Metamaterials, renowned for their exceptional mechanical, electromagnetic, and thermal properties, hold transformative potential across diverse applications, yet their design remains constrained by labor - intensive trial - and - error methods and limited data interoperability. Here, we introduce CrossMatAgent -- a novel multi - agent framework that synergistically integrates large language models with state - of - the - art generative AI to revolutionize metamaterial design. By orchestrating a hierarchical team of agents -- e ach specializing in tasks such as pattern analysis, architectural synthesis, prompt engineering, and supervisory feedback -- our system leverages the multimodal reasoning of GPT - 4o alongside the generative precision of DALL - E 3 and a fine - tuned Stable Diffusion Extra Large ( XL) model. This integrated approach automates data augmentation, enhances design fidelity, and produces simulation - and 3D printing - ready metamaterial patterns. Comprehensive evaluations, including Contrastive Language - Image Pre - training ( C LIP) - based alignment, SHAP ( SHapley Additive exPlanations) interpretability analyses, and mechanical simulations under varied load conditions, demonstrate the framework's ability to generate diverse, reproducible, and application - ready designs . CrossMatAgent thus establishes a scalable, AI - driven paradigm that bridges the gap between conceptual innovation and practical realization, paving the way for accelerated metamaterial development.

A core challenge for signal data recovery is to model the distribution of signal matrix (SM) data based on measured low-quality data in biomedical engineering of magnetic particle imaging (MPI). For acquiring the high-resolution (high-quality) SM, the number of meticulous measurements at numerous positions in the field-of-view proves time-consuming (measurement of a 37x37x37 SM takes about 32 hours). To improve reconstructed signal quality and shorten SM measurement time, existing methods explore to generating high-resolution SM based on time-saving measured low-resolution SM (a 9x9x9 SM just takes about 0.5 hours). However, previous methods show poor performance for high-frequency signal recovery in SM. To achieve a high-resolution SM recovery and shorten its acquisition time, we propose a frequency-domain structure consistency loss function and data component embedding strategy to model global and local structural information of SM. We adopt a transformer-based network to evaluate this function and the strategy. We evaluate our methods and state-of-the-art (SOTA) methods on the two simulation datasets and four public measured SMs in Open MPI Data. The results show that our method outperforms the SOTA methods in high-frequency structural signal recovery. Additionally, our method can recover a high-resolution SM with clear high-frequency structure based on a down-sampling factor of 16 less than 15 seconds, which accelerates the acquisition time over 60 times faster than the measurement-based HR SM with the minimum error (nRMSE=0.041). Moreover, our method is applied in our three in-house MPI systems, and boost their performance for signal reconstruction.

The rapid advances in Large Language Models (LLMs) have the potential to transform manufacturing industry, offering new opportunities to optimize processes, improve efficiency, and drive innovation. This paper provides a comprehensive exploration of the integration of LLMs into the manufacturing domain, focusing on their potential to automate and enhance various aspects of manufacturing, from product design and development to quality control, supply chain optimization, and talent management. Through extensive evaluations across multiple manufacturing tasks, we demonstrate the remarkable capabilities of state-of-the-art LLMs, such as GPT-4V, in understanding and executing complex instructions, extracting valuable insights from vast amounts of data, and facilitating knowledge sharing. We also delve into the transformative potential of LLMs in reshaping manufacturing education, automating coding processes, enhancing robot control systems, and enabling the creation of immersive, data-rich virtual environments through the industrial metaverse. By highlighting the practical applications and emerging use cases of LLMs in manufacturing, this paper aims to provide a valuable resource for professionals, researchers, and decision-makers seeking to harness the power of these technologies to address real-world challenges, drive operational excellence, and unlock sustainable growth in an increasingly competitive landscape.

Text classification is a crucial task encountered frequently in practical scenarios, yet it is still under-explored in the era of large language models (LLMs). This study shows that LLMs are vulnerable to changes in the number and arrangement of options in text classification. Our extensive empirical analyses reveal that the key bottleneck arises from ambiguous decision boundaries and inherent biases towards specific tokens and positions. To mitigate these issues, we make the first attempt and propose a novel two-stage classification framework for LLMs. Our approach is grounded in the empirical observation that pairwise comparisons can effectively alleviate boundary ambiguity and inherent bias. Specifically, we begin with a self-reduction technique to efficiently narrow down numerous options, which contributes to reduced decision space and a faster comparison process. Subsequently, pairwise contrastive comparisons are employed in a chain-of-thought manner to draw out nuances and distinguish confusable options, thus refining the ambiguous decision boundary. Extensive experiments on four datasets (Banking77, HWU64, LIU54, and Clinic150) verify the effectiveness of our framework. Furthermore, benefitting from our framework, various LLMs can achieve consistent improvements. Our code and data are available in \url{https://github.com/Chuge0335/PC-CoT}.

This study is a pioneering endeavor to investigate the capabilities of Large Language Models (LLMs) in addressing conceptual questions within the domain of mechanical engineering with a focus on mechanics. Our examination involves a manually crafted exam encompassing 126 multiple-choice questions, spanning various aspects of mechanics courses, including Fluid Mechanics, Mechanical Vibration, Engineering Statics and Dynamics, Mechanics of Materials, Theory of Elasticity, and Continuum Mechanics. Three LLMs, including ChatGPT (GPT-3.5), ChatGPT (GPT-4), and Claude (Claude-2.1), were subjected to evaluation against engineering faculties and students with or without mechanical engineering background. The findings reveal GPT-4's superior performance over the other two LLMs and human cohorts in answering questions across various mechanics topics, except for Continuum Mechanics. This signals the potential future improvements for GPT models in handling symbolic calculations and tensor analyses. The performances of LLMs were all significantly improved with explanations prompted prior to direct responses, underscoring the crucial role of prompt engineering. Interestingly, GPT-3.5 demonstrates improved performance with prompts covering a broader domain, while GPT-4 excels with prompts focusing on specific subjects. Finally, GPT-4 exhibits notable advancements in mitigating input bias, as evidenced by guessing preferences for humans. This study unveils the substantial potential of LLMs as highly knowledgeable assistants in both mechanical pedagogy and scientific research.

