MRI Manufacturer Shift and Adaptation: Increasing the Generalizability of Deep Learning Segmentation for MR Images Acquired with Different Scanners

To quantitatively evaluate the generalizability of a deep learning segmentation tool to MRI data from scanners of different MRI manufacturers and to improve the cross-manufacturer performance by using a manufacturer-adaptation strategy. This retrospective study included 150 cine MRI datasets from three MRI manufacturers, acquired between 2017 and 2018 (n 50 for manufacturer 1, manufacturer 2, and manufacturer 3). Three convolutional neural networks (CNNs) were trained to segment the left ventricle (LV), using datasets exclusively from images from a single manufacturer. A generative adversarial network (GAN) was trained to adapt the input image before segmentation. The LV segmentation performance, end-diastolic volume (EDV), end-systolic volume (ESV), LV mass, and LV ejection fraction (LVEF) were evaluated before and after manufacturer adaptation.