Identifying Cells to Better Understand Healthy and Diseased Behavior

In researching the causes and potential treatments for degenerative conditions such as Alzheimer's or Parkinson's disease, neuroscientists frequently struggle to accurately identify cells needed to understand brain activity that gives rise to behavior changes such as declining memory or impaired balance and tremors. A multidisciplinary team of Georgia Institute of Technology neuroscience researchers, borrowing from existing tools such as graphical models, have uncovered a better way to identify cells and understand the mechanisms of the diseases, potentially leading to better understanding, diagnosis, and treatment. Their research findings were reported Feb. 24 in the journal eLife. The research was supported by the National Institutes of Health and the National Science Foundation. By using new technologies to understand natural and dysfunctional states of biological systems, neuroscientists hope to ultimately bring cures to diseases.