Wiestler, Bene
TotalVibeSegmentator: Full Torso Segmentation for the NAKO and UK Biobank in Volumetric Interpolated Breath-hold Examination Body Images
Graf, Robert, Platzek, Paul-Sören, Riedel, Evamaria Olga, Ramschütz, Constanze, Starck, Sophie, Möller, Hendrik Kristian, Atad, Matan, Völzke, Henry, Bülow, Robin, Schmidt, Carsten Oliver, Rüdebusch, Julia, Jung, Matthias, Reisert, Marco, Weiss, Jakob, Löffler, Maximilian, Bamberg, Fabian, Wiestler, Bene, Paetzold, Johannes C., Rueckert, Daniel, Kirschke, Jan Stefan
Objectives: To present a publicly available torso segmentation network for large epidemiology datasets on volumetric interpolated breath-hold examination (VIBE) images. Materials & Methods: We extracted preliminary segmentations from TotalSegmentator, spine, and body composition networks for VIBE images, then improved them iteratively and retrained a nnUNet network. Using subsets of NAKO (85 subjects) and UK Biobank (16 subjects), we evaluated with Dice-score on a holdout set (12 subjects) and existing organ segmentation approach (1000 subjects), generating 71 semantic segmentation types for VIBE images. We provide an additional network for the vertebra segments 22 individual vertebra types. Results: We achieved an average Dice score of 0.89 +- 0.07 overall 71 segmentation labels. We scored > 0.90 Dice-score on the abdominal organs except for the pancreas with a Dice of 0.70. Conclusion: Our work offers a detailed and refined publicly available full torso segmentation on VIBE images.
TopCoW: Benchmarking Topology-Aware Anatomical Segmentation of the Circle of Willis (CoW) for CTA and MRA
Yang, Kaiyuan, Musio, Fabio, Ma, Yihui, Juchler, Norman, Paetzold, Johannes C., Al-Maskari, Rami, Höher, Luciano, Li, Hongwei Bran, Hamamci, Ibrahim Ethem, Sekuboyina, Anjany, Shit, Suprosanna, Huang, Houjing, Waldmannstetter, Diana, Kofler, Florian, Navarro, Fernando, Menten, Martin, Ezhov, Ivan, Rueckert, Daniel, Vos, Iris, Ruigrok, Ynte, Velthuis, Birgitta, Kuijf, Hugo, Hämmerli, Julien, Wurster, Catherine, Bijlenga, Philippe, Westphal, Laura, Bisschop, Jeroen, Colombo, Elisa, Baazaoui, Hakim, Makmur, Andrew, Hallinan, James, Wiestler, Bene, Kirschke, Jan S., Wiest, Roland, Montagnon, Emmanuel, Letourneau-Guillon, Laurent, Galdran, Adrian, Galati, Francesco, Falcetta, Daniele, Zuluaga, Maria A., Lin, Chaolong, Zhao, Haoran, Zhang, Zehan, Ra, Sinyoung, Hwang, Jongyun, Park, Hyunjin, Chen, Junqiang, Wodzinski, Marek, Müller, Henning, Shi, Pengcheng, Liu, Wei, Ma, Ting, Yalçin, Cansu, Hamadache, Rachika E., Salvi, Joaquim, Llado, Xavier, Estrada, Uma Maria Lal-Trehan, Abramova, Valeriia, Giancardo, Luca, Oliver, Arnau, Liu, Jialu, Huang, Haibin, Cui, Yue, Lin, Zehang, Liu, Yusheng, Zhu, Shunzhi, Patel, Tatsat R., Tutino, Vincent M., Orouskhani, Maysam, Wang, Huayu, Mossa-Basha, Mahmud, Zhu, Chengcheng, Rokuss, Maximilian R., Kirchhoff, Yannick, Disch, Nico, Holzschuh, Julius, Isensee, Fabian, Maier-Hein, Klaus, Sato, Yuki, Hirsch, Sven, Wegener, Susanne, Menze, Bjoern
The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain. Its vascular architecture is believed to affect the risk, severity, and clinical outcome of serious neuro-vascular diseases. However, characterizing the highly variable CoW anatomy is still a manual and time-consuming expert task. The CoW is usually imaged by two angiographic imaging modalities, magnetic resonance angiography (MRA) and computed tomography angiography (CTA), but there exist limited public datasets with annotations on CoW anatomy, especially for CTA. Therefore we organized the TopCoW Challenge in 2023 with the release of an annotated CoW dataset. The TopCoW dataset was the first public dataset with voxel-level annotations for thirteen possible CoW vessel components, enabled by virtual-reality (VR) technology. It was also the first large dataset with paired MRA and CTA from the same patients. TopCoW challenge formalized the CoW characterization problem as a multiclass anatomical segmentation task with an emphasis on topological metrics. We invited submissions worldwide for the CoW segmentation task, which attracted over 140 registered participants from four continents. The top performing teams managed to segment many CoW components to Dice scores around 90%, but with lower scores for communicating arteries and rare variants. There were also topological mistakes for predictions with high Dice scores. Additional topological analysis revealed further areas for improvement in detecting certain CoW components and matching CoW variant topology accurately. TopCoW represented a first attempt at benchmarking the CoW anatomical segmentation task for MRA and CTA, both morphologically and topologically.