NAD Supplement 101: Possible Benefits and Precautions Explained (2026)

What NAD+? Here's how it works in your body, why it matters, and if supplementation is worth the hype. It's more than likely that the NAD+ supplement craze has already crossed your path. The Biebers have infused it. Joe Rogan has podcasted about it. Gwyneth Paltrow swears by it and, of course, sells her own Youth-Boost NAD+ Peptide Rich Cream . NAD+ (short for nicotinamide adenine dinucleotide) is a coenzyme that your body makes naturally--it contributes to energy production and immune function, among other things. It reflects a broader shift in how people think about healthy aging and extending their healthspan overall .