Directly predicting human epidermal growth factor receptor 2 (HER2) status from widely available hematoxylin and eosin (HE)-stained whole slide images (WSIs) can reduce technical costs and expedite treatment selection. Accurately predicting HER2 requires large collections of multi-site WSIs. Federated learning enables collaborative training of these WSIs without gigabyte-size WSIs transportation and data privacy concerns. However, federated learning encounters challenges in addressing label imbalance in multi-site WSIs from the real world. Moreover, existing WSI classification methods cannot simultaneously exploit local context information and long-range dependencies in the site-end feature representation of federated learning. To address these issues, we present a point transformer with federated learning for multi-site HER2 status prediction from HE-stained WSIs. Our approach incorporates two novel designs. We propose a dynamic label distribution strategy and an auxiliary classifier, which helps to establish a well-initialized model and mitigate label distribution variations across sites. Additionally, we propose a farthest cosine sampling based on cosine distance. It can sample the most distinctive features and capture the long-range dependencies. Extensive experiments and analysis show that our method achieves state-of-the-art performance at four sites with a total of 2687 WSIs. Furthermore, we demonstrate that our model can generalize to two unseen sites with 229 WSIs.

A core challenge in survival analysis is to model the distribution of censored time-to-event data, where the event of interest may be a death, failure, or occurrence of a specific event. Previous studies have showed that ranking and maximum likelihood estimation (MLE)loss functions are widely-used for survival analysis. However, ranking loss only focus on the ranking of survival time and does not consider potential effect of samples for exact survival time values. Furthermore, the MLE is unbounded and easily subject to outliers (e.g., censored data), which may cause poor performance of modeling. To handle the complexities of learning process and exploit valuable survival time values, we propose a time-adaptive coordinate loss function, TripleSurv, to achieve adaptive adjustments by introducing the differences in the survival time between sample pairs into the ranking, which can encourage the model to quantitatively rank relative risk of pairs, ultimately enhancing the accuracy of predictions. Most importantly, the TripleSurv is proficient in quantifying the relative risk between samples by ranking ordering of pairs, and consider the time interval as a trade-off to calibrate the robustness of model over sample distribution. Our TripleSurv is evaluated on three real-world survival datasets and a public synthetic dataset. The results show that our method outperforms the state-of-the-art methods and exhibits good model performance and robustness on modeling various sophisticated data distributions with different censor rates. Our code will be available upon acceptance.

The precise cerebrovascular segmentation in time-of-flight magnetic resonance angiography (TOF-MRA) data is crucial for clinically computer-aided diagnosis. However, the sparse distribution of cerebrovascular structures in TOF-MRA results in an exceedingly high cost for manual data labeling. The use of unlabeled TOF-MRA data holds the potential to enhance model performance significantly. In this study, we construct the largest preprocessed unlabeled TOF-MRA datasets (1510 subjects) to date. We also provide three additional labeled datasets totaling 113 subjects. Furthermore, we propose a simple yet effective pertraining strategy based on Frangi filtering, known for enhancing vessel-like structures, to fully leverage the unlabeled data for 3D cerebrovascular segmentation. Specifically, we develop a Frangi filtering-based preprocessing workflow to handle the large-scale unlabeled dataset, and a multi-task pretraining strategy is proposed to effectively utilize the preprocessed data. By employing this approach, we maximize the knowledge gained from the unlabeled data. The pretrained model is evaluated on four cerebrovascular segmentation datasets. The results have demonstrated the superior performance of our model, with an improvement of approximately 3\% compared to state-of-the-art semi- and self-supervised methods. Furthermore, the ablation studies also demonstrate the generalizability and effectiveness of the pretraining method regarding the backbone structures. The code and data have been open source at: \url{https://github.com/shigen-StoneRoot/FFPN}.

Segmentation of COVID-19 lesions can assist physicians in better diagnosis and treatment of COVID-19. However, there are few relevant studies due to the lack of detailed information and high-quality annotation in the COVID-19 dataset. To solve the above problem, we propose C2FVL, a Coarse-to-Fine segmentation framework via Vision-Language alignment to merge text information containing the number of lesions and specific locations of image information. The introduction of text information allows the network to achieve better prediction results on challenging datasets. We conduct extensive experiments on two COVID-19 datasets including chest X-ray and CT, and the results demonstrate that our proposed method outperforms other state-of-the-art segmentation methods.

New intelligence applications are driving increasing interest in deploying deep neural networks (DNN) in a distributed way. To set up distributed deep learning involves alterations of a great number of the parameter configurations of network/edge devices and DNN models, which are crucial to achieve best performances. Simulations measure scalability of intelligence applications in the early stage, as well as to determine the effects of different configurations, thus highly desired. However, work on simulating the distributed intelligence environment is still in its infancy. The existing simulation frameworks, such as NS-3, etc., cannot extended in a straightforward way to support simulations of distributed learning. In this paper, we propose a novel discrete event simulator, sim4DistrDL, which includes a deep learning module and a network simulation module to facilitate simulation of DNN-based distributed applications. Specifically, we give the design and implementation of the proposed learning simulator and present an illustrative use case.