Anatomical origin and computational role of diversity in the response properties of cortical neurons

A fundamental feature of cortical architecture is its columnar organization, manifested in the tendency of neurons with similar properties to be organized in columns that run perpendicular to the cortical surface. This organization of the cortex was initially discovered by physiological experiments (Mouncastle, 1957; Hubel and Wiesel, 1962), and subsequently confirmed with the demonstration of histologically defined that axonal projections throughout thecolumns. Tracing experiments have shown tend to be organized in vertically aligned clusters or patches.