-- Distance-based reward mechanisms in deep reinforcement learning (DRL) navigation systems suffer from critical safety limitations in dynamic environments, frequently resulting in collisions when visibility is restricted. We propose DRL-NSUO, a novel navigation strategy for unexpected obstacles that leverages the rate of change in LiDAR data as a dynamic environmental perception element. Our approach incorporates a composite reward function with environmental change rate constraints and dynamically adjusted weights through curriculum learning, enabling robots to autonomously balance between path efficiency and safety maximization. We enhance sensitivity to nearby obstacles by implementing short-range feature preprocessing of LiDAR data. Experimental results demonstrate that this method significantly improves both robot and pedestrian safety in complex scenarios compared to traditional DRL-based methods. When evaluated on the BARN navigation dataset, our method achieved superior performance with success rates of 94.0% at 0.5 m/s and 91.0% at 1.0 m/s, outperforming conservative obstacle expansion strategies. Deep Reinforcement Learning (DRL) has emerged as a promising approach for navigation in dynamic environments [1].

This work focuses on enhancing the generalization performance of deep reinforcement learning-based robot navigation in unseen environments. We present a novel data augmentation approach called scenario augmentation, which enables robots to navigate effectively across diverse settings without altering the training scenario. The method operates by mapping the robot's observation into an imagined space, generating an imagined action based on this transformed observation, and then remapping this action back to the real action executed in simulation. Through scenario augmentation, we conduct extensive comparative experiments to investigate the underlying causes of suboptimal navigation behaviors in unseen environments. Our analysis indicates that limited training scenarios represent the primary factor behind these undesired behaviors. Experimental results confirm that scenario augmentation substantially enhances the generalization capabilities of deep reinforcement learning-based navigation systems. The improved navigation framework demonstrates exceptional performance by producing near-optimal trajectories with significantly reduced navigation time in real-world applications.

Visually-situated text parsing (VsTP) has recently seen notable advancements, driven by the growing demand for automated document understanding and the emergence of large language models capable of processing document-based questions. While various methods have been proposed to tackle the complexities of VsTP, existing solutions often rely on task-specific architectures and objectives for individual tasks. This leads to modal isolation and complex workflows due to the diversified targets and heterogeneous schemas. In this paper, we introduce OmniParser V2, a universal model that unifies VsTP typical tasks, including text spotting, key information extraction, table recognition, and layout analysis, into a unified framework. Central to our approach is the proposed Structured-Points-of-Thought (SPOT) prompting schemas, which improves model performance across diverse scenarios by leveraging a unified encoder-decoder architecture, objective, and input\&output representation. SPOT eliminates the need for task-specific architectures and loss functions, significantly simplifying the processing pipeline. Our extensive evaluations across four tasks on eight different datasets show that OmniParser V2 achieves state-of-the-art or competitive results in VsTP. Additionally, we explore the integration of SPOT within a multimodal large language model structure, further enhancing text localization and recognition capabilities, thereby confirming the generality of SPOT prompting technique. The code is available at \href{https://github.com/AlibabaResearch/AdvancedLiterateMachinery}{AdvancedLiterateMachinery}.

We introduce Qwen2.5-VL, the latest flagship model of Qwen vision-language series, which demonstrates significant advancements in both foundational capabilities and innovative functionalities. Qwen2.5-VL achieves a major leap forward in understanding and interacting with the world through enhanced visual recognition, precise object localization, robust document parsing, and long-video comprehension. A standout feature of Qwen2.5-VL is its ability to localize objects using bounding boxes or points accurately. It provides robust structured data extraction from invoices, forms, and tables, as well as detailed analysis of charts, diagrams, and layouts. To handle complex inputs, Qwen2.5-VL introduces dynamic resolution processing and absolute time encoding, enabling it to process images of varying sizes and videos of extended durations (up to hours) with second-level event localization. This allows the model to natively perceive spatial scales and temporal dynamics without relying on traditional normalization techniques. By training a native dynamic-resolution Vision Transformer (ViT) from scratch and incorporating Window Attention, we reduce computational overhead while maintaining native resolution. As a result, Qwen2.5-VL excels not only in static image and document understanding but also as an interactive visual agent capable of reasoning, tool usage, and task execution in real-world scenarios such as operating computers and mobile devices. Qwen2.5-VL is available in three sizes, addressing diverse use cases from edge AI to high-performance computing. The flagship Qwen2.5-VL-72B model matches state-of-the-art models like GPT-4o and Claude 3.5 Sonnet, particularly excelling in document and diagram understanding. Additionally, Qwen2.5-VL maintains robust linguistic performance, preserving the core language competencies of the Qwen2.5 LLM.

