Machine learning and systems genomics approaches for multi-omics data

Multiple predictive models are generated by using various multi-omics data types; then a final predictive model is generated by using the multiple models. Predictive models can be consolidated from various multi-omics data types, and each data type can be gathered from a various set of patients with same phenotype. Multiple data matrices of different multi-omics data types are incorporated into a large input matrix; then a predictive model is generated by using the large input matrix. It is fairly easy to leverage various machine learning methods for analyzing continuous or categorical data once a large input matrix is formed. It may be challenging to combine a large input matrix. Datasets for various multi-omics data types are first converted into intermediate forms, which are united into a large input matrix; then a predictive model is generated by using the large input matrix. Unique variables such as patient identifiers can be used to link multi-omics data types and integrate a variety of continuous or categorical data values. It may be challenging to transform into intermediate forms.