A "meta-study" or "meta-analysis" analyzes multiple medical studies related to the same disease, treatment protocol, and outcome measurement to identify if there is an overall effect or not (e.g., treatment induces remission or causes adverse effects). It's advantage lies in the pooling and analysis of results across independent studies, which increases the population size, mitigates some experimental bias or inconsistent results from a single study, etc. Meta-studies are important for understanding the effectiveness (or not) of treatment, influencing clinical guidelines and for spurring new research directions. However, meta-studies are extremely time consuming to construct by hand and keep updated with the latest results. This limits both their breadth of coverage (since researchers will only invest the time for diseases they are interested in) and their practically. Yet, high-quality medical research is increasing at a staggering rate, and there is an opportunity to apply automation to this increasing body of knowledge, thereby expanding the benefits of meta-studies to (theoretically) all diseases and treatment, as they are published. That is, we envision, long term an automatic process for creating meta-studies across all diseases and treatments, and keeping those meta-studies up-to-date automatically. In this paper we demonstrate that there is potential to perform this task, point out future research directions to make this so, and, hopefully, spur significant interest in this compelling and important research direction at the intersection of medical research and machine learning.

The need for health providers to share information is a pressing need in our ever more connected world. A patient's health information should seamlessly flow from labs to hospitals to primary care offices. To address this need, in this paper we present the Health E-Match, which focuses on the matching health terms in support of semantic interoperability. Health E-Match determines the semantic similarity between data items, realizing, for instance, that "BHGC (UR)" and "BETA-HCG (QUAL)" both refer to the same pregnancy test, known as "Beta human chorionic gonadotropin, urine qualitative." Our approach is grounded in probabilistic machine learning, and leverages several sophisticated methods for comparing the similarity between medical data items beyond simple edit distance. We present two large scale, real-world experiments to verify that our approach is both accurate and has the ability to eventually be "universal" in that models trained on one set of data translate to strong performance on data from a completely different provider.

Twitter and other microblogs have rapidly become a significant means by which people communicate with the world and each other in near realtime. There has been a large number of studies surrounding these social media, focusing on areas such as information spread, various centrality measures, topic detection and more. However, one area which has not received much attention is trying to better understand what information is being spread and why it is being spread. This work looks to get a better understanding of what makes people spread information in tweets or microblogs through the use of retweeting. Several retweet behavior models are presented and evaluated on a Twitter data set consisting of over 768,000 tweets gathered from monitoring over 30,000 users for a period of one month. We evaluate the proposed models against each user and show how people use different retweet behavior models. For example, we find that although users in the majority of cases do not retweet information on topics that they themselves Tweet about as or from people who are "like them" (hence anti-homophily), we do find that models which do take homophily, or similarity, into account fits the observed retweet behaviors much better than other more general models which do not take this into account. We further find that, not surprisingly, people's retweeting behavior is better explained through multiple different models rather than one model.

Wikis allow for collaborators to collect information about entities. In turn, such entity information can be used for AI tasks, such as information extraction. However, these collaborators are almost exclusively human users. Allowing arbitrary software agents to act as collaborators can greatly enrich a wiki since agents can contribute structured data to complement the human-contributed, unstructured-data. For instance, agents can import huge volumes of structured data about entities, enriching the pages, and agents can update wiki pages to reflect real-time information changes (e.g., win-loss records in sports). This paper describes an approach that allows for both arbitrary software agents and human users to collaborate. In particular, we address three key problems: agents updating the correct wiki pages, policies for agent updates, and sharing the schema across collaborators. Using our approach, we describe creating entity-focused wikis which include the ability to create dynamic categories of entities based on their wiki pages. These categories dynamically update their membership based upon real-world changes.

The goal of the Electric Elves project was to develop software agent technology to support human organizations. We developed a variety of applications of the Elves, including scheduling visitors, managing a research group (the Office Elves), and monitoring travel (the Travel Elves). The Travel Elves were eventually deployed at DARPA, where things did not go exactly as planned. In this article, we describe some of the things that went wrong and then present some of the lessons learned and new research that arose from our experience in building the Travel Elves.

In fact, DARPA, which funded the project, ways. Elves) (Scerri, Pynadath, and Tambe 2002; Finally, we will present some lessons Pynadath and Tambe 2003) and required learned and recent research that was motivated detailed information about the calendars by our experiences in deploying the of people using the system. Thus, we decided to deploy a new application of the Electric The Travel Elves introduced two major Elves, called the Travel Elves. This application advantages over traditional approaches to appeared to be ideal for wider deployment travel planning. First, the Travel Elves provided since it could be hosted entirely outside an interactive approach to making an organization and communication travel plans in which all of the data could be performed over wireless devices, required to make informed choices is such as cellular telephones. For example, when The mission of the Travel Elves (Ambite deciding whether to park at the airport or et al. 2002, Knoblock 2004) was to facilitate take a taxi, the system compares the cost planning a trip and to ensure that the of parking and the cost of a taxi given other resulting travel plan would execute selections, such as the airport, the specific smoothly. Initial deployment of the Travel parking lot, and the starting location Elves at DARPA went smoothly.