Artificial intelligence (AI) has been widely applied in drug discovery with a major task as molecular property prediction. Despite booming techniques in molecular representation learning, key elements underlying molecular property prediction remain largely unexplored, which impedes further advancements in this field. Herein, we conduct an extensive evaluation of representative models using various representations on the MoleculeNet datasets, a suite of opioids-related datasets and two additional activity datasets from the literature. To investigate the predictive power in low-data and high-data space, a series of descriptors datasets of varying sizes are also assembled to evaluate the models. In total, we have trained 62,820 models, including 50,220 models on fixed representations, 4,200 models on SMILES sequences and 8,400 models on molecular graphs. Based on extensive experimentation and rigorous comparison, we show that representation learning models exhibit limited performance in molecular property prediction in most datasets. Besides, multiple key elements underlying molecular property prediction can affect the evaluation results. Furthermore, we show that activity cliffs can significantly impact model prediction. Finally, we explore into potential causes why representation learning models can fail and show that dataset size is essential for representation learning models to excel.

Speech enhancement is a demanding task in automated speech processing pipelines, focusing on separating clean speech from noisy channels. Transformer based models have recently bested RNN and CNN models in speech enhancement, however at the same time they are much more computationally expensive and require much more high quality training data, which is always hard to come by. In this paper, we present an improvement for speech enhancement models that maintains the expressiveness of self-attention while significantly reducing model complexity, which we have termed Spectrum Attention Fusion. We carefully construct a convolutional module to replace several self-attention layers in a speech Transformer, allowing the model to more efficiently fuse spectral features. Our proposed model is able to achieve comparable or better results against SOTA models but with significantly smaller parameters (0.58M) on the Voice Bank + DEMAND dataset.

Most models of visual attention are aimed at predicting either top-down or bottom-up control, as studied using different visual search and free-viewing tasks. We propose Human Attention Transformer (HAT), a single model predicting both forms of attention control. HAT is the new state-of-the-art (SOTA) in predicting the scanpath of fixations made during target-present and target-absent search, and matches or exceeds SOTA in the prediction of taskless free-viewing fixation scanpaths. HAT achieves this new SOTA by using a novel transformer-based architecture and a simplified foveated retina that collectively create a spatio-temporal awareness akin to the dynamic visual working memory of humans. Unlike previous methods that rely on a coarse grid of fixation cells and experience information loss due to fixation discretization, HAT features a dense-prediction architecture and outputs a dense heatmap for each fixation, thus avoiding discretizing fixations. HAT sets a new standard in computational attention, which emphasizes both effectiveness and generality. HAT's demonstrated scope and applicability will likely inspire the development of new attention models that can better predict human behavior in various attention-demanding scenarios.

Artificial intelligence (AI) has been transforming the practice of drug discovery in the past decade. Various AI techniques have been used in a wide range of applications, such as virtual screening and drug design. In this perspective, we first give an overview on drug discovery and discuss related applications, which can be reduced to two major tasks, i.e., molecular property prediction and molecule generation. We then discuss common data resources, molecule representations and benchmark platforms. Furthermore, to summarize the progress in AI-driven drug discovery, we present the relevant AI techniques including model architectures and learning paradigms in the surveyed papers. We expect that the perspective will serve as a guide for researchers who are interested in working at this intersected area of artificial intelligence and drug discovery. We also provide a GitHub repository\footnote{\url{https://github.com/dengjianyuan/Survey_AI_Drug_Discovery}} with the collection of papers and codes, if applicable, as a learning resource, which will be regularly updated.