Bivariate partial information decomposition (PID) has emerged as a promising tool for analyzing interactions in complex systems, particularly in neuroscience. PID achieves this by decomposing the information that two sources (e.g., different

We propose a constructive algorithm for identifying complete data distributions in graphical models of missing data. The complete data distribution is unrestricted, while the missingness mechanism is assumed to factorize according to a conditional directed acyclic graph. Our approach follows an interventionist perspective in which missingness indicators are treated as variables that can be intervened on. A central challenge in this setting is that sequences of interventions on missingness indicators may induce and propagate selection bias, so that identification can fail even when a propensity score is invariant to available interventions. To address this challenge, we introduce a tree-based identification algorithm that explicitly tracks the creation and propagation of selection bias and determines whether it can be avoided through admissible intervention strategies. The resulting tree provides both a diagnostic and a constructive characterization of identifiability under a given missingness mechanism. Building on these results, we develop recursive inverse probability weighting procedures that mirror the intervention logic of the identification algorithm, yielding valid estimating equations for both the missingness mechanism and functionals of the complete data distribution. Simulation studies and a real-data application illustrate the practical performance of the proposed methods. An accompanying R package, flexMissing, implements all proposed procedures.

Our experiments show that Genfer is often faster than the existing exact inference tools PSI, Dice, and Prodigy.

This paper presents a real time, data driven decision support framework for epidemic control. We combine a compartmental epidemic model with sequential Bayesian inference and reinforcement learning (RL) controllers that adaptively choose intervention levels to balance disease burden, such as intensive care unit (ICU) load, against socio economic costs. We construct a context specific cost function using empirical experiments and expert feedback. We study two RL policies: an ICU threshold rule computed via Monte Carlo grid search, and a policy based on a posterior averaged Q learning agent. We validate the framework by fitting the epidemic model to publicly available ICU occupancy data from the COVID 19 pandemic in England and then generating counterfactual roll out scenarios under each RL controller, which allows us to compare the RL policies to the historical government strategy. Over a 300 day period and for a range of cost parameters, both controllers substantially reduce ICU burden relative to the observed interventions, illustrating how Bayesian sequential learning combined with RL can support the design of epidemic control policies.

Neural Information Processing Systems http://nips.cc/

We evaluate the performance of targeted maximum likelihood estimation (TMLE) for estimating the average treatment effect in missing data scenarios under varying levels of positivity violations. We employ model- and design-based simulations, with the latter using undersmoothed highly adaptive lasso on the 'WASH Benefits Bangladesh' dataset to mimic real-world complexities. Five missingness-directed acyclic graphs are considered, capturing common missing data mechanisms in epidemiological research, particularly in one-point exposure studies. These mechanisms include also not-at-random missingness in the exposure, outcome, and confounders. We compare eight missing data methods in conjunction with TMLE as the analysis method, distinguishing between non-multiple imputation (non-MI) and multiple imputation (MI) approaches. The MI approaches use both parametric and machine-learning models. Results show that non-MI methods, particularly complete cases with TMLE incorporating an outcome-missingness model, exhibit lower bias compared to all other evaluated missing data methods and greater robustness against positivity violations across. In Comparison MI with classification and regression trees (CART) achieve lower root mean squared error, while often maintaining nominal coverage rates. Our findings highlight the trade-offs between bias and coverage, and we recommend using complete cases with TMLE incorporating an outcome-missingness model for bias reduction and MI CART when accurate confidence intervals are the priority.

Bivariate partial information decomposition (PID) has emerged as a promising tool for analyzing interactions in complex systems, particularly in neuroscience. PID achieves this by decomposing the information that two sources (e.g., different