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The Twelfth Innovative Applications of Artificial Intelligence Conference (IAAI-2000) will run concurrently with the main technical conference this year on Tuesday, August 1, and Wednesday, August 2. IAAI-2000 will honor six case studies of fully deployed applications with measurable benefits whose value depends on the use of AI technology. This year's papers address applications in a wide variety of domains, including large-scale scheduling, biotechnology, medical data mining, civil engineering, financial modeling, email management, manufacturing, and interactive agents. AI techniques discussed include knowledge-based systems, vision, constraint programming, machine learning, software synthesis, planning and execution, natural language processing, diagnostic reasoning, reasoning with uncertainty, neural networks, and cognitive simulation. The innovative applications conference is intended not only for those involved in applications but also for researchers interested in gaining a better understanding of the applications side of the AI equation. The AAAI-2000 exhibition will offer a wide variety of programs, including the Ninth Annual Mobile Robot Competition and Exhibition, the Intelligent Systems Demonstrations, the final round of the National Botball Tournament, and the finals of the AAAI-2000 Robot Building Laboratory contest.