Redefining Cancer Treatment- The Memorial Sloan Way

Whenever a patient has symptoms of cancer, the cancer tumour is taken out and sequenced. Genetic information in the tumor cell is stored in the form of DNA. It is then transcribed to form RNA which is then translated to form proteins/amino acids. In case of a mutation, or a mistake in DNA sequence, the resultant amino acid is affected giving rise to a variation for the particular gene. Thousands of genetic mutations may be present in the sequence. We need to distinguish the malignant mutations (drivers leading to tumour growth) from the benign (passenger) ones.