The potential benefits of mining social media to learn about adverse drug reactions (ADRs) are rapidly increasing with the increasing popularity of social media. Unknown ADRs have traditionally been discovered by expensive post-marketing trials, but recent work has suggested that some unknown ADRs may be discovered by analyzing social media. We propose three methods for extracting ADRs from forum posts and tweets, and compare our methods with several existing methods. Our methods outperform the existing methods in several scenarios; our filtering method achieves the highest F1 and precision on forum posts, and our CRF method achieves the highest precision on tweets. Furthermore, we address the difficulty of annotating social media on a large scale with an alternate evaluation scheme that takes advantage of the ADRs listed on drug labels. We investigate how well this alternate evaluation approximates a traditional evaluation using human annotations.

Full natural language understanding requires identifying and analyzing the meanings of metaphors, which are ubiquitous in both text and speech. Over the last thirty years, linguistic metaphors have been shown to be based on more general conceptual metaphors, partial semantic mappings between disparate conceptual domains. Though some achievements have been made in identifying linguistic metaphors over the last decade or so, little work has been done to date on automatically identifying conceptual metaphors. This paper describes research on identifying conceptual metaphors based on corpus data. Our method uses as little background knowledge as possible, to ease transfer to new languages and to mini- mize any bias introduced by the knowledge base construction process. The method relies on general heuristics for identifying linguistic metaphors and statistical clustering (guided by Wordnet) to form conceptual metaphor candidates. Human experiments show the system effectively finds meaningful conceptual metaphors.