The EM-algorithm is a general procedure to get maximum likelihood estimates if part of the observations on the variables of a network are missing. In this paper a stochastic version of the algorithm is adapted to probabilistic neural networks describing the associative dependency of variables. These networks have a probability distribution, which is a special case of the distribution generated by probabilistic inference networks. Hence both types of networks can be combined allowing to integrate probabilistic rules as well as unspecified associations in a sound way. The resulting network may have a number of interesting features including cycles of probabilistic rules, hidden 'unobservable' variables, and uncertain and contradictory evidence.

If data collection is costly, there is much to be gained by actively selecting particularlyinformative data points in a sequential way. In a Bayesian decision-theoretic framework we develop a query selection criterionwhich explicitly takes into account the intended use of the model predictions. By Markov Chain Monte Carlo methods the necessary quantities can be approximated to a desired precision. Asthe number of data points grows, the model complexity is modified by a Bayesian model selection strategy. The properties oftwo versions of the criterion ate demonstrated in numerical experiments.

If data collection is costly, there is much to be gained by actively selecting particularly informative data points in a sequential way. In a Bayesian decision-theoretic framework we develop a query selection criterion which explicitly takes into account the intended use of the model predictions. By Markov Chain Monte Carlo methods the necessary quantities can be approximated to a desired precision. As the number of data points grows, the model complexity is modified by a Bayesian model selection strategy. The properties of two versions of the criterion ate demonstrated in numerical experiments.

The bootstrap method offers an computation intensive alternative to estimate the predictive distribution for a neural network even if the analytic derivation is intractable. Theavailable asymptotic results show that it is valid for a large number of linear, nonlinear and even nonparametric regression problems. It has the potential tomodel the distribution of estimators to a higher precision than the usual normal asymptotics. It even may be valid if the normal asymptotics fail. However, the theoretical properties of bootstrap procedures for neural networks - especially nonlinear models - have to be investigated more comprehensively.

The bootstrap method offers an computation intensive alternative to estimate the predictive distribution for a neural network even if the analytic derivation is intractable. The available asymptotic results show that it is valid for a large number of linear, nonlinear and even nonparametric regression problems. It has the potential to model the distribution of estimators to a higher precision than the usual normal asymptotics. It even may be valid if the normal asymptotics fail. However, the theoretical properties of bootstrap procedures for neural networks - especially nonlinear models - have to be investigated more comprehensively.