Stranded tourists flee for their lives by boat as'apocalyptic mega-fire' triggers total evacuation of'French Hamptons' Bargain hunter bought Connecticut mansion for a pittance only to find family decomposing inside. Why Tom Brady's midlife crisis after Gisele Bundchen divorce threatens to ruin his legacy... and he doesn't care! Jon Bon Jovi, 64, abruptly stops NYC concert and tells audience he is'hurt' before leaving the stage So much has never been made public': Insiders at very top of Hollywood tell me bombshell twist that flips Taylor Swift-Lively feud on its head: ROB SHUTER McDonald's copies Costco with its newest menu item and fans have mixed reactions Meghan and Harry share snaps of their European summer holiday as pro-Sussex People magazine reveals they stayed at Princess Diana's childhood home with Archie and Lilibet House of Horrors mom insists her kids were NOT'feral', as lawyer reveals her incredulous excuse for their'messy' home The age when you must give up smoking to escape the risk of lung cancer: Experts reveal the truth about what quitting does to your body in your 30s, 40s, and 50s... and the REAL impact of that one cheeky cigarette a week White House defends Sophie Cunningham amid woke backlash... as WNBA star doubles down on trans views with new Instagram photos Hot summer snaps of Nicole Kidman getting affectionate with handsome businessman on Italian getaway... as friends speak out about moving on after Keith Urban divorce Robin Thicke's model wife, 31, shows off incredible bikini body after giving birth to three kids as they vacation in Saint-Tropez Harry has reached a new low. It's such a slap in the face to his father... especially after what the King's friend told me: RICHARD EDEN Amal Clooney's diet and fitness regime revealed - and it's surprisingly simple if you don't mind seaweed soup for breakfast! Inside one of sailing's most iconic races: Daily Mail's SHIVALI BEST joins 800 boats battling it out in the Round the Island Race When it comes to iconic British mass-participation sporting events, the London Marathon or the Great North and South Runs might spring to mind.

More than 500 Rohingya vanished at sea - what happened? Two boats carrying an estimated 530 Rohingya asylum seekers left Myanmar's Rakhine state on 29 June, and have not been heard from since. The equivalent of a jumbo jet full of people has vanished. It is very likely that they both capsized. The monsoon has started, the seas are rough, and the boats - usually old fishing trawlers converted to carry as many people as possible - are barely sea-worthy with unreliable engines.

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Iran Is Using Tiny'Mosquito' Boats to Shut Down the Strait of Hormuz Iran's traditional naval fleet has been almost completely destroyed by US-Israeli raids. But Iran's Revolutionary Guard has deployed a fleet of small vessels that is crippling every passageway. In the Strait of Hormuz, Iran has developed an asymmetrical naval strategy that is crippling the passage of container ships. This "hemostat" uses guerrilla tactics, after Iran's "traditional" fleet was almost entirely destroyed by US and Israeli attacks. No longer able to rely on specialized military ships, Tehran is using an unconventional force made up of dozens of small military vessels armed with missiles, machine guns, and drones.

Table 4 contains the full set of topics for the k " 30LDA model introduced in 4.406 Table 4: LDA[6] topic modeling outputs (k=30 topics) when trained on a random sample of documents from mmc4. Topic frequencies are determined by taking the mean distribution over documents in the corpus. Topic names are generated by GPT-4 conditioned on the top 20 words for each topic, prompted by a request for a short 1-2 word summary. Table 5 and Table 6 list the top-50 most frequent top-level domains for documents and images as408 discussed in 4. We show domain statistics in both mmc4and mmc4-core.409 The symbol "*" is employed to denote specific patterns, such as digits or location acronyms, commonly utilized to differentiate sub-sites within the same domain.

Antibody lead optimization is inherently a multi-objective challenge in drug discovery. Achieving a balance between different drug-like properties is crucial for the development of viable candidates, and this search becomes exponentially challenging as desired properties grow. The ever-growing zoo of sophisticated in silico tools for predicting antibody properties calls for an efficient joint optimization procedure to overcome resource-intensive sequential filtering pipelines. We present BOAT, a versatile Bayesian optimization framework for multi-property antibody engineering. Our `plug-and-play' framework couples uncertainty-aware surrogate modeling with a genetic algorithm to jointly optimize various predicted antibody traits while enabling efficient exploration of sequence space. Through systematic benchmarking against genetic algorithms and newer generative learning approaches, we demonstrate competitive performance with state-of-the-art methods for multi-objective protein optimization. We identify clear regimes where surrogate-driven optimization outperforms expensive generative approaches and establish practical limits imposed by sequence dimensionality and oracle costs.

Iranian forces deploy explosive drone boats disguised as fishing vessels in Strait of Hormuz, defense expert Cameron Chell warns, marking new phase of hybrid warfare.

Fast, stealthy, and cheap--autonomous, semisubmersible drone boats carrying tons of cocaine could be international law enforcement's nightmare scenario. A big one just came ashore. Colombian military officials intercepted this 40-foot-long uncrewed fiberglass "narco sub" in the ocean just off Tayrona National Park. On a bright morning last April, a surveillance plane operated by the Colombian military spotted a 40-foot-long shark-like silhouette idling in the ocean just off Tayrona National Park. It was, unmistakably, a "narco sub," a stealthy fiberglass vessel that sails with its hull almost entirely underwater, used by drug cartels to move cocaine north. The plane's crew radioed it in, and eventually nearby coast guard boats got the order, routine but urgent: Intercept. In Cartagena, about 150 miles from the action, Captain Jaime González Zamudio, commander of the regional coast guard group, sat down at his desk to watch what happened next.

We expand Eq. 10 as: q There are three KL divergence terms in our training objective ELBO (Eq. Medium and Y elp Large datasets, we follow (Guu et al., 2018) to use a three-layer attentional LSTM Skip connections are also used between adjacent LSTM layers. We apply annealing and free-bits techniques following (Li et al., 2019) to the KL term on prototype variable, As in Section 4.3, here we show more generated examples through interpolation on MSCOCO dataset. Table 6: Qualitative examples from the MSCOCO dataset on interpolated sentence generation given the prototype.