Digital Behavior Change Interventions (DBCIs) are supporting development of new health behaviors. Evaluating their effectiveness is crucial for their improvement and understanding of success factors. However, comprehensive guidance for developers, particularly in small-scale studies with ethical constraints, is limited. Building on the CAPABLE project, this study aims to define effective engagement with DBCIs for supporting cancer patients in enhancing their quality of life. We identify metrics for measuring engagement, explore the interest of both patients and clinicians in DBCIs, and propose hypotheses for assessing the impact of DBCIs in such contexts. Our findings suggest that clinician prescriptions significantly increase sustained engagement with mobile DBCIs. In addition, while one weekly engagement with a DBCI is sufficient to maintain well-being, transitioning from extrinsic to intrinsic motivation may require a higher level of engagement.

Ontologies play a crucial role in organizing and representing knowledge. However, even current ontologies do not encompass all relevant concepts and relationships. Here, we explore the potential of large language models (LLM) to expand an existing ontology in a semi-automated fashion. We demonstrate our approach on the biomedical ontology SNOMED-CT utilizing semantic relation types from the widely used UMLS semantic network. We propose a method that uses conversational interactions with an LLM to analyze clinical practice guidelines (CPGs) and detect the relationships among the new medical concepts that are not present in SNOMED-CT. Our initial experimentation with the conversational prompts yielded promising preliminary results given a manually generated gold standard, directing our future potential improvements.

We are developing a virtual coaching system that helps patients adhere to behaviour change interventions (BCI). Our proposed system predicts whether a patient will perform the targeted behaviour and uses counterfactual examples with feature control to guide personalisation of BCI. We use simulated patient data with varying levels of receptivity to intervention to arrive at the study design which would enable evaluation of our system.

Increasingly complex learning methods such as boosting, bagging and deep learning have made ML models more accurate, but harder to understand and interpret. A tradeoff between between performance and intelligibility is often to be faced, especially in high-stakes applications like medicine. In the present article we propose a novel methodological approach for generating explanations of the predictions of a generic ML model, given a specific instance for which the prediction has been made, that can tackle both classification and regression tasks. Advantages of the proposed XAI approach include improved fidelity to the original model, ability to deal with non-linear decision boundaries, and native support to both classification and regression problems.

Reports of the Workshops of the Thirty-First AAAI Conference on Artificial Intelligence

The AAAI-17 workshop program included 17 workshops covering a wide range of topics in AI. Workshops were held Sunday and Monday, February 4-5, 2017 at the Hilton San Francisco Union Square in San Francisco, California, USA. This report contains summaries of 12 of the workshops, and brief abstracts of the remaining 5

Atrial fibrillation (AF), the most common arrhythmia with clinical significance, is a serious public health problem. Yet a number of studies show that current AF management is suboptimal due to a knowledge gap between primary care physicians and evidence-based treatment recommendations. This gap is caused by a number of barriers such as a lack of knowledge about new therapies, challenges associated with multi-morbidity, or a lack of patient engagement in therapy planning. The decision support tools proposed to address these barriers handle individual barriers but none of them tackle them comprehensively. Responding to this challenge, we propose AFGuide -- a clinical decision support system to educate and support primary care physicians in developing evidence-based and optimal AF therapies that take into account multi-morbid conditions and patient preferences. AFGuide relies on artificial intelligence techniques (logical reasoning) and preference modeling techniques, and combines them with mobile computing technologies. In this paper we present the design of the system and discuss its proposed implementation and evaluation.

Clinical practice guidelines (CPGs) were originally designed to help with evidence-based management of a single disease and such a single disease focus has impacted research on CPG computerization. This computerization is mostly concerned with supporting different representation formats and identifying potential inconsistencies in the definitions of CPGs. However, one of the biggest challenges facing physicians is the personalization of multiple CPGs to comorbid patients. Various research initiatives propose ways of mitigating adverse interactions in concurrently applied CPGs, however, there are no attempts to develop a generalized framework for mitigation that captures generic characteristics of the problem while handling nuances such as precedence relationships. In this paper we present our research towards developing a mitigation framework that relies on a first-order logic-based representation and related theorem proving and model finding techniques. The application of the proposed framework is illustrated with a simple clinical example.