This paper presents a new algorithmic fairness framework called $\boldsymbol{\alpha}$-$\boldsymbol{\beta}$ Fair Machine Learning ($\boldsymbol{\alpha}$-$\boldsymbol{\beta}$ FML), designed to optimize fairness levels across sociodemographic attributes. Our framework employs a new family of surrogate loss functions, paired with loss reweighting techniques, allowing precise control over fairness-accuracy trade-offs through tunable hyperparameters $\boldsymbol{\alpha}$ and $\boldsymbol{\beta}$. To efficiently solve the learning objective, we propose Parallel Stochastic Gradient Descent with Surrogate Loss (P-SGD-S) and establish convergence guarantees for both convex and nonconvex loss functions. Experimental results demonstrate that our framework improves overall accuracy while reducing fairness violations, offering a smooth trade-off between standard empirical risk minimization and strict minimax fairness. Results across multiple datasets confirm its adaptability, ensuring fairness improvements without excessive performance degradation.

Despite the growing scale of medical Vision-Language datasets, the impact of dataset quality on model performance remains under-explored. We introduce Open-PMC, a high-quality medical dataset from PubMed Central, containing 2.2 million image-text pairs, enriched with image modality annotations, subfigures, and summarized in-text references. Notably, the in-text references provide richer medical context, extending beyond the abstract information typically found in captions. Through extensive experiments, we benchmark Open-PMC against larger datasets across retrieval and zero-shot classification tasks. Our results show that dataset quality-not just size-drives significant performance gains. We complement our benchmark with an in-depth analysis of feature representation. Our findings highlight the crucial role of data curation quality in advancing multimodal medical AI. We release Open-PMC, along with the trained models and our codebase.

This position paper argues for a fundamental shift in how Large Language Models (LLMs) are integrated into the mental health care domain. We advocate for their role as co-creators rather than mere assistive tools. While LLMs have the potential to enhance accessibility, personalization, and crisis intervention, their adoption remains limited due to concerns about bias, evaluation, over-reliance, dehumanization, and regulatory uncertainties. To address these challenges, we propose two structured pathways: SAFE-i (Supportive, Adaptive, Fair, and Ethical Implementation) Guidelines for ethical and responsible deployment, and HAAS-e (Human-AI Alignment and Safety Evaluation) Framework for multidimensional, human-centered assessment. SAFE-i provides a blueprint for data governance, adaptive model engineering, and real-world integration, ensuring LLMs align with clinical and ethical standards. HAAS-e introduces evaluation metrics that go beyond technical accuracy to measure trustworthiness, empathy, cultural sensitivity, and actionability. We call for the adoption of these structured approaches to establish a responsible and scalable model for LLM-driven mental health support, ensuring that AI complements-rather than replaces-human expertise.

The rapid rise of AI-generated content has made detecting disinformation increasingly challenging. In particular, multimodal disinformation, i.e., online posts-articles that contain images and texts with fabricated information are specially designed to deceive. While existing AI safety benchmarks primarily address bias and toxicity, multimodal disinformation detection remains largely underexplored. To address this challenge, we present the Vision-Language Disinformation Detection Benchmark VLDBench, the first comprehensive benchmark for detecting disinformation across both unimodal (text-only) and multimodal (text and image) content, comprising 31,000} news article-image pairs, spanning 13 distinct categories, for robust evaluation. VLDBench features a rigorous semi-automated data curation pipeline, with 22 domain experts dedicating 300 plus hours} to annotation, achieving a strong inter-annotator agreement (Cohen kappa = 0.78). We extensively evaluate state-of-the-art Large Language Models (LLMs) and Vision-Language Models (VLMs), demonstrating that integrating textual and visual cues in multimodal news posts improves disinformation detection accuracy by 5 - 35 % compared to unimodal models. Developed in alignment with AI governance frameworks such as the EU AI Act, NIST guidelines, and the MIT AI Risk Repository 2024, VLDBench is expected to become a benchmark for detecting disinformation in online multi-modal contents. Our code and data will be publicly available.

Understanding the prevalence, disparities, and symptom variations of Post COVID-19 Condition (PCC) for vulnerable populations is crucial to improving care and addressing intersecting inequities. This study aims to develop a comprehensive framework for integrating social determinants of health (SDOH) into PCC research by leveraging NLP techniques to analyze disparities and variations in SDOH representation within PCC case reports. Following construction of a PCC Case Report Corpus, comprising over 7,000 case reports from the LitCOVID repository, a subset of 709 reports were annotated with 26 core SDOH-related entity types using pre-trained named entity recognition (NER) models, human review, and data augmentation to improve quality, diversity and representation of entity types. An NLP pipeline integrating NER, natural language inference (NLI), trigram and frequency analyses was developed to extract and analyze these entities. Both encoder-only transformer models and RNN-based models were assessed for the NER objective. Fine-tuned encoder-only BERT models outperformed traditional RNN-based models in generalizability to distinct sentence structures and greater class sparsity. Exploratory analysis revealed variability in entity richness, with prevalent entities like condition, age, and access to care, and underrepresentation of sensitive categories like race and housing status. Trigram analysis highlighted frequent co-occurrences among entities, including age, gender, and condition. The NLI objective (entailment and contradiction analysis) showed attributes like "Experienced violence or abuse" and "Has medical insurance" had high entailment rates (82.4%-80.3%), while attributes such as "Is female-identifying," "Is married," and "Has a terminal condition" exhibited high contradiction rates (70.8%-98.5%).

