Quaglini, Silvana
Defining Effective Engagement For Enhancing Cancer Patients' Well-being with Mobile Digital Behavior Change Interventions
Lisowska, Aneta, Wilk, Szymon, Locati, Laura, Rizzo, Mimma, Sacchi, Lucia, Quaglini, Silvana, Terzaghi, Matteo, Tibollo, Valentina, Peleg, Mor
Digital Behavior Change Interventions (DBCIs) are supporting development of new health behaviors. Evaluating their effectiveness is crucial for their improvement and understanding of success factors. However, comprehensive guidance for developers, particularly in small-scale studies with ethical constraints, is limited. Building on the CAPABLE project, this study aims to define effective engagement with DBCIs for supporting cancer patients in enhancing their quality of life. We identify metrics for measuring engagement, explore the interest of both patients and clinicians in DBCIs, and propose hypotheses for assessing the impact of DBCIs in such contexts. Our findings suggest that clinician prescriptions significantly increase sustained engagement with mobile DBCIs. In addition, while one weekly engagement with a DBCI is sufficient to maintain well-being, transitioning from extrinsic to intrinsic motivation may require a higher level of engagement.
Use of Patient Generated Data from Social Media and Collaborative Filtering for Preferences Elicitation in Shared Decision Making
Parimbelli, Enea (University of Pavia) | Quaglini, Silvana (University of Pavia) | Napolitano, Carlo (IRCCS Fondazione Salvatore Maugeri) | Priori, Silvia (IRCCS Fondazione Salvatore Maugeri) | Bellazzi, Riccardo (University of Pavia, IRCCS Fondazione Salvatore Maugeri) | Holmes, John (University of Pennsylvania)
With the increasing demand for personalization in clinical decision support system, one of the most challenging tasks is effective patient preferences elicitation. In the context of the MobiGuide project, within a medical application related to atrial fibrillation, a decision support system has been developed for both doctors and patients. In particular, we support shared decision-making, by integrating decision tree models with a dedicated tool for utility coefficients elicitation. In this paper we focus on the decision problem regarding the choice of anticoagulant therapy for low risk non-valvular atrial fibrillation patients. In addition to the traditional methods, such as time trade-off and standard gamble, an alternative way for preferences elicitation is proposed, exploiting patients’ self-reported data in health-related social media as the main source of information.
Temporal Reasoning with Probabilities
Berzuini, Carlo, Bellazzi, Riccardo, Quaglini, Silvana
In this paper we explore representations of temporal knowledge based upon the formalism of Causal Probabilistic Networks (CPNs). Two different ?continuous-time? representations are proposed. In the first, the CPN includes variables representing ?event-occurrence times?, possibly on different time scales, and variables representing the ?state? of the system at these times. In the second, the CPN describes the influences between random variables with values in () representing dates, i.e. time-points associated with the occurrence of relevant events. However, structuring a system of inter-related dates as a network where all links commit to a single specific notion of cause and effect is in general far from trivial and leads to severe difficulties. We claim that we should recognize explicitly different kinds of relation between dates, such as ?cause?, ?inhibition?, ?competition?, etc., and propose a method whereby these relations are coherently embedded in a CPN using additional auxiliary nodes corresponding to "instrumental" variables. Also discussed, though not covered in detail, is the topic concerning how the quantitative specifications to be inserted in a temporal CPN can be learned from specific data.