper, we propose a cloze-based evaluation framework called ClozE and show the great potential of the cloze-based metric. It inherits strong interpretability from QA, while maintaining the speed of NLI- level reasoning. We demonstrate that ClozE can reduce the evaluation time by nearly 96% relative to QA-based metrics while retaining their interpretability and performance through experiments on six human-annotated datasets and a meta-evaluation benchmark GO FIGURE (Gabriel et al., 2021). Finally, we discuss three important facets of ClozE in practice, which further shows better overall performance of ClozE compared to other metrics.

Existing pre-training methods for extractive Question Answering (QA) generate cloze-like queries different from natural questions in syntax structure, which could overfit pre-trained models to simple keyword matching. In order to address this problem, we propose a novel Momentum Contrastive pRe-training fOr queStion anSwering (MCROSS) method for extractive QA. Specifically, MCROSS introduces a momentum contrastive learning framework to align the answer probability between cloze-like and natural query-passage sample pairs. Hence, the pre-trained models can better transfer the knowledge learned in cloze-like samples to answering natural questions. Experimental results on three benchmarking QA datasets show that our method achieves noticeable improvement compared with all baselines in both supervised and zero-shot scenarios.

We present KERMIT, a simple insertion-based approach to generative modeling for sequences and sequence pairs. KERMIT models the joint distribution and its decompositions (i.e., marginals and conditionals) using a single neural network and, unlike much prior work, does not rely on a prespecified factorization of the data distribution. During training, one can feed KERMIT paired data $(x, y)$ to learn the joint distribution $p(x, y)$, and optionally mix in unpaired data $x$ or $y$ to refine the marginals $p(x)$ or $p(y)$. During inference, we have access to the conditionals $p(x \mid y)$ and $p(y \mid x)$ in both directions. We can also sample from the joint distribution or the marginals. The model supports both serial fully autoregressive decoding and parallel partially autoregressive decoding, with the latter exhibiting an empirically logarithmic runtime. We demonstrate through experiments in machine translation, representation learning, and zero-shot cloze question answering that our unified approach is capable of matching or exceeding the performance of dedicated state-of-the-art systems across a wide range of tasks without the need for problem-specific architectural adaptation.