Artificial intelligence - good or bad for public health?
Over the course of his career, Quackenbush has been a vocal advocate for transparency and data sharing, so much so that President Barack Obama named him a White House Open Science Champion of Change in 2013 for his efforts to ensure that vast amounts of genomic data are accessible to researchers around the world. Reproducibility is the essence of the scientific method, Quackenbush says, and it is of the utmost importance when new technologies are being floated for use in human clinical trials. As a cautionary tale, Quackenbush mentions Anil Potti, a former Duke University professor who in the early 2000s claimed to have discovered genetic signatures that could determine how individuals with certain cancers would respond to chemotherapy. The technique sailed into human clinical trials even though other researchers reported that they were unable to reproduce Potti's findings. Eventually it was revealed that Potti had falsified data and study results, and the whole house of biomedical cards came crashing down.
Apr-2-2022, 04:35:14 GMT
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