In this study, we introduce the application of causal disparity analysis to unveil intricate relationships and causal pathways between sensitive attributes and the targeted outcomes within real-world observational data. Our methodology involves employing causal decomposition analysis to quantify and examine the causal interplay between sensitive attributes and outcomes. We also emphasize the significance of integrating heterogeneity assessment in causal disparity analysis to gain deeper insights into the impact of sensitive attributes within specific sub-groups on outcomes. Our two-step investigation focuses on datasets where race serves as the sensitive attribute. The results on two datasets indicate the benefit of leveraging causal analysis and heterogeneity assessment not only for quantifying biases in the data but also for disentangling their influences on outcomes. We demonstrate that the sub-groups identified by our approach to be affected the most by disparities are the ones with the largest ML classification errors. We also show that grouping the data only based on a sensitive attribute is not enough, and through these analyses, we can find sub-groups that are directly affected by disparities. We hope that our findings will encourage the adoption of such methodologies in future ethical AI practices and bias audits, fostering a more equitable and fair technological landscape.

The world's healthcare systems and mental health agencies face both a growing demand for youth mental health services, alongside a simultaneous challenge of limited resources. Here, we focus on frontline crisis support, where Crisis Responders (CRs) engage in conversations for youth mental health support and assign an issue tag to each conversation. In this study, we develop FAIIR (Frontline Assistant: Issue Identification and Recommendation), an advanced tool leveraging an ensemble of domain-adapted and fine-tuned transformer models trained on a large conversational dataset comprising 780,000 conversations. The primary aim is to reduce the cognitive burden on CRs, enhance the accuracy of issue identification, and streamline post-conversation administrative tasks. We evaluate FAIIR on both retrospective and prospective conversations, emphasizing human-in-the-loop design with active CR engagement for model refinement, consensus-building, and overall assessment. Our results indicate that FAIIR achieves an average AUCROC of 94%, a sample average F1-score of 64%, and a sample average recall score of 81% on the retrospective test set. We also demonstrate the robustness and generalizability of the FAIIR tool during the silent testing phase, with less than a 2% drop in all performance metrics. Notably, CRs' responses exhibited an overall agreement of 90.9% with FAIIR's predictions. Furthermore, expert agreement with FAIIR surpassed their agreement with the original labels. To conclude, our findings indicate that assisting with the identification of issues of relevance helps reduce the burden on CRs, ensuring that appropriate resources can be provided and that active rescues and mandatory reporting can take place in critical situations requiring immediate de-escalation.

We perform a comprehensive benchmarking of contrastive frameworks for learning multimodal representations in the medical domain. Through this study, we aim to answer the following research questions: (i) How transferable are general-domain representations to the medical domain? (ii) Is multimodal contrastive training sufficient, or does it benefit from unimodal training as well? (iii) What is the impact of feature granularity on the effectiveness of multimodal medical representation learning? To answer these questions, we investigate eight contrastive learning approaches under identical training setups, and train them on 2.8 million image-text pairs from four datasets, and evaluate them on 25 downstream tasks, including classification (zero-shot and linear probing), image-to-text and text-to-image retrieval, and visual question-answering. Our findings suggest a positive answer to the first question, a negative answer to the second question, and the benefit of learning fine-grained features. Finally, we make our code publicly available.

Machine Learning Health Operations (MLHOps) is the combination of processes for reliable, efficient, usable, and ethical deployment and maintenance of machine learning models in healthcare settings. This paper provides both a survey of work in this area and guidelines for developers and clinicians to deploy and maintain their own models in clinical practice. We cover the foundational concepts of general machine learning operations, describe the initial setup of MLHOps pipelines (including data sources, preparation, engineering, and tools). We then describe long-term monitoring and updating (including data distribution shifts and model updating) and ethical considerations (including bias, fairness, interpretability, and privacy). This work therefore provides guidance across the full pipeline of MLHOps from conception to initial and ongoing deployment.

Building Agent Assistants that can help improve customer service support requires inputs from industry users and their customers, as well as knowledge about state-of-the-art Natural Language Processing (NLP) technology. We combine expertise from academia and industry to bridge the gap and build task/domain-specific Neural Agent Assistants (NAA) with three high-level components for: (1) Intent Identification, (2) Context Retrieval, and (3) Response Generation. In this paper, we outline the pipeline of the NAA's core system and also present three case studies in which three industry partners successfully adapt the framework to find solutions to their unique challenges. Our findings suggest that a collaborative process is instrumental in spurring the development of emerging NLP models for Conversational AI tasks in industry. The full reference implementation code and results are available at \url{https://github.com/VectorInstitute/NAA}